Effects of Some Lamiaceae Species Methanol Extracts on Potential Mycotoxin Producer Fungi

Aşkun, Tülin; Tümen, Gülendam; Satıl, Fatih; Kılıç, Turgut

doi:10.1080/13880200802215792

Cited by 18 publications

(13 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Masumeh (2006) S. hortensis Abdollahi et al (2010Abdollahi et al ( , 2011Abdollahi et al ( , 2012, Adiguzel et al (2007), Aksu and Ozer (2013), Alizadeh-Salteh et al (2010b), Anghel et al (2013), Askun et al (2008), Azaz et al (2005), Azizi et al (2008), Bouari et al (2011), Boyraz and Ozcan (2006), Deans and Svoboda (1989), Dikbas et al (2008Dikbas et al ( , 2010Dikbas et al ( , 2012, Djenane et al (2011a), Fit et al (2009), Gulluce et al (2003), Gumus (2010), Gursoy et al (2009), Hosseini et al (2013), Karami-Osboo et al (2010), Kiran et al (2010), Kizil and Uyar (2006), Kotan et al (2012Kotan et al ( , 2013, Mahboubi and Kazempour (2009), Mihajilov-Krstev et al (2009a, Nabigol (2011), Nedorostova et al (2011), Oussalah et al (2006b), Ozcan et al (2008), RazzaghiAbyaneh et al (2008), Rezvanpanah et al (2011), Sagdic et al (2010Sagdic et al ( , 2013, Saharkhiz et al (2011), Sahin et al (2003), …”

Section: S Edmondimentioning

confidence: 99%

A pharmacological and phytochemical overview onSatureja

Tepe

Çilkiz

2015

Pharmaceutical Biology

View full text Add to dashboard Cite

Context: Satureja (Lamiaceae) species are used as flavoring compounds in food, pharmaceutical, and cosmetic industries because of its sweetness and simple cultivation characteristics. They have traditionally been used as muscle pain relievers, tonic, and carminative agents to treat stomach and intestinal disorders such as cramps, nausea, indigestion, and diarrhea, due to their considerable phytochemical characteristics. Objective: This review evaluates some information published since 1989 on Satureja genus from a systematic perspective in terms of its pharmacological and phytochemical characteristics. Materials and methods: Web of Science, PubMed, Scopus, and Google Scholar databases were searched up to March 2014. ''Satureja'' was used as a research term without narrowing or limiting research elements. After obtaining all reports from database (a total number is about 637), the papers were carefully analyzed in order to find data related to the topic of this review. Results: In this review, 453 reports were used which were published between 1989 and 2014. The study was compiled into two sections (Pharmacology and Phytochemistry). In the pharmacology section, more than 50 different activities were studied. In the second section, in addition to other compounds and inorganic substances, volatiles, phenolic acids, and flavonoids were discussed. Discussion and conclusion: According to our contemporary information, Satureja species have been evaluated for their wide range of biological activities. However, a small part of these studies have been carried out on the active principles. Therefore, in the future, more studies should be carried out to identify responsible phytochemicals for the various activities.

show abstract

Section: S Edmondimentioning

confidence: 99%

A pharmacological and phytochemical overview onSatureja

Tepe

Çilkiz

2015

Pharmaceutical Biology

View full text Add to dashboard Cite

show abstract

“…The MBC value of 50–100 μg/ml against four tested organism ( Askun et al, 2013 ). Antifungal, antibacterial ( Askun et al, 2008 , De Oliveira et al, 2011 ). Micromeria juliana (L.) Benth.…”

Section: Introductionmentioning

confidence: 99%

A review of medicinal plant of Middle East and North Africa (MENA) region as source in tuberculosis drug discovery

Dehyab

Bakar

AlOmar

et al. 2020

Saudi Journal of Biological Sciences

View full text Add to dashboard Cite

Tuberculosis (TB) is a disease that affects one-third of the world’s population. Although currently available TB drugs have many side effects, such as nausea, headache and gastrointestinal discomfort, no new anti-TB drugs have been produced in the past 30 years. Therefore, the discovery of a new anti-TB agent with minimal or no side effects is urgently needed. Many previous works have reported the effects of medicinal plants against Mycobacterium tuberculosis (MTB). However, none have focused on medicinal plants from the Middle Eastern and North African (MENA) region. This review highlights the effects of medicinal plants from the MENA region on TB. Medicinal plants from the MENA region have been successfully used as traditional medicine and first aid against TB related problems. A total of 184 plants species representing 73 families were studied. Amongst these species, 93 species contained more active compounds with strong anti-MTB activity (crude extracts and/or bioactive compounds with activities of 0–100 µg/ml). The extract of Inula helenium, Khaya senegalensis, Premna odorata and Rosmarinus officinalis presented the strongest anti-MTB activity. In addition, Boswellia papyrifera (Del) Hochst olibanum, Eucalyptus camaldulensis Dehnh leaves (river red gum), Nigella sativa (black cumin) seeds and genus Cymbopogon exhibited anti-TB activity. The most potent bioactive compounds included alantolactone, octyl acetate, 1,8-cineole, thymoquinone, piperitone, α- verbenol, citral b and α-pinene. These compounds affect the permeability of microbial plasma membranes, thus kill the mycobacterium spp. As a conclusion, plant species collected from the MENA region are potential sources of novel drugs against TB.

show abstract

“…They are used as culinary herbs and in folk medicine to treat various ailments, based on their different plant activities. The essential oil isolated from various Satureja species possesses certain biological properties, such as antifungal [ 12 ], antibacterial [ 13 ], anticholinesterase and antioxidant [ 14 ], and anti-HIV-1 [ 15 ] properties.…”

Section: Introductionmentioning

confidence: 99%

Preliminary antimycobacterial study on selected Turkish plants (Lamiaceae) against Mycobacterium tuberculosis and search for some phenolic constituents

Aşkun

Tekwu

Satıl

et al. 2013

BMC Complement Altern Med

View full text Add to dashboard Cite

BackgroundThe global resurgence of tuberculosis is a significant threat. Lamiaceae members have been used in folk remedies for centuries. This study was designed to assess the in-vitro antimycobacterial activity of eighteen crude extracts from six plants (Lamiaceae) and to characterize their phenolic and flavonoid compounds.MethodsSix Turkish medicinal plants of the family Lamiaceae (Stachys tmolea Boiss., Stachys thirkei C. Koch, Ballota acetabulosa (L.) Benth., Thymus sipthorpii Benth., Satureja aintabensis P.H. Davis, and Micromeria juliana (L.) Benth. ex Reich.) were collected in 2009 – 2010. Dried and crushed plant samples were subjected to sequential extraction with petroleum ether, ethyl acetate, and methanol in order of increasing polarity. A broth microdilution method was employed to screen extracts against four mycobacterial strains of Mycobacterium tuberculosis. Phenolic and flavonoid compounds were characterized by liquid chromatography–mass spectrometry.ResultsS. aintabensis, T. sibthorpii, and M. juliana were found to develop considerable activity against the four strains of M. tuberculosis with the minimal inhibitory concentrations value of 12.5-100 μg/ml. S. aintabensis and T. sibthorpii extracts killed M. tuberculosis with the minimum bactericidal concentration value of 50–800 μg/ml. On the basis of these prominent antimycobacterial activity, we suggest that they could be a source of natural anti-tuberculosis agents.ConclusionS. aintabensis and T. sibthorpii showed activity by killing Mycobacteria strains. The major phenolic compound was rosmarinic for T. sibthorpii and S. aintabensis. Flavonoids might be “a modal” for the drug design.

show abstract

Effects of Some Lamiaceae Species Methanol Extracts on Potential Mycotoxin Producer Fungi

Cited by 18 publications

References 33 publications

A pharmacological and phytochemical overview onSatureja

A pharmacological and phytochemical overview onSatureja

A review of medicinal plant of Middle East and North Africa (MENA) region as source in tuberculosis drug discovery

Preliminary antimycobacterial study on selected Turkish plants (Lamiaceae) against Mycobacterium tuberculosis and search for some phenolic constituents

Contact Info

Product

Resources

About