Effects of Salicylic Acid on the Metabolism of Mitochondrial Reactive Oxygen Species in Plants

Abstract

Different abiotic and biotic stresses lead to the production and accumulation of reactive oxygen species (ROS) in various cell organelles such as in mitochondria, resulting in oxidative stress, inducing defense responses or programmed cell death (PCD) in plants. In response to oxidative stress, cells activate various cytoprotective responses, enhancing the antioxidant system, increasing the activity of alternative oxidase and degrading the oxidized proteins. Oxidative stress responses are orchestrated by several phytohormones such as salicylic acid (SA). The biomolecule SA is a key regulator in mitochondria-mediated defense signaling and PCD, but the mode of its action is not known in full detail. In this review, the current knowledge on the multifaceted role of SA in mitochondrial ROS metabolism is summarized to gain a better understanding of SA-regulated processes at the subcellular level in plant defense responses.

Programmed Cell Death (PCD) in Plant: Molecular Mechanism, Regulation, and Cellular Dysfunction in Response to Development and Stress

“…- [97] Ethylene Ethylene-responsive element binding factors 2 (ERF2) in Petunia involved in PCD Petunia sp. [98] Ethylene-mediated ROS signaling plays a role in aerenchyma formation.…”

Effect of genotype, concentration and timing of salicylic acid application to Phalaenopsis against Dickeya dadantii infection

“…A lower SA concentration was observed to induce resistance in one rice variety, but a higher concentration was required in other varieties, indicating that different genotypes respond differently to specific SA concentrations. Klessig et al (2018) reported that SA regulates plant growth and development in a concentrationdependent manner, where a high level of SA stimulates ROS accumulation resulting in oxidative stress and cell death (Poór 2020). To find the best SA concentration for inducing resistance in very susceptible Phalaenopsis against SRD, we applied different SA concentrations to P. amabilis one day before D. dadantii inoculation.…”

Global view on the pathogenesis of benign thyroid disease based on historical, experimental, biochemical and genetic data, identifying the role of magnesium, selenium, coenzyme Q10 and iron in the context of the unfolded protein response and protein quality control of thyroglobulin

“…Modern studies have demonstrated that exogenous aspirin can activate the signaling pathways of the unfolded protein response [149] . Further information on aspirin and the endoplasmic reticulum can be found in publications dealing with plant physiology [150,151] . We can now say that the empiric use of aspirin to treat patients with thyroiditis as described in 1902 by de Quervain [12] was on the right track and simply ahead of its time.…”