Effects of milk diet on gastrointestinal absorption of cadmium in adult mice

Effect of Age and Diet on Renal Cadmium Retention in Rats

“…Dietary factors are known to be important in cadmium metabolism, especially in determining absorption from the gastrointestinal tract (29,30). Our preliminary data indicate that dietary factors not only influence absorption but may also influence distribution of cadmium in the body.…”

Effect of Age and Diet on Renal Cadmium Retention in Rats

“…Dietary factors are known to be important in cadmium metabolism, especially in determining absorption from the gastrointestinal tract (29,30). Our preliminary data indicate that dietary factors not only influence absorption but may also influence distribution of cadmium in the body.…”

Intestinal Absorption and Metabolism of Xenobiotics

“…Recently Engstrom and Nordburg looked at the effect of milk diet on gastrointestinal absorption of cadmium in adult mice. A markedly higher body retention of 109CdC12 was observed in animals given a milk diet compared to other groups on laboratory chow (20).…”

Bioavailability of Cadmium in Food and Water: A Case Study on the Derivation of Relative Bioavailability Factors for Inorganics and Their Relevance to the Reference Dose

“…Support for application of this concept to cadmium is provided by the studies of Andersen et al (1992), Engstrom and Nordberg ( 1978), Kello and Kostial ( 1977), and Rabar and Kostial (1981). In each of these studies, the medium of administration of :1 cadmium remained the same for each group of animals (water by gavage), but the ad libitum food varied in composition among the different groups.…”

“…8, 8.3, 7.3, and 7.8% of the initial dose in rats fed rat chow, ..tinned luncheon meat," whole wheat bread, or milk, respectively. Two studies have reported higher retention of cadmium (estimated 14 and 28 days after dosing) after a single gavage dose of radiolabeled CdO2 in water in aduh mice fed milk (5.6 and ~4.0%) than that in adult mice fed standard rat chow (0.3 and ~ 1.5%) (Kello and Kostial, 1977;Engstrom and Nordberg, 1978). In all four of the above studies, the medium of administration for all groups was water, while the type of food ingested was varied among the different groups.…”

Effect of Age and Diet on Renal Cadmium Retention in Rats

“…Dietary factors are known to be important in cadmium metabolism, especially in determining absorption from the gastrointestinal tract (29,30). Our preliminary data indicate that dietary factors not only influence absorption but may also influence distribution of cadmium in the body.…”

Intestinal Absorption and Metabolism of Xenobiotics

“…Recently Engstrom and Nordburg looked at the effect of milk diet on gastrointestinal absorption of cadmium in adult mice. A markedly higher body retention of 109CdC12 was observed in animals given a milk diet compared to other groups on laboratory chow (20).…”

Bioavailability of Cadmium in Food and Water: A Case Study on the Derivation of Relative Bioavailability Factors for Inorganics and Their Relevance to the Reference Dose

“…Support for application of this concept to cadmium is provided by the studies of Andersen et al (1992), Engstrom and Nordberg ( 1978), Kello and Kostial ( 1977), and Rabar and Kostial (1981). In each of these studies, the medium of administration of :1 cadmium remained the same for each group of animals (water by gavage), but the ad libitum food varied in composition among the different groups.…”

“…8, 8.3, 7.3, and 7.8% of the initial dose in rats fed rat chow, ..tinned luncheon meat," whole wheat bread, or milk, respectively. Two studies have reported higher retention of cadmium (estimated 14 and 28 days after dosing) after a single gavage dose of radiolabeled CdO2 in water in aduh mice fed milk (5.6 and ~4.0%) than that in adult mice fed standard rat chow (0.3 and ~ 1.5%) (Kello and Kostial, 1977;Engstrom and Nordberg, 1978). In all four of the above studies, the medium of administration for all groups was water, while the type of food ingested was varied among the different groups.…”

Effect of Age and Diet on Renal Cadmium Retention in Rats

“…Dietary factors are known to be important in cadmium metabolism, especially in determining absorption from the gastrointestinal tract (29,30). Our preliminary data indicate that dietary factors not only influence absorption but may also influence distribution of cadmium in the body.…”

Intestinal Absorption and Metabolism of Xenobiotics

“…Recently Engstrom and Nordburg looked at the effect of milk diet on gastrointestinal absorption of cadmium in adult mice. A markedly higher body retention of 109CdC12 was observed in animals given a milk diet compared to other groups on laboratory chow (20).…”

Bioavailability of Cadmium in Food and Water: A Case Study on the Derivation of Relative Bioavailability Factors for Inorganics and Their Relevance to the Reference Dose

“…Support for application of this concept to cadmium is provided by the studies of Andersen et al (1992), Engstrom and Nordberg ( 1978), Kello and Kostial ( 1977), and Rabar and Kostial (1981). In each of these studies, the medium of administration of :1 cadmium remained the same for each group of animals (water by gavage), but the ad libitum food varied in composition among the different groups.…”

“…8, 8.3, 7.3, and 7.8% of the initial dose in rats fed rat chow, ..tinned luncheon meat," whole wheat bread, or milk, respectively. Two studies have reported higher retention of cadmium (estimated 14 and 28 days after dosing) after a single gavage dose of radiolabeled CdO2 in water in aduh mice fed milk (5.6 and ~4.0%) than that in adult mice fed standard rat chow (0.3 and ~ 1.5%) (Kello and Kostial, 1977;Engstrom and Nordberg, 1978). In all four of the above studies, the medium of administration for all groups was water, while the type of food ingested was varied among the different groups.…”