Effects of omega-3 fatty acids on coronary restenosis, intima–media thickness, and exercise tolerance: A systematic review

Balk, Ethan M; Lichtenstein, Alice H.; Chung, Mei; Kupelnick, Bruce; Chew, Priscilla; Lau, Joseph

doi:10.1016/j.atherosclerosis.2005.06.042

Cited by 56 publications

(34 citation statements)

References 37 publications

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“…Other systematic reviews focused on surrogate markers of CVD such as lipid profiles, the majority of which found a protective effect of n-3 PUFA on triglycerides and a neutral or small adverse effect on total cholesterol, low density lipoprotein cholesterol and high density lipoprotein cholesterol [33][34][35][36][37][38][39]. Moreover, there is little evidence on vegetable origin n-3 PUFA in relation to CVD.…”

Section: Clinical Use For Cardiovascular Disease Preventionmentioning

confidence: 99%

Prevention of Cardiovascular Disease by Dietary n-3 Fatty Acid

Raghu¹

2016

IJIMS

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Section: Clinical Use For Cardiovascular Disease Preventionmentioning

confidence: 99%

Prevention of Cardiovascular Disease by Dietary n-3 Fatty Acid

Raghu¹

2016

IJIMS

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“…Other systematic reviews focused on surrogate markers of cardiovascular disease such as lipid profiles, the majority of which found a protective effect of n-3 PUFA on triglycerides and a neutral or small adverse effect on total cholesterol, low density lipoprotein cholesterol, and high density lipoprotein cholesterol. [33][34][35][36][37][38][39] Moreover, there is little evidence on n-3 PUFA sourced from vegetables in relation to cardiovascular disease. Although a wide range of adult populations, predominantly from America and Europe, were considered in these reviews, it should be cautioned that some of the systematic reviews included subjects who had already experienced a cardiovascular disease event and were secondary prevention trials.…”

Section: Clinical Use For Cardiovascular Disease Preventionmentioning

confidence: 99%

Role of n-3 series polyunsaturated fatty acids in cardiovascular disease prevention

Lee¹,

Hiramatsu²

2011

NDS

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Cardiovascular disease is a major cause of morbidity and mortality worldwide. Its prevention through a healthy lifestyle and appropriate diet is important. Omega-3 polyunsaturated fatty acids (n-3 PUFA) therapy has shown promise in both primary and secondary prevention of cardiovascular disease. This commentary discusses the nutritional role of n-3 PUFA, including its metabolism and physiological role, comparison with n-6 series PUFA, as well as complications due to deficiency. Clinical use of n-3 PUFA for the prevention and treatment of cardiovascular disease, recommended intake, and potential adverse effects will also be examined. The available scientific evidence suggests that its supplementation and clinical use ranging from 0.4 to 1 g/day can provide tangible benefits. However, further studies are required to determine optimal dosing and the relative ratio of docosahexaenoic acid and eicosapentaenoic acid that provides maximal cardioprotection and treatment of cardiovascular disease.

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“…Three meta-analyses performed to examine these studies concluded that fish oils do prevent restenosis. [14][15][16] However, the most recently published meta-analysis was only able to document clinically important benefits in 5 of 12 studies. 15 A 13th study was excluded due to high fish oil intake.…”

Section: Fish Oils In Disease Preventionmentioning

confidence: 99%

“…[14][15][16] However, the most recently published meta-analysis was only able to document clinically important benefits in 5 of 12 studies. 15 A 13th study was excluded due to high fish oil intake. 17 Interest then shifted to studies of secondary prevention.…”

Section: Fish Oils In Disease Preventionmentioning

confidence: 99%

Are dietary recommendations for the use of fish oils sustainable?

Jenkins¹,

Sievenpiper²,

Pauly³

et al. 2009

Canadian Medical Association Journal

102

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Contributors:David Jenkins had the original idea for the commentary and drafted the manuscript. John Sievenpiper gathered the references, produced the figure and helped draft the manuscript. Daniel Pauly and Ussif Rashid Sumaila drafted the sections on the decline of fisheries, socio-economic effects and aquaculture, and revised significant intellectual content related to the other sections. Cyril Kendall and Farley Mowat revised significant intellectual content. All of the authors approved the final manuscript submitted for publication.

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Effects of omega-3 fatty acids on coronary restenosis, intima–media thickness, and exercise tolerance: A systematic review

Cited by 56 publications

References 37 publications

Prevention of Cardiovascular Disease by Dietary n-3 Fatty Acid

Prevention of Cardiovascular Disease by Dietary n-3 Fatty Acid

Role of n-3 series polyunsaturated fatty acids in cardiovascular disease prevention

Are dietary recommendations for the use of fish oils sustainable?

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