Effects of sterilization methods on key properties of specialty optical fibers used in medical devices

Stolov, Andrei A.; Slyman, Brian E.; Burgess, David; Hokansson, Adam S.; Li, Jie; Allen, R. Steve

doi:10.1117/12.1000005

Cited by 11 publications

(10 citation statements)

References 16 publications

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“…The measurements did not reveal measurable differences between the reference and samples exposed to 34, 85 and 102 Mrad of gamma radiation. This observation is in agreement with a previous study [37].…”

Section: B Experimental Resultssupporting

confidence: 94%

“…Fourier transform infrared (FTIR) spectroscopy analysis of the coatings was carried out using a Thermo Fisher iS50 spectrometer in attenuated total reflection configuration [37]. A germanium internal reflection element was utilized.…”

Section: B Experimental Resultsmentioning

confidence: 99%

“…The fibers may also suffer radiation-induced damage via their coating layers. In one study, the tensile strengths of fibers coated by an ethylene tetrafluoroethylene polymer buffer layer were degraded following gamma irradiation [37,38]. The strength reduction was attributed to the release of hydrogen fluoride from the buffer layer, which corroded and weakened the silica fiber [37,38].…”

Section: Introductionmentioning

confidence: 99%

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Opto-Mechanical Fiber Sensing of Gamma Radiation

London¹,

Sharma

Diamandi

et al. 2021

J. Lightwave Technol.

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The monitoring of ionizing radiation is critical for the safe operation of nuclear and other high-power plants. Fiberoptic sensing of radiation has been pursued for over 45 years. Most protocols rely on radiation effects on the optical properties of the fiber. Here we propose a new concept, in which the opto-mechanics of standard fibers coated by thin layers of fluoroacrylate polymer are observed instead. The time-of-flight of radial acoustic waves through the coating is evaluated by forward stimulated Brillouin scattering measurements. The time-of-flight is seen to decrease monotonically with the overall dosage of gamma radiation from a cobalt source. Variations reach 15% of the initial value for 180 Mrad dose and remain stable for at least several weeks following exposure. The faster times-of-flight are consistent with a radiation-induced increase in the coating stiffness, observed in offline analysis. The effects on the coating are independent of possible changes in the optical parameters of the fiber. The combination of opto-mechanical analysis together with established fiber sensing protocols may help disambiguate the evaluation of multiple radiation metrics and reduce environmental crosssensitivities. The technique is suitable for online monitoring and may be extended to spatially distributed measurements.

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Section: B Experimental Resultssupporting

confidence: 94%

Section: B Experimental Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Opto-Mechanical Fiber Sensing of Gamma Radiation

London¹,

Sharma

Diamandi

et al. 2021

J. Lightwave Technol.

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“…Several factors can affect the mechanical integrity of optical fibers used in biomedical environments. [20][21][22][23] Among these effects are potential strength degradations due to repeated sterilization processes, long-term exposure to UV light, damage to fibers and connectors due to improper handling, and exposure to extremely high optical power levels.…”

Section: Mechanical Propertiesmentioning

confidence: 99%

Review of diverse optical fibers used in biomedical research and clinical practice

et al. 2014

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Abstract. Optical fiber technology has significantly bolstered the growth of photonics applications in basic life sciences research and in biomedical diagnosis, therapy, monitoring, and surgery. The unique operational characteristics of diverse fibers have been exploited to realize advanced biomedical functions in areas such as illumination, imaging, minimally invasive surgery, tissue ablation, biological sensing, and tissue diagnosis. This review paper provides the necessary background to understand how optical fibers function, to describe the various categories of available fibers, and to illustrate how specific fibers are used for selected biomedical photonics applications. Research articles and vendor data sheets were consulted to describe the operational characteristics of conventional and specialty multimode and single-mode solid-core fibers, double-clad fibers, hard-clad silica fibers, conventional hollow-core fibers, photonic crystal fibers, polymer optical fibers, side-emitting and side-firing fibers, middle-infrared fibers, and optical fiber bundles. Representative applications from the recent literature illustrate how various fibers can be utilized in a wide range of biomedical disciplines. In addition to helping researchers refine current experimental setups, the material in this review paper will help conceptualize and develop emerging optical fiber-based diagnostic and analysis tools.

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“…Optical sensors can also be sterilized, without affecting their properties. Stolov et al [ 124 ] demonstrated the possibility of: (i) steam sterilization; (ii) ethylene oxide and (iii) gamma radiation on optical fibres with: (1) dual acrylate; (2) polyimide; (3) silicone polyether ether ketone (PEEK); and (4) fluoroacrylate hard cladding ethylene tetrafluoroethylene (ETFE).…”

Section: Optical Fibre Pressure Sensors In Medicinementioning

confidence: 99%

Optical Fibre Pressure Sensors in Medical Applications

Poeggel

Tosi

Duraibabu

et al. 2015

Sensors

174

102

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This article is focused on reviewing the current state-of-the-art of optical fibre pressure sensors for medical applications. Optical fibres have inherent advantages due to their small size, immunity to electromagnetic interferences and their suitability for remote monitoring and multiplexing. The small dimensions of optical fibre-based pressure sensors, together with being lightweight and flexible, mean that they are minimally invasive for many medical applications and, thus, particularly suited to in vivo measurement. This means that the sensor can be placed directly inside a patient, e.g., for urodynamic and cardiovascular assessment. This paper presents an overview of the recent developments in optical fibre-based pressure measurements with particular reference to these application areas.

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Effects of sterilization methods on key properties of specialty optical fibers used in medical devices

Cited by 11 publications

References 16 publications

Opto-Mechanical Fiber Sensing of Gamma Radiation

Opto-Mechanical Fiber Sensing of Gamma Radiation

Review of diverse optical fibers used in biomedical research and clinical practice

Optical Fibre Pressure Sensors in Medical Applications

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