Effects of UV Radiation on Oxidative Stress in Yellowtail Clownfish Amphiprion clarkii

Ryu, Han Seok; Choi, Cheol Young; Song, Jin Ah; Kil, Gyung‐Suk

doi:10.1007/s12601-019-0010-1

Cited by 7 publications

(9 citation statements)

References 23 publications

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“…When DNA is irradiated by UV lights, energy from the photon induces the formation of covalent linkages between adjacent pyrimidine bases, generating cyclobutane pyrimidine dimers (CPDs), and pyrimidine 6-4 pyrimidone photoproducts (6-4 PPs) to break DNA stands ( Rastogi et al, 2010 ). If unrepaired, the broken stands inhibit DNA replication and transcription, which in turn, not only retard cell growth and development ( Hollósy, 2002 ), increase apoptosis ( Ryu et al, 2019 ), but also may result in mutations ( Lahari et al, 2018 ), and further development of various diseases in human ( Sivamani et al, 2009 ). In pathogens, cumulative UV damage adversely influences their pathogenicity ( Milo-Cochavi et al, 2019 ).…”

Section: Introductionmentioning

confidence: 99%

Single Amino Acid Substitution in the DNA Repairing Gene Radiation-Sensitive 4 Contributes to Ultraviolet Tolerance of a Plant Pathogen

Wang

Yang²,

Feng³

et al. 2022

Front. Microbiol.

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To successfully survive and reproduce, all species constantly modify the structure and expression of their genomes to cope with changing environmental conditions including ultraviolet (UV) radiation. Thus, knowledge of species adaptation to environmental changes is a central theme of evolutionary studies which could have important implication for disease management and social-ecological sustainability in the future but is generally insufficient. Here, we investigated the evolution of UV adaptation in organisms by population genetic analysis of sequence structure, physiochemistry, transcription, and fitness variation in the radiation-sensitive 4 (RAD4) gene of the Irish potato famine pathogen Phytophthora infestans sampled from various altitudes. We found that RAD4 is a key gene determining the resistance of the pathogen to UV stress as indicated by strong phenotype-genotype-geography associations and upregulated transcription after UV exposure. We also found conserved evolution in the RAD4 gene. Only five nucleotide haplotypes corresponding to three protein isoforms generated by point mutations were detected in the 140 sequences analyzed and the mutations were constrained to the N-terminal domain of the protein. Physiochemical changes associated with non-synonymous mutations generate severe fitness penalty to mutants, which are purged out by natural selection, leading to the conserved evolution observed in the gene.

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Section: Introductionmentioning

confidence: 99%

Single Amino Acid Substitution in the DNA Repairing Gene Radiation-Sensitive 4 Contributes to Ultraviolet Tolerance of a Plant Pathogen

Wang

Yang²,

Feng³

et al. 2022

Front. Microbiol.

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“…UV radiation (0.4 W/m2) increased apoptosis and reactive oxygen species enzymes (Ryu, Choi, Song, and Kil, 2019). High sensitivity to cyanide, no survival after a 60-second dose of 50 mgL -1 (Madeira et al 2020b).…”

Section: Local Stressorsmentioning

confidence: 98%

“…Transcriptome analysis and/or results from quantitative real-time polymerase chain reaction (qRT-PCR) experiments have yielded insights into changes in gene expression levels under different environmental contexts that pertain to anemonefish development (e.g., embryogenesis, larval metamorphosis, sex change) Schalm et al 2021) and adaptive responses towards external stressors (e.g., pollutants, social stress, oxidative stress) (Ryu et al 2019;Khamkaew et al 2020;. A wealth of transcriptomic sequences is available for multiple tissue and organ samples taken from multiple anemonefish species and reproductive/developmental states, including for different colored skin, the brain, gonads, gill, and retina (see Table 5.1 for a detailed summary of assembled transcriptomes).…”

Section: Insights From Comparative Transcriptomics and Genomicsmentioning

confidence: 99%

Evolution, Development and Ecology of Anemonefishes

Laudet¹,

Ravasi²

2022

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Anemonefishes, one of the most popular and recognizable fishes in the world, are much more than film characters; they are also emerging model organisms for studying the biology, ecology, and evolution of coral reef fishes. They are a group of 28 species often employed to study patterns and processes of social organization, intra-and inter-specific competition, sex change, mutualism, dispersal and connectivity of fish populations, habitat selection, pigment pattern formation, lifespan, and predator-prey interactions. This multi-authored book covers all these areas and provides an update on the research done with this model and the perspective it opens for the future. Key Features• Contains basic and up-to-date information on an emerging fish model • Allows non-specialist readers to grasp the relevance of a wide research area Cover photo: OIST/Kina Hayashi 林希奈 Licensed under CCBY4.0 (attribution) First edition published 2023 by CRC Press

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“…76 In anemonefish, transcriptome sequencing and qPCR experiments have provided insights into gene expression changes during development 12,15,74,[77][78][79][80][81] and adaptive responses to variations in the environment. 21,[82][83][84] Numerous efforts have contributed to the paramount abundance of transcriptomic data that is currently available for different tissues from multiple species and developmental stages (reviewed in Ref. 85), which has enabled the study of specific genes involved in a variety of functions including pigmentation, 15,86 vision, 59,87 thyroid hormone regulation of metabolism, 77 and sex change.…”

Section: Insights From Comparative Transcriptomicsmentioning

confidence: 99%

“…Finally, research has also examined changes in gene expression under different environmental stressors. 21,[82][83][84] Experiments using qPCR analyses have revealed the differential expression of genes strongly correlated to oxidative stress resulting from UV radiation 83 and exposure to bisphenol A (BPA). 84 This last study proposed the use of cytochrome P450 1A gene (cyp1a) as a biomarker for monitoring BPA pollution.…”

Section: Insights From Comparative Transcriptomicsmentioning

confidence: 99%

Anemonefishes: A model system for evolutionary genomics

Herrera

Ravasi²,

Laudet³

2023

F1000Res

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Anemonefishes are an iconic group of coral reef fish particularly known for their mutualistic relationship with sea anemones. This mutualism is especially intriguing as it likely prompted the rapid diversification of anemonefish. Understanding the genomic architecture underlying this process has indeed become one of the holy grails of evolutionary research in these fishes. Recently, anemonefishes have also been used as a model system to study the molecular basis of highly complex traits such as color patterning, social sex change, larval dispersal and life span. Extensive genomic resources including several high-quality reference genomes, a linkage map, and various genetic tools have indeed enabled the identification of genomic features controlling some of these fascinating attributes, but also provided insights into the molecular mechanisms underlying adaptive responses to changing environments. Here, we review the latest findings and new avenues of research that have led to this group of fish being regarded as a model for evolutionary genomics.

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Effects of UV Radiation on Oxidative Stress in Yellowtail Clownfish Amphiprion clarkii

Cited by 7 publications

References 23 publications

Single Amino Acid Substitution in the DNA Repairing Gene Radiation-Sensitive 4 Contributes to Ultraviolet Tolerance of a Plant Pathogen

Single Amino Acid Substitution in the DNA Repairing Gene Radiation-Sensitive 4 Contributes to Ultraviolet Tolerance of a Plant Pathogen

Evolution, Development and Ecology of Anemonefishes

Anemonefishes: A model system for evolutionary genomics

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