Effects of Periosteum Wrapped Around Tendon in a Bone Tunnel: A Biomechanical and Histological Study in Rabbits

Ohtera, Kozo; Yamada, Yasuharu; Aoki, Mitsuhiro; Sasaki, Terukatsu; Yamakoshi, Ken-ichi

doi:10.1615/critrevbiomedeng.v28.i12.190

Cited by 35 publications

(24 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The observation results were collected with experimental results for a rabbit ACL reconstruction model using periosteum wrapped around tendon in a bone tunnel. 6,27 Therefore, the presence of fibrocartilage tissue in this study likely strengthened the attachment at the tendon-bone interface. Biomechanical testing demonstrated a progressive increase in tendon pullout strength that followed bone ingrowth, mineralization, and incorporation of the healing tissue.…”

Section: Discussionmentioning

confidence: 69%

Photoencapsulation of Bone Morphogenetic Protein-2 and Periosteal Progenitor Cells Improve Tendon Graft Healing in a Bone Tunnel

et al. 2008

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 69%

Photoencapsulation of Bone Morphogenetic Protein-2 and Periosteal Progenitor Cells Improve Tendon Graft Healing in a Bone Tunnel

et al. 2008

View full text Add to dashboard Cite

show abstract

“…This resulted in direct bonding between the implanted graft and the surrounding bone after three weeks. Other approaches to improve bone tunnel osteointegration include the addition of periosteum wraps to the region of the graft that interacts with bone (119–123) and of growth factors such as BMP-2 (85, 124–127), BMP-7 (128), and granulocyte colony stimulating factor (129). Additionally, the direct application of MSCs for improving graft-to-bone integration has been explored (130–132).…”

Section: Current Approaches To Interface Regenerationmentioning

confidence: 99%

Functional Attachment of Soft Tissues to Bone: Development, Healing, and Tissue Engineering

Thomopoulos

2013

Annu. Rev. Biomed. Eng.

366

404

View full text Add to dashboard Cite

Connective tissues such as tendons or ligaments attach to bone across a multitissue interface with spatial gradients in composition, structure, and mechanical properties. These gradients minimize stress concentrations and mediate load transfer between the soft and hard tissues. Given the high incidence of tendon and ligament injuries and the lack of integrative solutions for their repair, interface regeneration remains a significant clinical challenge. This review begins with a description of the developmental processes and the resultant structure-function relationships that translate into the functional grading necessary for stress transfer between soft tissue and bone. It then discusses the interface healing response, with a focus on the influence of mechanical loading and the role of cell-cell interactions. The review continues with a description of current efforts in interface tissue engineering, highlighting key strategies for the regeneration of the soft tissue–to-bone interface, and concludes with a summary of challenges and future directions.

show abstract

“…The implantation of periosteal autograft [103-106], photo-encapsulated rhBMP-2 and periosteal progenitor cells [107], autologous mesenchymal stem cells (MSC) [53,108,109] and synovial MSC [110] and bone marrow aspirates [106] have been reported to accelerate early tendon graft-bone tunnel healing.…”

Section: Recent Development In the Improvement Of Tbi Healingmentioning

confidence: 99%

Biology and augmentation of tendon-bone insertion repair

et al. 2010

View full text Add to dashboard Cite

Surgical reattachment of tendon and bone such as in rotator cuff repair, patellar-patella tendon repair and anterior cruciate ligament (ACL) reconstruction often fails due to the failure of regeneration of the specialized tissue ("enthesis") which connects tendon to bone. Tendon-to-bone healing taking place between inhomogenous tissues is a slow process compared to healing within homogenous tissue, such as tendon to tendon or bone to bone healing. Therefore special attention must be paid to augment tendon to bone insertion (TBI) healing. Apart from surgical fixation, biological and biophysical interventions have been studied aiming at regeneration of TBI healing complex, especially the regeneration of interpositioned fibrocartilage and new bone at the healing junction. This paper described the biology and the factors influencing TBI healing using patella-patellar tendon (PPT) healing and tendon graft to bone tunnel healing in ACL reconstruction as examples. Recent development in the improvement of TBI healing and directions for future studies were also reviewed and discussed.

show abstract

Effects of Periosteum Wrapped Around Tendon in a Bone Tunnel: A Biomechanical and Histological Study in Rabbits

Cited by 35 publications

References 0 publications

Photoencapsulation of Bone Morphogenetic Protein-2 and Periosteal Progenitor Cells Improve Tendon Graft Healing in a Bone Tunnel

Photoencapsulation of Bone Morphogenetic Protein-2 and Periosteal Progenitor Cells Improve Tendon Graft Healing in a Bone Tunnel

Functional Attachment of Soft Tissues to Bone: Development, Healing, and Tissue Engineering

Biology and augmentation of tendon-bone insertion repair

Contact Info

Product

Resources

About