2009
DOI: 10.1007/s12011-009-8372-3
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Effects of Selenium and L-Carnitine on Oxidative Stress in Blood of Rat Induced by 2.45-GHz Radiation from Wireless Devices

Abstract: The levels of blood lipid peroxidation, glutathione peroxidase, reduced glutathione, and vitamin C were used to follow the level of oxidative damage caused by 2.45 GHz electromagnetic radiation in rats. The possible protective effects of selenium and L-carnitine were also tested and compared to untreated controls. Thirty male Wistar Albino rats were equally divided into five groups, namely Groups A1 and A2: controls and sham controls, respectively; Group B: EMR; Group C: EMR + selenium, Group D: EMR + L-carnit… Show more

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Cited by 38 publications
(28 citation statements)
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References 35 publications
(40 reference statements)
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“…In addition, serum CAT activity was decreased (p<0.05) by administration of Se-vitamin E combination (Tables 2 and 3). These observations are in agreement with results of the investigations indicating the activity of CAT affected by acetic acid induced colitis [3,34]. CAT, an essential peroxisomal hydrogen peroxide-consuming enzyme, also decreased the oxidative effects of H 2 O 2 , superoxide dismutase, and GSH-Px that may play an important role as a system scavenging oxidative radicals.…”
Section: Discussionsupporting
confidence: 91%
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“…In addition, serum CAT activity was decreased (p<0.05) by administration of Se-vitamin E combination (Tables 2 and 3). These observations are in agreement with results of the investigations indicating the activity of CAT affected by acetic acid induced colitis [3,34]. CAT, an essential peroxisomal hydrogen peroxide-consuming enzyme, also decreased the oxidative effects of H 2 O 2 , superoxide dismutase, and GSH-Px that may play an important role as a system scavenging oxidative radicals.…”
Section: Discussionsupporting
confidence: 91%
“…ROS cause reversible or irreversible damage to biological molecules including DNA, lipids, proteins, carbohydrates, or any nearby molecule causing a cascade of chain reactions resulting in cellular damage [1,2,4,33]; hence, the biomolecules may lose their physiological functions in the tissues. Damage of these cellular components by free radicals may play an important role in various disorders of skin [8,9], colon [1-8, 10, 17], brain [33], and liver [15,16,34]. In Data are presented in mean±SD *p<0.05 (statistically significant compared to control group); **p<0.01 (statistically significant compared to control group); ***p<0.05 (statistically significant compared to acetic acid group); ****p<0.01 (statistically significant compared to acetic acid group) Data are presented in mean±SD *p<0.05 (statistically significant compared to control group); **p<0.01 (statistically significant compared to control group); ***p<0.05 (statistically significant compared to acetic acid group); ****p<0.01 (statistically significant compared to acetic acid group) this study, macroscopic and microscopic damages were significantly increased (p<0.01) by intrarectal injection of acetic acid and decreased (p<0.05 and p<0.01, respectively) in group treated by Se-vitamin E (Table 1).…”
Section: Discussionmentioning
confidence: 99%
“…The effect of LC on superoxide anion radical scavenging and hydrogen peroxide scavenging seems comparable with alpha-tocopherol and trolox (Gülçin, 2006). L-carnitine seems to have more protective effects than selenium on the electromagnetic radiation-induced blood toxicity by inhibiting free radical supporting antioxidant redox system (Gumral et al, 2009).…”
Section: Discussionmentioning
confidence: 82%
“…Erythrocyte reduced GSH activities while erythrocyte GSH-PX activities in EMR group were found to be lower than in EMR+L-carnitine group. The frequency of 2450 MHz induced blood toxicity by inhibiting free radicals supporting antioxidant redox system although selenium has no effect on the investigated values (43). Da Silva et al aimed to assess antioxidant effects of MLT on the sickle cell suspension.…”
Section: Tab 3 the Effects Of Melatonin And 2450 Mhz Emr On Malondimentioning
confidence: 99%