Effects of Pulsed Ultrasound Therapy on Sensory Nerve Conduction Parameters and the Pain Threshold Perceptions in Humans

Schuhfried, Othmar; Vukanovic, Damir; Kollmann, Christian; Pieber, Karin; Paternostro-Sluga, Tatjana

doi:10.1016/j.pmrj.2016.11.009

Cited by 5 publications

(3 citation statements)

References 20 publications

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“…[ 30 ] At this point, as it has been shown in many studies, low-intensity pulsed US application, which is accepted to have an intensity below 1 W/cm 2 due to underwater application, may have caused a positive change in electrophysiologic studies by having anti-inflammatory and regenerative effects on the stimulation of the median nerve conduction. [ 6 , 31 , 32 ]…”

Section: Discussionmentioning

confidence: 99%

Efficiency of therapeutic underwater ultrasound therapy in mild-to-moderate carpal tunnel syndrome: A randomized sham-controlled study

Bagcaci¹

2023

Turk J Phys Med Rehab

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Objectives: This study aimed to evaluate the efficiency of therapeutic pulsed ultrasound (US) applied underwater in mild-to-moderate carpal tunnel syndrome (CTS). Patients and methods: This randomized, placebo-controlled study included 75 patients (114 hands; 7 males, 68 females; mean age: 46.7±9.9 years; range, 24 to 64 years) diagnosed with CTS through clinical evaluation and electroneuromyography (ENMG) results between March 2012 and January 2013. Patients were randomized into three groups. Group 1 received underwater pulsed US, Group 2 received sham US, and Group 3 was the control group. All groups were given night splints. Patients were evaluated at baseline, at the end of treatment (two weeks), and 12 weeks after the treatment using clinical examination tests (Tinel, Phalen, and hand elevation test), hand grip strength, Visual Analog Scale (VAS) for pain, Pain Quality Assessment Scale (PQAS), and ENMG. Results: In all groups, a significant improvement was detected in the clinical assessment parameters, including the pain VAS, PQAS scores, physical examination outcomes, and hand grip strength. The decrease in VAS score and PQAS was found to be superior in the pulsed US group at both two weeks after the treatment and at the 12th week after the treatment compared to the sham US and control groups (p<0.001). Improvement in ENMG parameters, such as median motor latency, median sensorial velocity, and median sensory latency, was observed only in the underwater pulsed US group (p<0.001). Conclusion: Therapeutic underwater pulsed US is an effective, safe, and easy-to-apply treatment option in the conservative treatment of mild-to-moderate CTS.

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Section: Discussionmentioning

confidence: 99%

Efficiency of therapeutic underwater ultrasound therapy in mild-to-moderate carpal tunnel syndrome: A randomized sham-controlled study

Bagcaci¹

2023

Turk J Phys Med Rehab

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“…However, no additional placebo-controlled studies have emerged to support the independent use of ultrasound, with certain studies calling its utility into question [51][52][53]. A Cochrane review by Page and colleagues concluded that there is only poor evidence based on limited data to suggest that therapeutic ultrasound is more effective than placebo for treatment of CTS [54].…”

Section: Ultrasoundmentioning

confidence: 99%

Non-operative Treatment of Carpal Tunnel Syndrome

Ostergaard

Meyer

Earp

2020

Curr Rev Musculoskelet Med

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Purpose of Review To determine the current evidence for various non-operative therapies in the treatment of carpal tunnel syndrome Recent Findings Multiple non-operative treatment modalities exist in the treatment of mild to moderate carpal tunnel syndrome. While certain modalities such as splinting and corticosteroid injections have moderate-to high-quality evidence to support use, other less commonly used treatments have fewer therapeutic indications in the current literature. Summary Healthcare providers should be able to initiate the appropriate diagnostic evaluation and assess the utility of nonoperative therapies in the treatment of carpal tunnel syndrome. Moreover, healthcare providers should also be able to understand the evidence behind each treatment and the indications for surgical intervention.

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“…In the intensity range of 0.5–2.0 W/cm 2 , therapeutic US may have the potential to induce a variety of biophysical effects in tissues. 19 Therapeutic US experiments on stimulation of nerve conduction and regeneration, 20 21 and discoveries of its anti-inflammatory effects 22 all support that therapeutic US may promote recovery of nerve compression. An RCT published in BMJ showed more pronounced subjective symptoms and electroneurographic variables for therapeutic US than sham control in patients with mild to moderate CTS.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of therapeutic ultrasound for the treatment of carpal tunnel syndrome (the USTINCTS trial): study protocol for a three-arm, prospective, multicentre, randomised controlled trial

et al. 2022

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IntroductionThere has no consensus on optimal management of carpal tunnel syndrome (CTS), the most common compression neuropathy. Conservative therapy is generally accepted as first-line intervention. Therapeutic ultrasound has been widely reported to be treatment beneficial in nerve regeneration and conduction, and further accelerate compression recovery. The purpose of this study is to investigate the effectiveness of therapeutic ultrasound for CTS treatment.Methods and analysisThis study protocol entails a three-arm, prospective, multicentre, randomised controlled trial. 162 eligible adult participants diagnosed with mild to moderate CTS by using criteria developed from a consensus survey by the UK Primary Care Rheumatology Society will be assigned to either (1) therapeutic ultrasound, (2) night splint or (3) therapeutic ultrasound +night splint (combined) group. Primary outcome will be difference in Symptom Severity Scale of Boston Carpal Tunnel Questionnaire (BCTQ-SSS) at 6-week between night splint and therapeutic ultrasound +night splint groups. Secondary outcomes include Functional Status Scale of BCTQ, sleep questionnaire for interrupted sleep, EuroQol-5D for general health, Hospital Anxiety and Depression Scale for mental status, Work Limitations Questionnaire-25 for functional limitations at work, Global Rating of Change for treatment success and recurrence rate, physical examination, electrophysiological and ultrasound parameters. Intention-to-treat analyses will be used.Ethics and disseminationEthics committees of all clinical centres have approved this study. The leading centre is Shanghai Sixth People’s Hospital, whose approval number is 2021-152. New versions with appropriate amendments will be submitted to the committee for further approval. Final results will be published in peer-reviewed journals and presented at local, national and international conferences.Trial registration numberChiCTR2100050701.

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Effects of Pulsed Ultrasound Therapy on Sensory Nerve Conduction Parameters and the Pain Threshold Perceptions in Humans

Abstract: I.

Cited by 5 publications

References 20 publications

Efficiency of therapeutic underwater ultrasound therapy in mild-to-moderate carpal tunnel syndrome: A randomized sham-controlled study

Efficiency of therapeutic underwater ultrasound therapy in mild-to-moderate carpal tunnel syndrome: A randomized sham-controlled study

Non-operative Treatment of Carpal Tunnel Syndrome

Effectiveness of therapeutic ultrasound for the treatment of carpal tunnel syndrome (the USTINCTS trial): study protocol for a three-arm, prospective, multicentre, randomised controlled trial

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