Effects of lower limb neurodynamic mobilization on intraneural fluid dispersion of the fourth lumbar nerve root: an unembalmed cadaveric investigation

Gilbert, Kerry K.; Smith, Michael; Sobczak, Stéphane; James, C. Roger; Sizer, Phillip Pt; Brismée, Jean Michel

doi:10.1179/2042618615y.0000000009

Cited by 27 publications

(21 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Considering the chronic nature of the symptoms presented by the participants with sciatica, it is possible that the affected sciatic nerve has some of these physiopathologic alterations. As neurodynamic techniques have been associated with intraneural blood flow facilitation, and nerve viscoelastic stress relaxation, we hypothesize that the combination of these effects explains the sciatic stiffness decrease observed in the sciatica group (and not in the healthy group) after the intervention. Nevertheless, it should be noted that the effects of slump neurodynamics were not correlated with self‐reported measures of pain, disability, and also the duration of symptoms.…”

Section: Discussionmentioning

confidence: 91%

Shear Wave Elastographic Investigation of the Immediate Effects of Slump Neurodynamics in People With Sciatica

Neto

Freitas

Andrade

et al. 2019

J of Ultrasound Medicine

View full text Add to dashboard Cite

Objectives Neurodynamic techniques are often used to treat people with sciatica pain, but their mechanical effects on the sciatic nerve are unknown. Shear wave elastography (SWE) has been shown to effectively estimate the stiffness of peripheral nerves in real time. The aim of this study was to use SWE to assess the effects of slump neurodynamics in the sciatic stiffness of people with sciatica. Methods Sixteen participants volunteered for this study. The sciatic stiffness of 8 patients with unilateral chronic sciatica and 8 healthy control participants was measured by SWE, with the participants in a prone position and during a dynamic condition (ie, ankle dorsiflexion). These measurements were performed before and immediately after the neurodynamic intervention, which consisted of a static slump position applied to the symptomatic limb of the patients with sciatica and in a randomly chosen limb of the healthy participants. Results The 8 patients with sciatica included 6 male and 2 female patients, and the 8 healthy control participants included 5 male and 3 female volunteers. Slump neurodynamics resulted in an immediate decrease in the sciatic nerve stiffness of the symptomatic limb in people with sciatica by 16.1% (effect size = 0.65; P = .019). The intervention showed no significant changes in the sciatic nerve stiffness of the healthy participants (effect size = 0.05; P = .754). Conclusions Slump neurodynamics have the potential of decreasing the sciatic nerve stiffness in people with sciatica, and this effect can be quantified by SWE, which may provide valuable information for health professionals.

show abstract

Section: Discussionmentioning

confidence: 91%

Shear Wave Elastographic Investigation of the Immediate Effects of Slump Neurodynamics in People With Sciatica

Neto

Freitas

Andrade

et al. 2019

J of Ultrasound Medicine

View full text Add to dashboard Cite

show abstract

“…Overall, the therapeutic effects of the nerve mobilization could be accounted for by reduction of physical stress through the movements of the nerves (17,18) and intraneural fluid dispersion (19,20), normalization of sensory axons excitability (25), and promotion of nerve regeneration by stimulating expression of neural growth factor and myelin protein zero (38,39). As a pilot study, the methodology had several limitations such as sample size, subjects' homogeneity and the length of the follow-up period.…”

Section: N Discussionmentioning

confidence: 99%

“…The nerve mobilisation produces from -7% to +6% changes in length of the nerve by excursion and strain (17,18). Besides the physical movements on the nerves, the mobilisation may disperse intraneural fluid, and help alleviate intraneural oedema after injury (19,20). Clinically, this technique could be applied in clinical examinations and as active or passive nerve mobilization therapeutic exercises (21,22).…”

Section: Methodsmentioning

confidence: 99%

The effect of nerve mobilization exercise in patients with rheumatoid arthritis: a pilot study

Xia²,

Leung³

2017

Reumatismo

View full text Add to dashboard Cite

SUMMARYRheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic inflammation of the joints. The neurogenic inflammatory mechanism plays an important role in the inflammatory process of RA, and pathological changes in neural tissues in RA have also been noted. We aim to investigate treatment of the nervous system to relieve joint pain and inflammation in RA. Nerve mobilization, a nervous system-specific therapeutic exercise, was applied on RA patients to determine the effect of nerve mobilization on joint inflammation. Twelve RA patients were recruited from the community and were randomised into an experimental and a control group. In the experimental group, the subjects were taught a set of nerve mobilization exercises while the subjects in the control group were taught a set of gentle joint mobilization exercises. Both groups were instructed to practice the exercises daily. After a 4-week period, their RA pain scale (RAPS) and pain scores were examined, as well as the C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Subjects in the experimental group showed improvements in RAPS and pain scores after 4 weeks of nerve mobilization exercises, while CRP and ESR values remained unaffected. These preliminary data showed that nerve mobilization exercises might be beneficial in controlling joint pain in RA patients. Reumatismo, 2017; 69 (3): 111-118 n INTRODUCTION R heumatoid arthritis (RA) is one of the most prevalent chronic autoimmune diseases. The symptoms of RA are characterized by joint inflammation and deformities that are associated with pain and functional disability (1). The aetiology of RA remains unclear, but an increasing number of investigations have provided evidence that disease perpetuation could be due to a mixture of both immunogenic (1) and neurogenic (2, 3) inflammation. The mechanism of neurogenic inflammation has been described as an inflammation that is initiated by the nervous system (4-6). The neurogenic inflammation is triggered in the tissues by the cutaneous nerves (4, 7-10). The evidence of neurogenic inflammation in RA is supported by a small but significant number of tyrosine hydroxylase-positive sympathetic nerve fibres, which have a negative correlation with the inflammation index, a large number of substance P-positive nerve fibres (11) and immunoreactive sensory nerve fibres with calcitonin gene-related peptide (CGRP) (12). The current treatment algorithms for RA involve the use of both traditional and biological disease-modifying antirheumatic drugs (DMARDs) to control the disease (13). Physical treatments are also beneficial for patients to optimize physical functions, decreasing pain and improving quality of life (14-16). A paradigm is named as neurodynamic, which is a series of movements that produce physiological and mechanical events in the nervous system. They are used in physical testing to gain a response to the mechanical performance and sensitivity of the nervous sys- Key words: CRP; ESR; Nerve mobilisation; Neurogenic inflammation...

show abstract

“…Coppieters y cols. (36,37) mencionan que, al aumentar el deslizamiento de los nervios con respecto al tejido circundante, aumenta la movilidad del nervio y la movilización de los fluidos intraneurales, pudiendo así aliviar los síntomas (38,39). Butler, Gifford y Shacklock (40)(41)(42) agregan que la movilización del tejido neural mejora la conducción nerviosa y el flujo sanguíneo del nervio.…”

Section: Cómo Podría Funcionar La Intervenciónunclassified

Efectividad de la movilización neurodinámica en el dolor y funcionalidad en sujetos con el síndrome del túnel carpiano: revisión sistemática

Cornejo¹,

Quintanilla²,

Cassis³

et al. 2017

Rev. Soc. Esp. Dolor.

View full text Add to dashboard Cite

Este es un archivo PDF de un manuscrito inédito que ha sido aceptado para su publicación en la Revista de la Sociedad Española del Dolor. Como un servicio a nuestros clientes estamos proporcionando esta primera versión del manuscrito en estado de prepublicación. El manuscrito será sometido a la corrección de estilo final, composición y revisión de la prueba resultante antes de que se publique en su forma final. Tenga en cuenta que durante el proceso de producción se pueden dar errores lo que podría afectar el contenido final. El copyright y todos los derechos legales que se aplican al artículo pertenecen a la

show abstract

Effects of lower limb neurodynamic mobilization on intraneural fluid dispersion of the fourth lumbar nerve root: an unembalmed cadaveric investigation

Cited by 27 publications

References 57 publications

Shear Wave Elastographic Investigation of the Immediate Effects of Slump Neurodynamics in People With Sciatica

Shear Wave Elastographic Investigation of the Immediate Effects of Slump Neurodynamics in People With Sciatica

The effect of nerve mobilization exercise in patients with rheumatoid arthritis: a pilot study

Efectividad de la movilización neurodinámica en el dolor y funcionalidad en sujetos con el síndrome del túnel carpiano: revisión sistemática

Contact Info

Product

Resources

About