“…Likewise, mussels respond to pollution and other environmental stress sources in a way that can be measured through biological effect biomarkers; that is why they are widely used as sentinels in coastal ecosystem health assessment (UNEP/RAMOGE, 1999;ICES, 2012;Marigómez et al, 2013a). Besides, recent investigations have reported interactive effects of either elevated temperature or heat-shock with pollution (Sokolova, 2004;Baines et al, 2006;Lannig et al, 2006a,b;Sokolova and Lannig, 2008;Ivanina et al, 2009;Negri et al, 2013;Izagirre et al, 2014;Múgica et al, 2015).…”