Effects of new wound dressings on healing of thermal burns of the skin in acute radiation disease

Legeza, V I; Galenko-Yaroshevskii, V. P.; Zinoviev, E. V.; Paramonov, B. A.; Kreichman, G. S.; Turkovskii, I. I.; Gumenyuk, S. E.; Karnovich, A. G.; Хрипунов, А. К.

doi:10.1007/s10517-005-0029-4

Cited by 58 publications

(13 citation statements)

References 2 publications

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“…For example, Legeza et al created a microbial cellulose wound dressing for the treatment of thirddegree burns that was impregnated with superoxide dismutase (an antioxidant) or poviargol (an antibiotic) in order to augment its therapeutic properties. 55 A study by Ciechanska showed that an MC-chitosan composite material could be created during the synthesis of the cellulose membrane by adding chitosan to the culture medium. 56 In other words, the glucosamine and N-acetylglucosamine units were incorporated into the synthesized cellulose chains, which was demonstrated in another study by Shirai et al 57 Ciechanska claims that such a composite material has improved biological and physical properties.…”

Section: Microbial Cellulose As a Wound-healing Systemmentioning

confidence: 99%

The Future Prospects of Microbial Cellulose in Biomedical Applications

et al. 2006

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Microbial cellulose has proven to be a remarkably versatile biomaterial and can be used in wide variety of applied scientific endeavors, such as paper products, electronics, acoustics, and biomedical devices. In fact, biomedical devices recently have gained a significant amount of attention because of an increased interest in tissue-engineered products for both wound care and the regeneration of damaged or diseased organs. Due to its unique nanostructure and properties, microbial cellulose is a natural candidate for numerous medical and tissue-engineered applications. For example, a microbial cellulose membrane has been successfully used as a wound-healing device for severely damaged skin and as a small-diameter blood vessel replacement. The nonwoven ribbons of microbial cellulose microfibrils closely resemble the structure of native extracellullar matrices, suggesting that it could function as a scaffold for the production of many tissue-engineered constructs. In addition, microbial cellulose membranes, having a unique nanostructure, could have many other uses in wound healing and regenerative medicine, such as guided tissue regeneration (GTR), periodontal treatments, or as a replacement for dura mater (a membrane that surrounds brain tissue). In effect, microbial cellulose could function as a scaffold material for the regeneration of a wide variety of tissues, showing that it could eventually become an excellent platform technology for medicine. If microbial cellulose can be successfully mass produced, it will eventually become a vital biomaterial and will be used in the creation of a wide variety of medical devices and consumer products.

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Section: Microbial Cellulose As a Wound-healing Systemmentioning

confidence: 99%

The Future Prospects of Microbial Cellulose in Biomedical Applications

et al. 2006

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“…Bacterial cellulose impregnated membranes and poviargol, an antiseptic substance containing silver, was shown to accelerate the healing of irradiated wounds in an animal model [39]. A recent animal study has revealed that silver nanoparticles have the potential to promote wound healing through accelerated re-epithelialization and enhanced differentiation of fibroblasts.…”

Section: Future Aspects In the Treatment Of Irradiated Woundsmentioning

confidence: 99%

Wound healing after radiation therapy: Review of the literature

et al. 2012

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Radiation therapy is an established modality in the treatment of head and neck cancer patients. Compromised wound healing in irradiated tissues is a common and challenging clinical problem. The pathophysiology and underlying cellular mechanisms including the complex interaction of cytokines and growth factors are still not understood completely. In this review, the current state of research regarding the pathomechanisms of compromised wound healing in irradiated tissues is presented. Current and possible future treatment strategies are critically reviewed.

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“…Legeza et al [75] produced a BC wound dressing for the treatment of third degree burns that is impregnated with superoxide dismutase (an antioxidant) or poviargol (an antibiotic).…”

Section: Bc Based Structures For Biomedical Applicationsmentioning

confidence: 99%

Biocompatibility of Bacterial Cellulose Based Biomaterials

Torres

Commeaux

Troncoso

2012

JFB

223

139

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Some bacteria can synthesize cellulose when they are cultivated under adequate conditions. These bacteria produce a mat of cellulose on the top of the culture medium, which is formed by a three-dimensional coherent network of pure cellulose nanofibers. Bacterial cellulose (BC) has been widely used in different fields, such as the paper industry, electronics and tissue engineering due to its remarkable mechanical properties, conformability and porosity. Nanocomposites based on BC have received much attention, because of the possibility of combining the good properties of BC with other materials for specific applications. BC nanocomposites can be processed either in a static or an agitated medium. The fabrication of BC nanocomposites in static media can be carried out while keeping the original mat structure obtained after the synthesis to form the final nanocomposite or by altering the culture media with other components. The present article reviews the issue of biocompatibility of BC and BC nanocomposites. Biomedical aspects, such as surface modification for improving cell adhesion, in vitro and in vivo studies are given along with details concerning the physics of network formation and the changes that occur in the cellulose networks due to the presence of a second phase. The relevance of biocompatibility studies for the development of BC-based materials in bone, skin and cardiovascular tissue engineering is also discussed.

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Effects of new wound dressings on healing of thermal burns of the skin in acute radiation disease

Cited by 58 publications

References 2 publications

The Future Prospects of Microbial Cellulose in Biomedical Applications

The Future Prospects of Microbial Cellulose in Biomedical Applications

Wound healing after radiation therapy: Review of the literature

Biocompatibility of Bacterial Cellulose Based Biomaterials

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