1991
DOI: 10.1007/bf01649051
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Effects of subclinical hyperthyroidism on renal handling of water and electrolytes in patients with nodular goiter

Abstract: Evidence is beginning to accumulate that minor degrees of hyperthyroidism lead to adverse effects in various tissues, even though clinically the patients are euthyroid. To determine whether these anomalies in thyroid function have deleterious effects on renal function and electrolyte metabolism, the plasma concentrations of electrolytes, urea, and creatinine, the renal handling of water and sodium, and the urinary excretion of these substances were measured in patients with nodular goiter who were displaying s… Show more

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Cited by 7 publications
(4 citation statements)
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“…Although, in overt hyperthyroidism, the enhanced tubular reabsorption of sodium due to increased activity of Na+/H+ exchanger in combination with the decreased load of filtered sodium causes a decrease in the pressure-diuresis-natriuresis response [ 30 ], we did not find a significant difference in electrolytes whether in blood or urine among SCH patients. This is consistent with a previous study that compared patients with SCH and euthyroidism regarding the mean plasma levels of electrolytes and did not reveal any significant differences [ 31 ].…”
Section: Discussionsupporting
confidence: 93%
“…Although, in overt hyperthyroidism, the enhanced tubular reabsorption of sodium due to increased activity of Na+/H+ exchanger in combination with the decreased load of filtered sodium causes a decrease in the pressure-diuresis-natriuresis response [ 30 ], we did not find a significant difference in electrolytes whether in blood or urine among SCH patients. This is consistent with a previous study that compared patients with SCH and euthyroidism regarding the mean plasma levels of electrolytes and did not reveal any significant differences [ 31 ].…”
Section: Discussionsupporting
confidence: 93%
“…Thyroid hormones and TSH concentrations were measured in the serum of all patients by RIA and by an amplified immunoradiometric assay (for TSH), according to previously described techniques (Corrales et al 1991, Mories et al 1991. For the determination of serum TBII concentrations, the ability of antibodies to block the binding of 125 I-labelled TSH to porcine thyroid membranes was measured by a radioreceptor assay using a commercial kit (TRAK-Assay, Henning, Berlin, Germany).…”
Section: Thyroid Hormones and Autoantibodiesmentioning
confidence: 99%
“…Thyroid hormones and TSH levels were measured in the serum of all patients by RIA and by an amplified immunoradiometric assay (for TSH), according to previously described techniques (4,20). For the determination of serum TBII levels, a radioreceptor assay that measures the occupancy of TSH receptor was used (TRAK-Assay, Henning, Berlin, Germany).…”
Section: Thyroid Hormones Anti-tsh Receptor Antibodiesmentioning
confidence: 99%