Effects of supervised chlorhexidine mouthrinses in children

Lang, Niklaus P.; Hotz, P; Graf, H.; Geering, Alfred H.; Saxer, Ulrich; Sturzenberger, O. P.; Meckel, A. H.

doi:10.1111/j.1600-0765.1982.tb01135.x

Cited by 165 publications

(115 citation statements)

References 20 publications

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“…Side effects have been reported after the utilization of chlorhexidine, specially regarding its bitter taste. The presence of dental pigmentation in groups II and III confirms this side effect as the most frequently detected in the majority of the studies on chlorhexidine, in adults and children 11,21 . Disregarding the alteration observed in these two groups, no irritation or desquamation of the oral mucosa were observed, neither were burning or dryness symptoms reported.…”

Section: Discussionsupporting

confidence: 70%

“…In addition, it has already been demonstrated that mouthrinses with chlorhexidine, in different concentrations, frequencies of use, and quantities, prevent the formation of dental plaque 11,15 . Employing the same rou- tine as that carried out in group II during 6 weeks, Zanela 21 (1995) observed a reduction of 52.63% in the mean score of plaque, which is in agreement with the findings of the present study.…”

Section: Discussionmentioning

confidence: 99%

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The influence of mouthrinses with antimicrobial solutions on the inhibition of dental plaque and on the levels of mutans streptococci in children

Zanela

Bijella

Rosa

2002

Pesqui. Odontol. Bras.

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The effect of daily mouthrinses on dental plaque accumulation and on salivary mutans streptococci was investigated in 200 children. The utilized solutions were: a placebo solution composed of mentholated deionized water (group I); 0.12% chlorhexidine gluconate associated to 0.05% sodium fluoride (group II); 0.2% chlorhexidine digluconate (group III), and 0.5% stevioside mixed with 0.05% sodium fluoride, with pH 3.4 (group IV). In order to verify the effect on plaque formation, the accumulation of plaque was assessed by means of the Löe12 index, at the beginning and at the end of the experiment, whereas the quantification of cariogenic streptococci was accomplished on three saliva samples collected at 3 different moments: before the first mouthrinse, 24 hours after the first mouthrinse and 1 week after the last mouthrinse. The mouthrinsing routine was carried out on a daily basis during 4 weeks. Five milliliters of solution were rinsed during 1 minute. The results revealed 4.10, 26.75, 41.20, and 5.91% of reduction in plaque accumulation for groups I, II, III, and IV, respectively. Comparisons between the groups as to plaque reduction revealed that groups II and III were significantly different from groups I (control) and IV (p < 0.05), but did not differ from each other. The solution utilized by group III was the least accepted by children and, as the solution utilized by group II, caused mild dental pigmentation. There were no statistically significant differences as to the levels of mutans streptococci, probably due to the low initial levels observed in each one of the four groups.

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Section: Discussionsupporting

confidence: 70%

Section: Discussionmentioning

confidence: 99%

The influence of mouthrinses with antimicrobial solutions on the inhibition of dental plaque and on the levels of mutans streptococci in children

Zanela

Bijella

Rosa

2002

Pesqui. Odontol. Bras.

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“…Concentrations of 0.12 or 0.2% CHX mouthwash significantly reduce plaque and gingivitis. [21][22][23] The antibacterial properties of these products have been demonstrated in vitro as well as in vivo. 24,25 The studies comparing CHX with other active agents such essential oils, sanguinarine, and delmopinol provide enough evidence on the superiority of CHX.…”

Section: Chlorhexidine (Chx)mentioning

confidence: 99%

Chemical Plaque Control Strategies in the Prevention of Biofilm-associated Oral Diseases

Jafer

Patil

Hosmani

et al. 2016

The Journal of Contemporary Dental Practice

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Dental plaque is a biofilm that forms naturally on the surfaces of exposed teeth and other areas of the oral cavity. It is the primary etiological factor for the most frequently occurring oral diseases, such as dental caries and periodontal diseases. Specific, nonspecific, and ecologic plaque hypothesis explains the causation of dental and associated diseases. Adequate control of biofilm accumulation on teeth has been the cornerstone of prevention of periodontitis and dental caries. Mechanical plaque control is the mainstay for prevention of oral diseases, but it requires patient cooperation and motivation; therefore, chemical plaque control agents act as useful adjuvants for achieving the desired results. Hence, it is imperative for the clinicians to update their knowledge in chemical antiplaque agents and other developments for the effective management of plaque biofilm-associated diseases. This article explores the critical analysis of various chemical plaque control strategies and the current trends in the control and prevention of dental plaque biofilm.

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“…6 A lower concentration of CHX (0.12%) has been tested in animals and human populations and has also demonstrated clinical benefits. 7,13,14 Although CHX is an effective antimicrobial agent in both concentrations, comparison of the two existing formulations is still necessary. The aim of the present study was to assess the efficacy of two concentrations of chlorhexidine solutions (0.12% and 0.20%) on plaque development and gingival bleeding control during 14 days.…”

mentioning

confidence: 99%

Comparative analysis of the effect of two chlorhexidine mouthrinses on plaque accumulation and gingival bleeding

Neto¹,

Parolo²,

Rösing

et al. 2008

Braz. oral res.

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The aim of the present study was to evaluate the effect of two chlorhexidine rinsing solutions (0.12% and 0.2%) on plaque and gingival bleeding. Ten dental students participated in this double-blind, cross-over study, rinsing twice a day, for one minute, with each one of the tested solutions for fourteen days. A wash-out period of one week between treatments was observed. In order to assess gingival bleeding, the van der Weijden et al. 1 (1994) index was used. The plaque indexes used were those of Quigley, Hein 2 (1962) and Silness, Löe 3 (1964). In the pre-experimental period, subjects received oral hygiene instructions and dental prophylaxis. The results revealed no significant differences between both concentrations in relation to plaque and gingival bleeding. Mean values (± standard deviation) of the Quigley & Hein index were 0.25 ± 0.16 for the 0.12% solution and 0.23 ± 0.26 for the 0.2% solution (p = 0.4838). Mean values (± standard deviation) of the Silness-Löe index were 0.12 ± 0.10 for the 0.12% solution and 0.11 ± 0.11 for the 0.2% solution (p = 0.7592). The bleeding index mean values at the end of the study were not different for both concentrations with mean values (± standard deviation) of 14.93% ± 6.68% and 13.95 ± 9.24% for the 0.12% and 0.2% solutions, respectively. Although an increase in gingival bleeding was observed, both concentrations were able to control dental plaque.

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Effects of supervised chlorhexidine mouthrinses in children

Cited by 165 publications

References 20 publications

The influence of mouthrinses with antimicrobial solutions on the inhibition of dental plaque and on the levels of mutans streptococci in children

The influence of mouthrinses with antimicrobial solutions on the inhibition of dental plaque and on the levels of mutans streptococci in children

Chemical Plaque Control Strategies in the Prevention of Biofilm-associated Oral Diseases

Comparative analysis of the effect of two chlorhexidine mouthrinses on plaque accumulation and gingival bleeding

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