Effects of long-term exercise training on cardiac baroreflex sensitivity in patients with coronary artery disease: a randomized controlled trial

Mameletzi, Dimitra; Kouidi, Evangelia; Κουτλιάνος, Νικόλαος; Deligiannis, Asterios

doi:10.1177/0269215510380825

Cited by 25 publications

(23 citation statements)

References 51 publications

(87 reference statements)

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“…It also has been reported that home-based exercise training programs are beneficial in maintaining exercise capacity and reducing healthcare costs in low-risk patients after MI. 236, 237 There has been increasing evidence from largescale epidemiological studies and RCTs on the safety of exercise training and the role of comprehensive programs for elderly patients with cardiovascular diseases. 228,238-241 Elderly patients should be strongly encouraged to participate in cardiac rehabilitation programs.…”

Section: Table 30 Characteristics Of Elderly Patients With Acute Myomentioning

confidence: 99%

Guidelines for Rehabilitation in Patients With Cardiovascular Disease (JCS 2012)

2014

Circ J

237

150

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Section: Table 30 Characteristics Of Elderly Patients With Acute Myomentioning

confidence: 99%

Guidelines for Rehabilitation in Patients With Cardiovascular Disease (JCS 2012)

2014

Circ J

237

150

View full text Add to dashboard Cite

“…9 Studies have also shown that baroreflex sensitivity was improved following long-term chronic exercise training in a diseased population. 10,11 However, to date no study has examined the effects of short-term exercise on arterial stiffness, limb blood flow and baroreflex sensitivity in young FH þ men. Thus, the purpose of this study was to examine the effects of 4 weeks of moderate intensity aerobic exercise on peripheral and central vascular variables, which include AIx, forearm and leg blood flow (LBF), and baroreflex sensitivity in normotensive young FH þ men.…”

Section: Introductionmentioning

confidence: 99%

The effect of 4 weeks of aerobic exercise on vascular and baroreflex function of young men with a family history of hypertension

Goldberg

Boutcher

2011

J Hum Hypertens

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The effect of short-term aerobic exercise on vascular function of young individuals with a family history of hypertension was investigated. Thirty young men with a family history of hypertension were randomly assigned to either an exercise (n ¼ 15) or control (n ¼ 15) group. Exercise subjects performed 30 min of supervised cycle training at 65% of their maximal oxygen uptake ( . VO 2max ), three times per week for 4 weeks. Control subjects were asked to maintain their normal levels of physical activity. Peak leg and forearm blood flow were assessed using plethysmography and was determined as the highest blood flow following 5 min of reactive hyperemia. Cardiopulmonary baroreceptor (CPBR) sensitivity was measured using lower body negative pressure (LBNP) for 5 min at À20 mm Hg. CPBR was determined by calculating change of stroke volume and forearm vascular resistance at baseline and during LBNP. Carotid baroreceptor (CBR) sensitivity was assessed using neck suction at À20, À40, À60 and À80 mm Hg pressures, and was determined from RR interval divided by systolic blood pressure. Augmentation index (AIx), a measure of arterial stiffness, was assessed using applanation tonometry and was calculated as the ratio of augmented pressure and pulse pressure. The major findings were that the exercise group showed increase in leg vasodilation, reduction in AIx and increase in .VO 2max compared with the control group (Po0.05). However, there was no significant change for CPBR and CBR. A short-term moderate-intensity aerobic exercise intervention in young men with a family history of hypertension significantly reduced arterial stiffness and increased aerobic fitness.

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Section: Discussionmentioning

confidence: 88%

“…In fact, the benefits of regular exercise on autonomic regulation have been supported by a growing number of studies, showing similar improvements in HRV indexes in time and frequency domain after physical training in healthy elderly, cardiac, hypertensive, diabetic patients on HD and RT. 13,[15][16][17] The vagal modulation observed in the AG group may be due to increased sensitivity of muscarinic acetylcholine receptors, responsible for the activation of cholinergic pathway. 18 Positive adjustment of the baroreflex mechanism was found in the physical exercise intervention group in a study conducted by Kouidi et al, 14 suggesting that these changes may lead to better cardiovascular prognosis of renal transplant.…”

Section: Discussionmentioning

confidence: 99%

Autonomic modulation analysis in active and sedentary kidney transplanted recipients

Dias

Azoubel²,

Costa

et al. 2015

Clin Exp Pharma Physio

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Modulation of the autonomic nervous system on heart rate can be compromised in chronic kidney disease and may result in changes in the frequency and duration of the cardiac cycle. The aim of this study was to evaluate autonomic modulation in active and sedentary renal transplant recipients. Twenty renal-transplanted individuals were analyzed at the Centro de Prevenção de Doenças Renais (Kidney Disease Education Centre), in the academic hospital of Universidade Federal do Maranhão, and were divided into the active group (AG) and the sedentary group (SG). The AG comprised of six men and four women (age 43.10 ± 13.02) and was in regular concurrent training intervention for 8 weeks, while the SG was composed of three men and seven women (age 36.8 ± 9.26). Analysis of heart rate (HR) variability in time and frequency domain demonstrated that HR mean values in the SG and AG were 787.32 ± 79.60 and 870 ± 106.66 ms, respectively. Differences were observed in the time domain and frequency domain. The total index of low frequency and high frequency showed no differences between the SG and AG. Biochemical variables presented significantly lower levels after 8 weeks of training. Higher heart rate variability in the time domain and greater vagal modulation was observed in the AG. The AG ad greater vagal modulation when compared to the SG, with removal of the sympathetic and increased parasympathetic in the behaviour was confirmed by sympatho-vagal balance. The AG also presented significant improvements in the frequency domain.

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Effects of long-term exercise training on cardiac baroreflex sensitivity in patients with coronary artery disease: a randomized controlled trial

Abstract: The results suggest that long-term exercise training leads to beneficial effects on baroreflex activity and cardiorespiratory performance in coronary patients, and thus could constitute an efficient nonpharmacological intervention in this population.

Cited by 25 publications

References 51 publications

Guidelines for Rehabilitation in Patients With Cardiovascular Disease (JCS 2012)

Guidelines for Rehabilitation in Patients With Cardiovascular Disease (JCS 2012)

The effect of 4 weeks of aerobic exercise on vascular and baroreflex function of young men with a family history of hypertension

Autonomic modulation analysis in active and sedentary kidney transplanted recipients

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