Effects of Storage of Blood at Room Temperature on Hematologic Parameters Measured on Sysmex XE-2100

Baca, Monica E. de; Gulati, Gene; Kocher, William; Schwarting, Roland

doi:10.1309/1eer-k1m0-2qfj-rx6p

Cited by 4 publications

(14 citation statements)

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“…The trends apparent in Table 3A and Table 3B are consistent with those seen by investigators with the Sysmex XE-2100,2 which is very similar to the Sysmex XT series instruments in technology and operation. These results are also consistent with limited unpublished studies on sample stability with the Sysmex XT-2000i available from Sysmex America.…”

Section: Resultssupporting

confidence: 84%

Evaluation of the Performance of the Sysmex XT-2000i Hematology Analyzer With Whole Blood Specimens Stored at Room Temperature

Hill

Simpson

Higgins

et al. 2009

Lab Med

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Section: Resultssupporting

confidence: 84%

Evaluation of the Performance of the Sysmex XT-2000i Hematology Analyzer With Whole Blood Specimens Stored at Room Temperature

Hill

Simpson

Higgins

et al. 2009

Lab Med

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“…Although, taurine was found to exert stabilizing effects on PLT and RBC counts, it did not stabilize the mean volumes of these blood components, the MPV and MCV, respectively, as have been observed elsewhere (6,7,15,16) . This may be attributed to the preservation of structural integrity of their membranes by taurine but not the functional transport across the membrane which seems to be independent of the action of taurine.…”

Section: Discussionmentioning

confidence: 46%

“…Significant time-and temperature-dependent morphological changes can occur with the prolonged storage of blood (6,7,13,15,16) . The CBC as well as blood smears should be processed as quickly as possible after collection to avoid normal degenerative changes in blood cell morphology, which are mainly due to weakness in controlling cell membrane integrity, and consequently changing cell volume and related indices.…”

Section: Discussionmentioning

confidence: 99%

“…Currently, most clinical laboratories are equipped with modern automated analyzers that are capable of processing a large number of hematological tests in an efficient and timely manner (1,2) . However, for reliable results, it is essential that specimens are collected properly and in the right anticoagulant and then examined in a calibrated analyzer within a specified time frame according to the manufacturer instructions (3-6) . …”

Section: Introductionmentioning

confidence: 99%

“…Moreover, at weekends, this interval may exceed 36 hours. Therefore, when such specimens arrive in the laboratory, technicians must decide on whether to accept or refuse the processing of the specimens (6) . Although laboratories should maintain the consistency of results, disproportionate delays in processing might affect the reliability of results (7) .…”

Section: Introductionmentioning

confidence: 99%

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Effect of the addition of the antioxidant taurine on the complete blood count of whole blood stored at room temperature and at 4°C for up to 7 days

Sirdah¹,

Abushahla²,

Al-Sarraj³

2013

Revista Brasileira De Hematologia E Hemoterapia

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BackgroundThe complete blood count is one of the most common routine tests. This study aimed to evaluate possible effects of the antioxidant taurine on the complete blood count of whole blood stored at room temperature and at 4ºC over seven days. MethodsVenous blood samples of 25 healthy males were distributed into two sets of tubes with each set of four tubes containing 50 µL of solutions with zero, 2.5 g/L, 5 g/L, 10 g/L taurine. The tubes were kept at room temperature or at 4ºC. Complete blood counts were performed on seven successive days. The mean percentage changes [Δ = (mean value - mean baseline value) / mean baseline value x 100] were calculated and compared. ResultsComplete blood count parameters exhibited different patterns of behavior which were affected by the storage temperature, time and taurine concentration. Taurine at room temperature significantly enhanced the stability of: the platelet count over seven days (Δ7 at 2.5, 5 and 10 g/L taurine were 5.45, 6.11, and 5.80 x 109 cells/L, respectively); the red blood cell count over five days (Δ5 at 2.5, 5 and 10 g/L taurine were 1.59, 2.79, and 1.98 x 1012 cells/L, respectively); mean corpuscular hemoglobin over five days (Δ5 at 2.5, 5 and 10 g/L taurine were -0.91,-1.52 and -0.84 fl respectively); and red cell distribution width over two days (Δ2 at 2.5, 5 and 10 g/L taurine were 0.90%, 1.30% and -0.1%, respectively). No additional stabilizing effects of taurine were reported for the mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, hematocrit and hemoglobin, while it negatively affected the white blood cell stability. ConclusionComplete blood count parameters exhibited variable stability patterns in respect to temperature, time and taurine concentration.

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Determining the stability of complete blood count parameters in stored blood samples using the SYSMEX XE‐5000 automated haematology analyser

Joshi

McVicker

Favaloro

et al. 2015

Int J Lab Hematology

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Effects of Storage of Blood at Room Temperature on Hematologic Parameters Measured on Sysmex XE-2100

Cited by 4 publications

References 0 publications

Evaluation of the Performance of the Sysmex XT-2000i Hematology Analyzer With Whole Blood Specimens Stored at Room Temperature

Evaluation of the Performance of the Sysmex XT-2000i Hematology Analyzer With Whole Blood Specimens Stored at Room Temperature

Effect of the addition of the antioxidant taurine on the complete blood count of whole blood stored at room temperature and at 4°C for up to 7 days

Determining the stability of complete blood count parameters in stored blood samples using the SYSMEX XE‐5000 automated haematology analyser

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