Effects of two PBDE congeners on the moulting enzymes of the freshwater amphipod Gammarus pulex

Gismondi, Éric; Thomé, Jean-Pierre

doi:10.1016/j.envpol.2014.04.017

Cited by 30 publications

(14 citation statements)

References 45 publications

(52 reference statements)

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“…Unfortunately, the release of PBDEs in ecosystems continues due to their presence in products currently in use and new products manufactured using recycled PBDE-containing material (La Guardia et al 2006). It has been shown that PBDEs, especially BDE-47 and BDE-99 congeners, bioaccumulated in several aquatic organisms such as fish or bivalves (Gustafsson et al 1999;Lema et al 2007;, but also amphipod (Tlili et al 2012;Gismondi and Thomé 2014;Lebrun et al 2014). Despite these observations, only few studies have investigated PBDEs toxic effects on invertebrates.…”

Section: Introductionmentioning

confidence: 99%

“…is a suitable organism for ecotoxicological assessment of environmental pollutants at a large scale because they are present in most rivers in Europe (Ja_ zd_ zewski 1980). In addition, many ecotoxicological studies have been conducted with gammarids as model to evaluate pollutants impacts (Leroy et al 2010;Gismondi et al 2013;Gismondi and Thomé 2014;Lebrun et al 2014), and some antitoxic defences have been developed in Gammarus sp. as biomarkers (Geffard et al 2007;Lacaze et al 2011;Sroda and Cossu-Leguille 2011;Gismondi et al 2012).…”

Section: Introductionmentioning

confidence: 99%

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Changes in antitoxic defense systems of the freshwater amphipod Gammarus pulex exposed to BDE-47 and BDE-99

2015

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Polybrominated diphenyl ethers (PBDEs) are emerging pollutants widely distributed in aquatic environment. Although the bioaccumulation of this compound has been well studied, few studies have investigated their impacts on antitoxic systems of invertebrates, considering both genders. Here, we have evaluated the effects of BDE-47 and BDE-99 congeners on the antitoxic defence systems of the freshwater amphipod Gammarus pulex, and especially on the multixenobiotic resistance (MXR) activity, as well as the activities of two antitoxic enzymes, the glutathione-S-transferase (GST) and the glutathione peroxidases (GPx). Results revealed that BDE-47 and BDE-99 have inhibited the MXR activity whatever the gammarid gender, which could lead to a reduction of the pollutant elimination from the organism. In addition, a gender-biased response and a congener-biased effect on the antitoxic enzymes activities were observed. Indeed, both BDE congener exposures increased the GST activity in males, whereas in females, only BDE-99 congener modified this activity by decreasing it. On the contrary, BDE exposures did not impact the GPx activity in females, while in males BDE-99 has increased it. Results of the present study highlight that a PBDE exposure at 0.1 lg L -1 modify antitoxic enzymes activities differently according to gender, which could lead to a change in G. pulex sensitivity on the long term. Finally, this work confirms the ecotoxicological implication of gender in the pollutant toxicity assessment, in order to evaluate impact on populations.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Changes in antitoxic defense systems of the freshwater amphipod Gammarus pulex exposed to BDE-47 and BDE-99

2015

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“…Snyder and Mulder (2001) have also suggested that the delay in the beginning of molting of larvae in the lobster H. americanus when exposed to heptachlor, probably correlated to a drop in the concentrations of circulating ecdysteroids. Moreover, knowing that crustacean reproduction is linked to the molt cycle (Hyne, 2011), disruption in the molting process could also cause disturbances in reproduction as hypothesized by Gismondi and Thomé (2014) in the amphipod, G. pulex. Indeed, it was observed that the anti-ecdysteroidal activity of nonylphenol caused a reduction in fecundity of many insects (LeBlanc et al, 2000).…”

Section: Chlordecone Effects On the 20-he Concentrationmentioning

confidence: 99%

“…Indeed, Zou and Fingerman (1999c) observed that some estrogenic agents, such as Aroclor 1242, diethylstilbestrol or endosulfan, inhibited chitobiase activity of the crustacean Uca pugilator. Similarly, Gismondi and Thomé (2014) noted that some pollutants, suspected of being EDCs (i.e. polybromodiphenyl ethers), could disturb the chitobiase activity of the amphipod Gammarus pulex.…”

Section: Introductionmentioning

confidence: 99%

Effects of chlordecone on 20-hydroxyecdysone concentration and chitobiase activity in a decapod crustacean, Macrobrachium rosenbergii

et al. 2016

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a b s t r a c tChlordecone (CLD) is an organochlorine insecticide abundant in aquatic environment of the French West Indies. However, few studies have investigated its impact on freshwater invertebrates. Whereas CLD is suspected of inducing endocrine disruption, this work aimed to study the effects of environmentally relevant concentrations of CLD on the 20-hydroxyecdysone (20-HE) hormone concentration and on the chitobiase activity, both having key roles in the molting process of crustaceans. In addition, the bioaccumulation of CLD was measured in the muscle tissue of Macrobrachium rosenbergii to underline potential dose-response relationship. The results have shown that CLD was bioaccumulated in exposed organisms according to a trend to a dose-response relationship. Moreover, it was observed that CLD decreased the 20-HE concentration in exposed prawns when compared to control, whatever the duration of exposure, as well as it inhibited the chitobiase activity after 30 days of exposure. The present study indicates that CLD could interfere with molting process of M. rosenbergii by disturbing the 20-HE concentration and the activity of chitobiase, suggesting consequences at the long term on the shrimp development. This study also confirmed that CLD could be an endocrine disruptor in decapod crustaceans, as it was already observed in vertebrates.

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“…Studies on the impacts of endocrine-disrupting compounds (EDCs) on wildlife have focused mainly on hormonal regulation related to reproduction and development processes which have critical roles in population dynamics (Arukwe and Goksøyr 2003;Gismondi and Thomé 2014;Jubeaux et al 2012). Indeed, many pollutants in aquatic environment are able to interfere with the endocrine system of exposed organisms which could lead to dysfunctions of biological processes (e.g., growth, reproduction) (Hyne 2011).…”

Section: Introductionmentioning

confidence: 99%

Vitellogenin and vitellogenin receptor gene expression and 20-hydroxyecdysone concentration in Macrobrachium rosenbergii exposed to chlordecone

Lafontaine

Hanikenne

Boulangé-Lecomte

et al. 2016

Environ Sci Pollut Res

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Chlordecone is a persistent organochlorine pesticide widely used in Guadeloupe (French West Indies) to control the banana weevil Cosmopolites sordidus. Although it was previously highlighted that chlordecone may affect the reproduction and growth of vertebrate species, little information is available on the chlordecone effects in invertebrates. The present study investigated the effects of chlordecone on a hormone and a protein having key roles in reproduction and growth of the decapod crustacean Macrobrachium rosenbergii, by measuring the 20-hydroxyecdysone concentration, vitellogenin, and vitellogenin receptor gene expression, as well as the bioconcentration of chlordecone in exposed prawns. First, the results revealed that chlordecone was accumulated in M. rosenbergii. Then, it was found that Vg and VgR gene expression were increased in male and female M. rosenbergii exposed to chlordecone for 90 and 240 days, while the 20-hydroxyecdysone concentrations were decreased. This work suggests that chlordecone accumulates in prawn tissues and could affect key molecules involved in the reproduction and the growth of the invertebrate M. rosenbergii. However, many questions remain unresolved regarding the impacts of chlordecone on growth and reproduction and the signaling pathways responsible for these effects, as well as the potential role of confounding factors present in in situ studies.

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Effects of two PBDE congeners on the moulting enzymes of the freshwater amphipod Gammarus pulex

Cited by 30 publications

References 45 publications

Changes in antitoxic defense systems of the freshwater amphipod Gammarus pulex exposed to BDE-47 and BDE-99

Changes in antitoxic defense systems of the freshwater amphipod Gammarus pulex exposed to BDE-47 and BDE-99

Effects of chlordecone on 20-hydroxyecdysone concentration and chitobiase activity in a decapod crustacean, Macrobrachium rosenbergii

Vitellogenin and vitellogenin receptor gene expression and 20-hydroxyecdysone concentration in Macrobrachium rosenbergii exposed to chlordecone

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