Effects of probiotics on body weight, body mass index, fat mass and fat percentage in subjects with overweight or obesity: a systematic review and meta‐analysis of randomized controlled trials

Abstract

SummaryA systematic review and meta-analysis of randomized controlled trials was conducted to examine the effects of probiotic supplementation on body weight, body mass index (BMI), fat mass and fat percentage in subjects with overweight (BMI 25-29.9 kg m À2 ) or obesity (BMI ≥30 kg m À2). MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials were searched for studies published between 1946 and September 2016. A meta-analysis, using a random effects model, was performed to calculate the weighted mean difference between the intervention and control groups. Of 800 studies identified through the literature search, 15 were finally included. The studies comprised a total of 957 subjects (63% women), with the mean BMI being 27.6 kg m À2 and the duration of the interventions ranging

Possible Kefir Biological Effects: 4: Effect of Kefir Beverage on The Histopathological and Macroscopical Changes in Adipose Tissue of High Fat-Fed STZ- Induced Diabetic Male Wistar Rat

“…Regarding the morphology of the adipose tissue, absolute weight was determined and mean relative weight was calculated; represented data indicated nonsignificance between the different groups; and that was expected cause of kefir beverage feeding had no effects in increasing fat mass formed, also there were no histopathological changes between the normal animals and diabetic ones.The number of studies included in the metaanalyses of the effects of probiotics on body fat mass and the percentage was low, thus meaning that the latter results should be interpreted with caution.The agreements go with the overall of the seven studies reporting changes in fat mass showed a larger reduction in body fat mass and fat percentage in the intervention groups compared with the control groups, but the difference was non-significant because effect sizes were small (Borgeraas et al, 2018).…”

“…et al, (2007) explained that the bodyweight of the diabetic rats which induced experimentally by streptozotocin decreased comparing with the normal rats. Yasamin et al, (2016) observed in their study that Kefir drink leads to a similar weight loss, compared with milk in overweight or obese premenopausal women.A total of 13 studies revealed the effects of probiotic supplementation consumption and found that the administration of probiotics was associated with a significantly larger reduction in BMI and weight loss (Borgeraas et al, 2018). Zemel et al, (2004) hypothesized that a dairy-rich diet containing kefir drink would lead to a greater weight loss, as kefir drink might have the antiobesity properties of dairy products and probiotics in combination.…”

Nonalcoholic Fatty Liver Disease: A Challenge from Mechanisms to Therapy

“…Interestingly, administration of probiotics resulted in a significantly larger reduction in body weight expressed as BMI compared to placebo; however, the effect was small. In contrast, the effect of probiotics on fat mass was non-significant [54]. With obesity being the main driver of NAFLD, it is interesting to evaluate the effects of the induced gut flora modification in obese patients.…”

Effect of peeling and unpeeling on yield, chemical structure, morphology and pasting properties of starch extracted from three diverse potato cultivars of Pakistan

“…Each treatment was performed in triplicates in order to calculate mean and standard deviation. The control randomised design (CRD) for the randomisation of eighteen experimental units (total six treatments with triplicates of each) was designed by using table of randomisation (Borgeraas et al ., ).…”