Effects of Storage of Blood at Room Temperature on Hematologic Parameters Measured on Sysmex XE-2100

Evaluation and Comparison of Stability and Reliability of CBC Parameters Determined by Using Automatic Celltac G MEK-9100 Hematology Analyzer during Extended Storage at 4°C

“…Result of MCV was found to be stable up to 42 h, regarding result for MCV at 4°C, previous studies are also show supporting with our findings [5,6,15,20,21]. Studies by Turhan et al [5] and Lippi et al [2] demonstrated increment was observed on the second day due to reflect the swelling of RBC at room temperature.…”

“…Studies of Baca et al [21] Muller et al [23] and A. Joshi et al [15] show a stability time of 48 h to 72 h which is not much different from our findings. Demonstrated by Hedberg et al [20] and Muller et al [23] slight decrease in neutrophils at 4°C during 48 h to 72 h is identical to our result.…”

“…The conclusion of these parameters is identical investigated by Monica Ed Baca et al [21] room temperature using Sysmex X-2100 and Sven christen Voss et al [25] at 4°C.…”

“…Improved stability was observed in samples stored as K2-EDTA-anticogulated blood sample at refrigeration [5,9,10,[17][18][19]. Significant time and temperature related morphological alterations could happen with the long extended storage of blood on refrigeration (Figure 1) [17,20,21].…”

“…However, some studies, which were conducted using refrigerated temperature show that WBC, RBC, and HGB parameters, were constant up to 72 h [21,22]. Only Ashenden et al recently confirmed that haemoglobin was stable for at least 168 h using the Sysmex XT-2000i instrument, when maintained temperature between 4°C and 6°C [18].…”