Effects of organic modifiers on the size-controlled synthesis of hydroxyapatite nanorods

Organic/Inorganic bioactive materials Part III: in vitro bioactivity of gelatin/silicocarnotite hybrids

“…Nanostructured HA offers a favourable environment for osteoconduction, protein adhesion and bone regrowth [5,6]. Much of the research interests today focus on the fabrication of artificial bone like ceramic/ polymer composites [6][7][8][9] especially on HA/gelatin nanocomposites [1,[10][11][12][13][14][15][16][17][18][19][20][21][22], fluorapatite (FHA)/ gelatin nanocomposites [23], carbonated fluorapatite (CO 3 FHA)/gelatin nanocomposites [24]; drug delivery carrier [25,26] and protein separation [27].…”

Synthesis and characterization of bioactive hydroxyapatite–calcite nanocomposite for biomedical applications

“…Citrate is contained in fresh wet bone by about 1 wt.% and is believed to take part in the formation and/or dissolution of bone apatite [15]. Citric acid and citrate has been used by several researchers during HA synthesis with different objectives [12][13][14][15][16][17]. Rhee et al has reported that the carboxylic groups present in citric acid have induced apatite formation on the collagen membrane [15].…”

“…Organic modifiers such as ethylene glycol, trisodium citrate, citric acid, polyethylene glycol, Tween20, D-sorbitol, citric acid, sodium dodecyl sulphate, sodium dodecylbenzene sulphonate and polyoxyethylene are widely used in the morphology and size controlled synthesis of nanocrystalline HA [12][13][14]. Citrate is contained in fresh wet bone by about 1 wt.% and is believed to take part in the formation and/or dissolution of bone apatite [15].…”

Effects of hydrothermal temperature and time on hydrothermal synthesis of colloidal hydroxyapatite nanorods in the presence of sodium citrate

“…The obtained particles are needle-like with mean lengths ranging from 20-100 nm. Wang and her coworkers [35,36] However, for all the references before, including our previous works, the focus was restricted to one aspect alone, such as the influence of hydrothermal temperature on particle morphology, the influence of hydrothermal time on colloidal stability.…”