Effects of Paenibacillus nematophilus on the entomopathogenic nematode Heterorhabditis megidis

Enright, Michael R.; Griffin, Christine T.

doi:10.1016/j.jip.2004.10.002

Cited by 35 publications

(14 citation statements)

References 26 publications

(31 reference statements)

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“…For example, while low levels of fusaric acid, a toxin produced by the fungus Fusarium oxysporum , increase production of the antifungal enzyme β-1,3-glucanase by P. polymyxa strains WR-2 and SQR-21, higher levels of fusaric acid actually decrease their production and result in reduced P. polymyxa growth [61]. Furthermore, Paenibacillus may compete with other beneficial organisms [62, 63]. …”

Section: Biocontrolmentioning

confidence: 99%

Current knowledge and perspectives of Paenibacillus: a review

et al. 2016

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Isolated from a wide range of sources, the genus Paenibacillus comprises bacterial species relevant to humans, animals, plants, and the environment. Many Paenibacillus species can promote crop growth directly via biological nitrogen fixation, phosphate solubilization, production of the phytohormone indole-3-acetic acid (IAA), and release of siderophores that enable iron acquisition. They can also offer protection against insect herbivores and phytopathogens, including bacteria, fungi, nematodes, and viruses. This is accomplished by the production of a variety of antimicrobials and insecticides, and by triggering a hypersensitive defensive response of the plant, known as induced systemic resistance (ISR). Paenibacillus-derived antimicrobials also have applications in medicine, including polymyxins and fusaricidins, which are nonribosomal lipopeptides first isolated from strains of Paenibacillus polymyxa. Other useful molecules include exo-polysaccharides (EPS) and enzymes such as amylases, cellulases, hemicellulases, lipases, pectinases, oxygenases, dehydrogenases, lignin-modifying enzymes, and mutanases, which may have applications for detergents, food and feed, textiles, paper, biofuel, and healthcare. On the negative side, Paenibacillus larvae is the causative agent of American Foulbrood, a lethal disease of honeybees, while a variety of species are opportunistic infectors of humans, and others cause spoilage of pasteurized dairy products. This broad review summarizes the major positive and negative impacts of Paenibacillus: its realised and prospective contributions to agriculture, medicine, process manufacturing, and bioremediation, as well as its impacts due to pathogenicity and food spoilage. This review also includes detailed information in Additional files 1, 2, 3 for major known Paenibacillus species with their locations of isolation, genome sequencing projects, patents, and industrially significant compounds and enzymes. Paenibacillus will, over time, play increasingly important roles in sustainable agriculture and industrial biotechnology.Electronic supplementary materialThe online version of this article (doi:10.1186/s12934-016-0603-7) contains supplementary material, which is available to authorized users.

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Section: Biocontrolmentioning

confidence: 99%

Current knowledge and perspectives of Paenibacillus: a review

et al. 2016

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“…Concomitant infection by EPNs and Paenibacillus spp. had little measurable effects on nematode reproduction or energy reserves but spore-encumbered IJs were less motile and infected fewer insects (El-Borai et al, 2005;Enright and Griffin, 2005) compared to spore-free IJs. The degree to which Paenibacillus spp.…”

Section: Introductionmentioning

confidence: 99%

Entomopathogenic nematodes, phoretic Paenibacillus spp., and the use of real time quantitative PCR to explore soil food webs in Florida citrus groves

Campos‐Herrera

El-Borai

Stuart

et al. 2011

Journal of Invertebrate Pathology

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“…Tc orthologues have since been found in other Gramnegative bacteria including Serratia entomophila and X. nematophilus (Hurst et al, 2000;Sergeant et al, 2003) and have also been found in the Gram-positive bacterium Paenibacillus (Enright & Griffin, 2005). This implies that the Tc's may be important in insect pathogens.…”

Section: Introductionmentioning

confidence: 99%

The Yersinia pseudotuberculosis and Yersinia pestis toxin complex is active against cultured mammalian cells

et al. 2008

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The toxin complex (Tc) genes were first identified in the insect pathogen Photorhabdus luminescens and encode~1 MDa protein complexes which are toxic to insect pests. Subsequent genome sequencing projects have revealed the presence of tc orthologues in a range of bacterial pathogens known to be associated with insects. Interestingly, members of the mammalianpathogenic yersiniae have also been shown to encode Tc orthologues. Studies in Yersinia enterocolitica have shown that divergent tc loci either encode insect-active toxins or play a role in colonization of the gut in gastroenteritis models of rats. So far little is known about the activity of the Tc proteins in the other mammalian-pathogenic yersiniae. Here we present work to suggest that Tc proteins in Yersinia pseudotuberculosis and Yersinia pestis are not insecticidal toxins but have evolved for mammalian pathogenicity. We show that Tc is secreted by Y. pseudotuberculosis strain IP32953 during growth in media at 28 6C and 37 6C. We also demonstrate that oral toxicity of strain IP32953 to Manduca sexta larvae is not due to Tc expression and that lysates of Escherichia coli BL21 expressing the Yersinia Tc proteins are not toxic to Sf9 insect cells but are toxic to cultured mammalian cell lines. Cell lysates of E. coli BL21 expressing the Y. pseudotuberculosis Tc proteins caused actin ruffles, vacuoles and multinucleation in cultured human gut cells (Caco-2); similar morphology was observed after application of a lysate of E. coli BL21 expressing the Y. pestis Tc proteins to mouse fibroblast NIH3T3 cells, but not Caco-2 cells. Finally, transient expression of the individual Tc proteins in Caco-2 and NIH3T3 cell lines reproduced the actin and nuclear rearrangement observed with the topical applications. Together these results add weight to the growing hypothesis that the Tc proteins in Y. pseudotuberculosis and Y. pestis have been adapted for mammalian pathogenicity. We further conclude that Tc proteins from Y. pseudotuberculosis and Y. pestis display differential mammalian cell specificity in their toxicity.

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Effects of Paenibacillus nematophilus on the entomopathogenic nematode Heterorhabditis megidis

Cited by 35 publications

References 26 publications

Current knowledge and perspectives of Paenibacillus: a review

Current knowledge and perspectives of Paenibacillus: a review

Entomopathogenic nematodes, phoretic Paenibacillus spp., and the use of real time quantitative PCR to explore soil food webs in Florida citrus groves

The Yersinia pseudotuberculosis and Yersinia pestis toxin complex is active against cultured mammalian cells

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