Effects of resistance training on depression and cardiovascular disease risk in black men: Protocol for a randomized controlled trial

Busch, Andrew M.; Louie, Mark E.; SantaBarbara, Nicholas J.; Ajayi, Alex A.; Gleason, Neil; Dunsiger, Shira; Carey, Michael P.; Ciccolo, Joseph T.

doi:10.1016/j.mhpa.2019.100299

Cited by 1 publication

(6 citation statements)

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“…The full study protocol for this study has been previously described [ 21 ]. This study tested the effects of RT on interviewer-assessed depressive symptoms using a parallel group, single blind (i.e., assessors blind to condition) design.…”

Section: Methodsmentioning

confidence: 99%

“…A sample size of 50 was required for 80% power to detect between-group differences in depressive symptoms from baseline to end-of-treatment. Assumptions for this power calculation can be found in the protocol paper [ 21 ]. Design and reporting comply with the requirements of the Consolidated Standards of Reporting Trials (CONSORT) guidelines.…”

Section: Methodsmentioning

confidence: 99%

“…The components of each study arm were detailed previously [ 21 ]. A summary of treatment components is provided below.…”

Section: Methodsmentioning

confidence: 99%

“…The RT intervention has been described previously [ 21 ]. It was based on prior research on resistance exercise for depressive symptoms [ 13 ], while also adhering to the American College of Sports Medicine’s guidelines for developing and maintaining muscular fitness [ 32 ].…”

Section: Methodsmentioning

confidence: 99%

“…Given these considerations, and other research suggesting that RT may be an exercise modality particularly acceptable to Black men [ 20 ], the goal of this study was to investigate the effects of RT on depressive symptoms and explore its potential as a treatment option for community-dwelling Black men with depressive symptoms. The specific details of the study rationale and design for this pilot study have been reported previously [ 21 ]. Feasibility data, primary outcome (interviewer rated Quick Inventory of Depressive Symptomatology score), and secondary psychosocial outcomes are reported herein.…”

Section: Introductionmentioning

confidence: 99%

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Resistance training for Black men with depressive symptoms: a pilot randomized controlled trial to assess acceptability, feasibility, and preliminary efficacy

et al. 2022

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Background Depression is under-recognized in Black men, who are less likely to seek or have access to psychiatric treatment. Resistance training (RT; i.e., weight lifting) can improve depressive symptoms and may be more acceptable to Black men, but its effects have not been examined for Black men with depressive symptoms. Methods Fifty Black men with depressive symptoms were randomized to either (a) 12 weeks of RT (coupled with Behavioral Activation techniques to promote adherence) or (b) an attention-control group (Health, Wellness, and Education; HWE). Both groups met twice/week for 12 weeks, and follow-up assessments were done at end-of-treatment (EOT) and 6 months after enrollment. Changes in physical activity and muscular strength were collected as a manipulation check. The primary outcome was interviewer assessed symptoms of depression using the Quick Inventory of Depression Symptomology (QIDS). Secondary outcomes included self-reported depressive symptoms, anxiety, and stress. The association between change in QIDS from baseline to EOT and concurrent changes in physical activity and muscular strength in the RT group were explored as an initial assessment of mechanism. Longitudinal mixed effects regression models with subject-specific intercepts were used to examine intervention effects. Results A sample with high rates of medical comorbidities (e.g., 44% HIV positive), substance use (e.g., 34% smoking), and negative social determinates of health (e.g., 50% unemployed) was enrolled. Recruitment, engagement, and retention data indicate that the intervention and design were feasible. The RT group showed greater gains in self-reported exercise (b = 270.94, SE = 105.69, p = .01) and muscular strength (b = 11.71, SE = 4.23, p = .01 for upper body and b = 4.24, SE = 2.02, p = .04 for lower body) than the HWE group. The RT group had greater reductions in QIDS scores at both EOT (b = -3.00, SE = 1.34, p = .01) and 6 months (b = -2.63, SE = 1.81, p = .04). The RT group showed a greater reduction in anxiety at EOT (b = -2.67, SE = 1.06, p = .02). Findings regarding self-reported depressive symptoms and stress were non-significant, but in the expected direction with effect sizes in the small to medium range. In the RT group, improvement on the QIDS between baseline and EOT was associated with concurrent improvements in physical activity (b = 21.03, SE = 11.16, p = .02) and muscular strength (b = 1.27, SE = .44, p = .03 for upper body and b = .75, SE = .14, p = .03 for lower body). Conclusions Results suggest that RT is feasible and may be efficacious for reducing depressive symptoms among underserved urban Black men. Trial Registration ClinicalTrial.gov #: NCT03107039 (Registered 11/04/2017).

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

“…The components of each study arm were detailed previously [ 21 ]. A summary of treatment components is provided below.…”

Section: Methodsmentioning

confidence: 99%