Effects of pudendal nerve injury in the female rat

Comparison of leak point pressure methods in an animal model of stress urinary incontinence

“…Early studies observed changes in voiding behavior following pudendal nerve injury and bladder and urethral changes following delivery [4,5], while others used cystometry to evaluate bladder and urethral changes following delivery [6]. Some used sneeze induction as a way to measure the continence mechanism in rats [7,8].…”

Long-Term Effects on Pressure and Electromyography in a Rat Model of Anal Sphincter Injury

“…Animal models have been used to study the urological effects of pudendal nerve crush. 13,14 Likewise, animal models have been used to demonstrate anal pathophysiology. [13][14][15] However, there is no good animal model that has compared the effects of pudendal nerve and direct sphincter injury on in vivo anal sphincter function.…”

“…13,14 Likewise, animal models have been used to demonstrate anal pathophysiology. [13][14][15] However, there is no good animal model that has compared the effects of pudendal nerve and direct sphincter injury on in vivo anal sphincter function. The goal of this study was to use our previous methods of measuring anal sphincter pressure and EMG, 15 to study the chronic effects of anal sphincter and pudendal nerve injury on anal sphincter function.…”

Experimental Models of Neuropathic Fecal Incontinence: An Animal Model of Childbirth Injury to the Pudendal Nerve and External Anal Sphincter

“…Existing animal models of pudendal nerve injury have been used to study the pathogenesis of genuine stress urinary incontinence and the effects of childbirth on the external urethral sphincter. [12][13][14] An animal model of pudendal nerve transection was developed by Congilosi et al in a study of skeletal muscle neosphincter construction. 15 An experimental animal model that simulates childbirth injury to the pudendal nerve and the consequent effects on external anal sphincter (EAS) structure and function would facilitate investigation of the pathophysiology of neuropathic fecal incontinence and provide an experimental platform for study of techniques to ameliorate nerve injury and promote recovery of EAS function.…”