Effects of vitamin E, age and sex on performance of Japanese quail. 1. Haematological indices and liver function

Abstract

1. A trial was conducted to examine the effects of dietary vitamin E content, age and sex on haematological indices and liver enzymes of Japanese quails. A total of 800 1-d-old quail chicks were assigned at random into 4 equal groups and fed on starter and layer diets containing 0, 1, 5 or 10 times the NRC recommended supplements of vitamin E. No selenium was added to the basal deficient diets; the other diets were supplied with 0.2 mg selenium/kg diet. 2. The investigation covered the age span of 3 to 12 weeks in female and male birds. Blood samples were collected at 3-week intervals and tested for haematological indices (erythrocyte count; leucocyte count; susceptibility of erythrocytes to haemolysis; haemoglobin concentration (Hb); packed cell volume (PCV); and mean corpuscular volume (MCV)) and liver enzymes (aspartate transaminase, AST, and glutathione peroxidase, GSH-Px). 3. The significant differences between the 4 dietary treatments indicated that as the levels of selenium and/or vitamin E increased, the percentage of erythrocytes haemolysed and AST activity decreased, whereas Hb and GSH-Px concentrations increased. 4. Differences between age groups showed that older quails had higher erythrocyte susceptibility to haemolysis, higher AST levels and but lower erythrocyte count and PCV. 5. Females had lower erythrocyte haemolysis and higher Hb concentrations than males. 6. The interaction between dietary groups and age groups revealed that the differences between age groups were reduced as the level of selenium and/or vitamin E increased, leading to similar group means over the age period of study. 7. In conclusion, NRC recommended supplements of vitamin E (12 and 25 mg/kg diet) were not adequate. Doses equal to, at least, 5 times that recommended were advised to improve GSH-Px (index of antioxidant status) and Hb concentrations.

Novel Therapeutic Use of Insulin and Vitamin E in (Nafld) Using Fatty Liver Induced Rats.

“…The therapeutic use of antioxidant vitamins has gained considerable interest during the last decade. Previous animal and human studies showed that vitamin E might play a role in preventing the oxidation of polyunsaturated fatty acids in erythrocytes membrane (Elaroussi et al, 2007). In the present study our results reveal that a combination between vitamin E and insulin play a great role in ameliorating the lipid profile in the treated group in comparison with the fatty liver induced group (Table 1) Also, as several cytokines as well as ER stress (Kammoun et al, 2009) are involved in NAFLD fibrogenesis, they may represent potential targets (Albanis et al, 2006).…”

The ameliorating role of vitamin E against iron overload-induced oxidative stress in rats

“…The therapeutic use of antioxidant vitamins has gained considerable interest during the last decade. Previous animal and human studies showed that vitamin E might play an important role in preventing the oxidation of polyunsaturated fatty acids in erythrocytes membrane, thereby maintaining erythrocytes membrane integrity and inhibiting oxidative stress which leads to erythrocytes lysis [41] . Additionally, vitamin E was known to be the most effective natural lipid soluble chain-breaking antioxidant which scavenges free radicals, thereby preventing free radicals generation and reduce lipid peroxidation in erythrocytes membrane, resulting in decreased erythrocytes hemolysis and normalization of all hematological parameters [42] .…”

Hematological and Reproductive Parameters of the Quails Under Inflluence of Amino Acids and Vitamin E Complexes

“…Проте відмічено тенденцію до зменшення кількості лейкоцитів у крові пе-репілок у період статевого дозрівання (40-ва доба) та збільшення на початку яйцекладки, що підтверджує дані Elaroussi [20], який вважає, що такі зміни пов'язані з яєчною продуктивністю перепілок.…”