Effects of sheep pineal fractions on the acitivity of male rat hypothalamiin vitro

Slama-Scemama, A.; L'Héritier, A.; Moszkowska, A; Horst, C. J. G. van der; Noteborn, H.P.J.M.; Moreé, A. de; Ebels, I.

doi:10.1007/bf01243428

Cited by 6 publications

(1 citation statement)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, Slama-Scemama et al (1979) showed that high molecular weight pineal substances, prepared under red light conditions, stimulate the gonadotropin releasing activity of the medial basal hypothalamus.…”

Section: Introductionmentioning

confidence: 99%

The effect of ovine pineal compounds prepared under red or green light on the activity of male rat anterior pituitariesin vitro

Slama-Scemama

Noteborn

Moreé

et al. 1985

J. Neural Transmission

Self Cite

View full text Add to dashboard Cite

A high molecular weight fraction XM100R (MW A 100,000) was prepared by ultrafiltration from ovine pineals using two different extraction methods under red light conditions (lambda greater than 600 nm). This fraction stimulates the release of radioimmunologically active luteinizing hormone (LH) of anterior pituitaries in vitro. The ultrafiltration fraction PM30R (MW greater than 30,000 and less than 100,000) was found to be radioimmunologically active only when the "Bensinger" extraction procedure was applied. However, when comparable fractions were prepared under green light and incubated with half-pituitaries, all the incubation media of the ultrafiltrated fractions, XM100R, PM30R, PM10R (MW greater than 10,000 and less than 30,000) UM2R (MW greater than 1000 and less than 10,000), UM05R (MW greater than 500 and less than 1000) and UM05F (MW greater than 500), reacted with anti-LH. This may mean that under green light conditions the high molecular weight ovine pineal compounds in XM100R are disintegrated and/or split up into small molecules which can stimulate the release of LH, or crossreact with the anti-LH serum.

show abstract

Section: Introductionmentioning

confidence: 99%

The effect of ovine pineal compounds prepared under red or green light on the activity of male rat anterior pituitariesin vitro

Slama-Scemama

Noteborn

Moreé

et al. 1985

J. Neural Transmission

Self Cite

View full text Add to dashboard Cite

show abstract

Presence of AVT-, ?-MSH-, LHRH- and somatostatin-like compounds in the rat pineal gland and their relationship with the UMO5R pineal fraction

et al. 1980

View full text Add to dashboard Cite

Comparison of some peptidic and proteic ovine pineal fractions with a bovine pineal E5 fraction

Noteborn

Ebels

Pévet

et al. 1982

J. Neural Transmission

View full text Add to dashboard Cite

Using rather simple and mild extraction and separation methods, three ovine pineal fractions (XM 300 R-PP7.2' and PP7.2 S) were obtained, which contain peptidic/proteic substances and which show fluorescence characteristics of indoles. The ovine fractions were compared with the bovine pineal E-5 fraction. The ovine fractions are chemically sensitive to normal laboratory light and stable in red light (lambda greater than 600 nm). Immunologically, these fractions and the bovine E 5 fraction are stable. From the results of radioimmunological experiments it was concluded that the bovine pineal E 5 fraction as well as the ovine pineal fraction XM 300 R-PP7.2 and PP7.2S may contain (a) peptide(s) ending by the same carboxy terminal tripeptide Pro-Arg-Gly(NH2).

show abstract

Effects of sheep pineal fractions on the acitivity of male rat hypothalamiin vitro

Cited by 6 publications

References 14 publications

The effect of ovine pineal compounds prepared under red or green light on the activity of male rat anterior pituitariesin vitro

The effect of ovine pineal compounds prepared under red or green light on the activity of male rat anterior pituitariesin vitro

Presence of AVT-, ?-MSH-, LHRH- and somatostatin-like compounds in the rat pineal gland and their relationship with the UMO5R pineal fraction

Comparison of some peptidic and proteic ovine pineal fractions with a bovine pineal E5 fraction

Contact Info

Product

Resources

About