Effects of Various Antiseptics on Bacteremia Following Tooth Extraction.

Abstract

The effect of local irrigation of the gingival sulcus, which is considered an important source of bacteremia following dental procedures, with three different antiseptic solutions including hydrogen peroxide, chlorhexidine and povidone iodine, on the frequency of bacteremia after tooth extraction was determined, and the efficacies of the three antiseptics were compared. Although all the antiseptic solutions reduced the frequency of bacteremia to various degrees, povidone iodine was the most effective, and seemed to be the best choice since the decrease was statistically significant. Local administration of antiseptic solutions is therefore recommended as an adjuvant to systemic antibiotic prophylaxis.

Preoperative antiseptics in clean/contaminated maxillofacial and oral surgery: prospective randomized study

“…The authors conclude that this antiseptic is very effective in reducing oral cavity bacterial counts up to 1 hour from the start of operation, which makes it suitable for shorter procedures (oral surgery in local anaesthesia). These results are supported by several smaller studies 1,7,21,23,36 . The authors also noticed that its favourable organo-leptic qualities are important when the oral cavity is preoperatively washed in awake patient.…”

Microbiology of Odontogenic Bacteremia: beyond Endocarditis

“…Moreover, broad-spectrum degerming rinses, such as povidone-iodine, chloramine-T, and chlorhexidine, have been shown to reduce the incidence of bacteremia when administered as a rinse or irrigation prior to the extraction procedure or instrumentation, and povidoneiodine was shown to be the most potent in reducing the incidence (84,121,127,144).…”

Selection of antimicrobial agents in periodontal therapy

“…Povidone‐iodine mouthrinse/gargle has shown a reduction in gingival surface bacteria by about 33% compared to 8% by the control solution (47). Also, subgingival irrigation with povidone‐iodine prior to tooth extraction has reduced the incidence of bacteremia by 30–50%(36, 38, 48–53), although not in all studies (54). The American Heart Association has suggested that antiseptic mouthrinses such as povidone‐iodine applied immediately prior to dental procedures might reduce the incidence or magnitude of bacteremia (55).…”