Effects of repetitive transcranial magnetic stimulation on patients with mild cognitive impairment

Abstract

Mild cognitive impairment (MCI) is an intermediate state between normal aging and dementia, and there is no high-quality evidence that supports the pharmacologic treatment of MCI. Repetitive transcranial magnetic stimulation (rTMS) can improve the whole brain function by eliciting changes in synaptic plasticity. In this systematic review, the effectiveness and neural mechanisms of rTMS enhance MCI patients were analyzed. Future studies should optimize the localization for TMS, extend the period of the intervention effect evaluation, and explore how rTMS works in the treatment of MCI combining with neuroimaging technologies.