Effects of normal blood pressure, prehypertension and hypertension on left ventricular diastolic function and aortic elastic properties

Abstract

Aortic elastic properties are significantly and LV diastolic function is slightly impaired in subjects with PHT, and impairment of aortic elasticity is as severe as that in hypertension.

Echocardiographic predictors of progression from prehypertension to hypertension

“…These structural changes may be qualitatively similar to the well described effects of hypertension on the peripheral circulation. As reported in hypertension, we have recently shown that LV diastolic function was slightly impaired in patients with PHT [15], and we have also found that CFR was significantly impaired in patients with PHT as compared to normotensive patients [6]; however, in patients with PHT, impairment of CFR was not as severely as that was in HT. Based on these data, we hypothesized that LV diastolic function parameters and CFR may be a marker to evaluate the risk of progression from PHT to HT.…”

“…All DTI recordings were obtained during normal respiration. A 5-mm sample volume was placed at the apical four-chamber view on the lateral corner of the mitral annulus and subsequently on the medial (or septal) corner [15]. The resulting velocities were recorded for 5-10 cardiac cycles at a sweep speed of 100 mm/s, and stored on video home system videotape for later playback and analysis.…”

Effects of resistance exercise training on resting and post-exercise forearm blood flow and wave reflection in overweight and obese women

“…It is important to note that participants in the previous study by Casey et al 21 were postmenopausal women with pre-hypertension and both conditions have been associated with increased arterial stiffness. 37,38 Furthermore, it has been suggested that estrogen improves endothelial function. 12,39 Therefore, it is feasible that the premenopausal status of our participants may have influenced the beneficial effect of RET on arm vasodilatory capacity.…”

Is It Time to Treat Prehypertension?

“…Aortic distensibility was significantly lower, and aortic stiffness index was significantly higher in both the hypertension and the prehypertension groups than in the control group. However, aortic elastic properties did not differ significantly between the prehypertension and hypertension groups (21).…”