Effects of orally administered immunostimulants on inflammatory gene expression and sea lice (Lepeophtheirus salmonis) burdens on Atlantic salmon (Salmo salar)

Covello, J; Friend, Sarah; Purcell, Sara L.; Burka, John F.; Markham, Robert; Donkin, Alan W; Groman, David B.; Fast, Mark D.

doi:10.1016/j.aquaculture.2012.08.051

Cited by 43 publications

(68 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…No obstante, en un estudio con salmón del Atlántico, el grupo alimentado con β-glucano presentó 24% más de infestación que el grupo control, posible-mente debido a una dosis posiblemente inapropiada (Covello et al, 2012). Por otro lado, el aceite esencial de orégano como suplemento dietético, aumenta la protección contra las infecciones mixtas de parásitos (piojos, copépodos) y bacterias del género Vibrio (Yiagnisis et al, 2009).…”

Section: Lepeophtheirus Salmonisunclassified

Aditivos Mucogénicos para el Control de Caligus rogercresseyi en Salmón del Atlántico (Salmo salar)

Concha

Olivares

Fonseca-Salamanca

et al. 2017

Rev. investig. vet. Perú

View full text Add to dashboard Cite

El mucus es uno de los componentes más importantes de la inmunidad del pescado, contiene componentes de la inmunidad innata como glicoproteínas, lisozima, proteínas del complemento, enzimas proteolíticas, péptidos antimicrobianos e inmunoglobulinas. Se revisa información actualizada concerniente a la generación, fisiología y efectos del mucus en el salmón del Atlántico, así como de posibles aditivos mucogénicos para el control de parásitos que puedan ser atractivos para ser utilizados a futuro en la disminución de Caligus rogercresseyi. En virtud del cometido se realizó una búsqueda de datos multidisciplinarios de texto completo. Los tópicos incluidos en el proceso de investigación corresponden al salmón, al mucus y a los aditivos mucogénicos. Se encontró que el aditivo que genera un mayor aumento de los componentes del mucus es el probiótico Bacillus sp. Los hallazgos sugieren que se necesita más investigación para desentrañar las implicaciones de la inmunidad de la mucosa de la piel sobre el bienestar de los peces y las enfermedades de importancia biológica.Palabras clave: mucus; salmón; aditivo mucus ABSTRACT Mucus is one of the most important components of fish immunity, it contains components of innate immunity such as glycoproteins, lysozyme, complement proteins, proteolytic enzymes, antimicrobial peptides and immunoglobulins. Current information

show abstract

Section: Lepeophtheirus Salmonisunclassified

Aditivos Mucogénicos para el Control de Caligus rogercresseyi en Salmón del Atlántico (Salmo salar)

Concha

Olivares

Fonseca-Salamanca

et al. 2017

Rev. investig. vet. Perú

View full text Add to dashboard Cite

show abstract

“…Salmon on the treated diet had reduced L. salmonis infection levels (∼40% lower than controls) and showed enhanced site-specific inflammation. The difference in infection levels between control and treated fish increased over time, suggesting that the response to the feed was maintained (Covello et al 2012). Purcell et al (2013) identified that a previous exposure to lice resulted in lower reinfection density than naïvely infected salmon, and that this effect was increased further through CpG-ODN immunostimulation.…”

Section: Introductionmentioning

confidence: 99%

“…Fish were infected following the method of Covello et al (2012). Following seawater acclimatization, treatment tanks (total = 9 tanks) were randomly assigned to one of three treatment groups and placed on one of the following three diets: control/base feed, LD, or HD.…”

Section: Lice Exposures and Samplingmentioning

confidence: 99%

“…Spleen, skin, and head kidney were excised from each salmon individual and frozen on dry ice. In an effort to standardize the sampling, skin samples were always taken posterior to the left pectoral fin above the lateral line (as in Covello et al 2012). All tissues were stored at −80°C until required for gene expression analysis.…”

Section: Lice Exposures and Samplingmentioning

confidence: 99%

“…Covello et al (2012) tested the effectiveness of incorporating CpG oligodeoxynucleotide (ODN) or yeast extracts into post-smolt Atlantic salmon (Salmo salar) feed. Salmon on the treated diet had reduced L. salmonis infection levels (∼40% lower than controls) and showed enhanced site-specific inflammation.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Host–parasite transcriptomics during immunostimulant-enhanced rejection of salmon lice (Lepeophtheirus salmonis) by Atlantic salmon (Salmo salar)

Sutherland

Covello

Friend

et al. 2017

FACETS

View full text Add to dashboard Cite

Salmon lice (Lepeophtheirus salmonis) are important ectoparasites of wild and farmed salmonids and cause major losses to the salmon farming industry throughout the Northern Hemisphere. With the emergence of resistance to several commonly used parasiticides, novel control strategies and integration of multiple treatment options are needed, including host immunostimulation. Here, we investigate the effects of a functional feed containing a peptidoglycan and nucleotide formulation on L. salmonis infection of Atlantic salmon (Salmo salar) by characterizing lice infection levels, the expression of several host immune genes, and the parasite transcriptomic response to the immunostimulated host. Although initial infection intensities were low, the low dose (LD) immunostimulant diet reduced the total lice burden by 50% relative to controls. Immunostimulant fed hosts upregulated interleukin-1β in the skin and spleen. This gene has been implicated in successful responses of several salmonid species to salmon lice but is typically not observed in Atlantic salmon, suggesting a favorable influence on the immune response. Lice infecting LD immunostimulated salmon overexpressed genes putatively involved in parasite immunity, including carboxylesterases, and underexpressed genes putatively involved in feeding (e.g., proteases). These lice response genes further improve the characterization of the transcriptome of the non-model parasite by identifying genes potentially involved in evading host immunity.

show abstract

Sea lice population and sex differences in P-glycoprotein expression and emamectin benzoate resistance on salmon farms in the Bay of Fundy, New Brunswick, Canada

2013

View full text Add to dashboard Cite

show abstract

Effects of orally administered immunostimulants on inflammatory gene expression and sea lice (Lepeophtheirus salmonis) burdens on Atlantic salmon (Salmo salar)

Cited by 43 publications

References 29 publications

Aditivos Mucogénicos para el Control de Caligus rogercresseyi en Salmón del Atlántico (Salmo salar)

Aditivos Mucogénicos para el Control de Caligus rogercresseyi en Salmón del Atlántico (Salmo salar)

Host–parasite transcriptomics during immunostimulant-enhanced rejection of salmon lice (Lepeophtheirus salmonis) by Atlantic salmon (Salmo salar)

Sea lice population and sex differences in P-glycoprotein expression and emamectin benzoate resistance on salmon farms in the Bay of Fundy, New Brunswick, Canada

Contact Info

Product

Resources

About