Chemical Plaque Control Strategies in the Prevention of Biofilm-associated Oral Diseases

Abstract

Dental plaque is a biofilm that forms naturally on the surfaces of exposed teeth and other areas of the oral cavity. It is the primary etiological factor for the most frequently occurring oral diseases, such as dental caries and periodontal diseases. Specific, nonspecific, and ecologic plaque hypothesis explains the causation of dental and associated diseases. Adequate control of biofilm accumulation on teeth has been the cornerstone of prevention of periodontitis and dental caries. Mechanical plaque control is the mainstay for prevention of oral diseases, but it requires patient cooperation and motivation; therefore, chemical plaque control agents act as useful adjuvants for achieving the desired results. Hence, it is imperative for the clinicians to update their knowledge in chemical antiplaque agents and other developments for the effective management of plaque biofilm-associated diseases. This article explores the critical analysis of various chemical plaque control strategies and the current trends in the control and prevention of dental plaque biofilm.

Actividad antimicrobiana in vitro del camu camu (Myrciaria dubia) contra microorganismos orales: una revisión sistemática

“…Esto indica la necesidad de estudiarlo más en el ámbito odontológico y así poder medir su actividad antimicrobiana versus antisépticos orales convencionales. Cabe mencionar que existen revisiones de literatura de M. dubia (56,23,57) , pero esta es la primera revisión sistemática que evalúa su actividad antimicrobiana contra microorganismos de la cavidad oral.…”

“…El adecuado control mecánico de la acumulación de PD en dientes ha sido la piedra angular para prevenir dichas enfermedades, pero requiere de una inmensa cooperación y motivación del paciente. Por lo tanto, los agentes químicos actúan como útiles complementos para lograr un manejo efectivo de la placa dental asociada a CD y EP (23) . En consecuencia, el objetivo del presente estudio tuvo como objetivo evaluar la actividad antimicrobiana in vitro de M. dubia contra microorganismos orales.…”

The Inhibitory Activity of Anthraquinones against Pathogenic Protozoa, Bacteria, and Fungi and the Relationship to Structure

“…Interest in anthraquinones arises from the fact that they are reported to have multiple potential health benefits in cells and in vivo, including antibiotic [ 1 , 4 , 7 , 8 ], anticancer [ 2 , 9 , 10 , 11 ], antidiabetic [ 4 ], antifungal [ 12 ], anti-inflammatory [ 13 ], anti-obesity [ 14 ], antioxidative [ 13 , 15 ], antiprotozoal [ 16 , 17 , 18 ], antiviral [ 19 ], cardioprotective [ 20 ], hepatoprotective [ 21 ], and neuroprotective [ 22 ] properties. Emodin and aloe-emodin are already widely used as stimulant laxatives sold in pharmacies to treat constipation [ 6 , 23 , 24 ].…”

Antimicrobial Effect of Newly Formulated Toothpastes and a Mouthrinse on Specific Microorganisms: An In Vitro Study

“…The most effective measure for the prevention of plaque formation is the mechanical removal of dental plaque by regular tooth brushing, but its efficacy is highly dependent on the ability and cooperation of the individual. 8 9 Therefore, chemical plaque control agents such as toothpastes and mouthrinse should be used due to their potential role as a delivery system for antimicrobials. 9 10 Various chemical agents such as triclosan, chlorhexidine (CHX), metal ions, and essential oils have been added to toothpastes and mouthrinse to provide antimicrobial activity.…”