Effects of Pleurotus ostreatus on Blood Pressure and Glycemic Status of Hypertensive Diabetic Male Volunteers

Abstract

Different species of mushrooms are being used increasingly for their nutritional and medicinal values. They are used in traditional medical practice in the treatment and prevention of diabetes, obesity, heart diesaes, hyperacidity, cancer and hypertension. This study was designed to see the effects of Pleurotus ostreatus on blood pressure and glycemic status of hypertensive diabetic male volunteers. The study was carried out in the National Mushroom development and Extension Center (NAMDEC) laboratory, Savar, Dhaka in collaboration with the Department of Pharmacy along with the Department of Biochemistry and Molecular Biology, Jahangirnagar University. A total of 27 hypertensive male volunteers suffering from type 2 diabetes mellitus with age range of 32 to 68 years, who were free from renal impairment and other known acute or chronic diseases were included in the study. Blood pressure, fasting plasma glucose, HbA1c and serum creatinine were measured before and after 3 months of regular intake of 3 grams mushroom powder capsule daily in in 3 divided doses. However they were allowed to continue the drugs they were taking already. The study showed that after 3 months of regular intake of Pleurotus ostreatus mushroom, both systolic and diastolic blood pressure decreased significantly (p<0.001). It was also observed that, Pleurotus ostreatus decreased fasting plasma glucose level significantly (p<0.001). Reduction of HbA1c % observed after 3 months of mushroom intake was found to be significant (p<0.001). But there was no significant change of plasma creatinine level (p>0.05) indicating Pleurotus ostreatus has no detrimental effect on renal system. From the study, it can be said that, Pleurotus ostreatus mushroom intake improves glycemic status and blood pressure control in diabetic hypertensive subjects. DOI: http://dx.doi.org/10.3329/bjmb.v6i1.13280 Bangladesh J Med Biochem 2013; 6(1): 5-10

Circular reuse of bio-resources: the role ofPleurotusspp. in the development of functional foods

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Effect of Pleurotus ostreatus powder addition in vegetable soup on ß‐glucan content, sensory perception, and acceptability

“…Daily doses of 3-5 g of P. ostreatus powder were found to decrease fasting plasma glucose level in both healthy people and type-2 diabetic patients (Agrawal et al, 2010;Choudhury et al, 2013). powder on both healthy and unhealthy humans.…”

“…powder on both healthy and unhealthy humans. Daily doses of 3-5 g of P. ostreatus powder were found to decrease fasting plasma glucose level in both healthy people and type-2 diabetic patients (Agrawal et al, 2010;Choudhury et al, 2013). Slightly higher daily doses, in the range 5-10 g, were found to enhance the innate and acquired immune responses in healthy human subjects (Sun et al, 2014).…”

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