Effects of men and recipients’ age on the reproductive outcome of an oocyte donation program

Abstract

Present study suggests that age has a detrimental effect on the reproductive outcome of oocyte donation cycles when both men and recipient are > or = 39 years old.

Effect of male age on the outcome of in vitro fertilization: oocyte donation as a model

“…Also, when the cycles were divided into two groups according to whether a clinical pregnancy was achieved, or according to whether a live birth was achieved, no significant difference was found in male age between the groups, indicating that male aging would not lead to severe influence on fertilization or embryo development in vitro, which was similar to studies of other authors [8][9][10], but disagreed with founding of other authors [11,12].…”

“…Some studies from Europe and USA found that the increase of male age may lead to elevation of miscarriage rate after ART [4,[11][12][13]. We also found that male aging may be related to the increase of pregnancy loss in the first trimester of pregnancy.…”

Effect of paternal age on reproductive outcomes in oocyte donation model: a systematic review

“…For the comparisons of interrater reliability, the kappa coefficient was 0.86 during the abstract review (95% confidence interval [CI] 0.75-0.97) and 0.92 in the full-text stage (95% CI, 0.76-1.0). Finally, of 425 initial references, twelve manuscripts encompassing 12,538 oocyte donation cases were included in the review (10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21). Table 1 summarizes the characteristics of the selected studies.…”

The effect of age on the expression of apoptosis biomarkers in human spermatozoa

“…Reports on the impact of male age on the outcome of assisted reproductive technologies (ART) using the donor egg model are conflicting (20)(21)(22)(23)(24)(25). This model allows controlling for the effects of variation of oocyte quality by female age.…”