Effects of Solar Radiation on the Skin

Abstract

No one would underestimate the importance of sunlight to the evolution of life on the earth and its role in human development. However, all humans - especially individuals who are lightly pigmented or whose occupation or lifestyle exposes them to excessive amounts of sunlight - are potentially susceptible to its deleterious effects. These effects can range from acute biological responses, such as sunburn and skin tanning, to conditions resulting from chronic exposure such as photoaged skin and potentially life-threatening conditions such as skin cancer. The objective of this review is to present a concise and up-to-date perspective on the effects of UVB, UVA, visible, and infrared radiation on cutaneous biochemistry and physiology.

Dermatologic Signs and Symptoms of Substance Abuse

“…Ultraviolet (UV) radiation accounts for up to 90% of these cancers and is the only known modifiable risk factor associated with skin cancers [108][109][110]. While the importance of sun-protection is well recognized, excessive sunbathing and the overuse of tanning beds remains in our society.…”

“…Photoaging results in dry, leathery skin with deep wrinkles, blotchy pigmentation (resembling lentigines), and yellow hues known as solar elastosis. Telangiectasias and precancerous lesions, including actinic keratoses are also common [109,115]. In regards to the development of nonmelanoma skin cancer, a study conducted by Karagas et al showed that tanning bed users were 2.5 more likely to develop SCC and 1.5 times more likely to develop BCC [116].…”

Caracterização da pele fotoenvelhecida, desenvolvimento e eficácia clínica de formulações dermocosméticas por técnicas de biofísica e análise de imagem

“…No entanto, com os recentes progressos no campo da fototerapia, as evidências científicas atuais demonstram que estes comprimentos de onda também podem impactar as características cutâneas (POLEFKA et al, 2012).…”

Avaliação do potencial fotoquimioprotetor do extrato e das formulações tópicas contendo o extrato de Cecropia obtusa

“…Envelhecimento intrínseco, também conhecido como envelhecimento inato, é um processo natural que resulta da acumulação irreversível de mudanças degenerativas relacionadas com o envelhecimento biológico que ocorre com o passar dos anos (Polefka et al, 2012).…”

“…A exposição excessiva à luz solar é um fator de risco para o desenvolvimento de eritema, fotodermatoses, fotoenvelhecimento, imunossupressão e carcinogênese, devido à ação da radiação UVB e UVA (Polefka et al, 2012). O fotoenvelhecimento se sobrepõe ao processo de envelhecimento inato e é um grande perigo para a saúde, já que aumenta o risco de desenvolvimento de câncer de pele (Uitto, 2008).…”