Effects of levamisole and ranitidine on antibody‐forming responses induced by killed Mycoplasma vaccine antigens in Saanen goats

Temizel, Ethem Mutlu; Onat, K.; Mecitoğlu, Zafer; Kasap, Sevim; Göçmen, Hüban; Ülgen, Mihriban

doi:10.1136/vr.101098

Veterinary Record

2012

DOI: 10.1136/vr.101098

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Effects of levamisole and ranitidine on antibody‐forming responses induced by killed Mycoplasma vaccine antigens in Saanen goats

Ethem Mutlu Temizel

K. Onat

Zafer Mecitoğlu

et al.

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2017

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“…It belongs to the class of synthetic imidazothiazole derivative. Levamisole refurbishes cell mediated immune response by potentiating the rate of Tlymphocyte differentiation and proliferation of macrophages (Temizel et al 2012) and stimulating phagocytosis by monocytes. The present investigation was therefore undertaken to find out the effect of Levamisole treatment on amelioration of vaccination stress on semen production performance in cross bred bulls.…”

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Levamisole as an immunomodulator to ameliorate vaccination stress in crossbred bulls

Rao

Mohanty

Bhakat

2017

Indian J of Anim Sci

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Present study was planned on 8 crossbred bulls (144 ejaculates) to study effect of levamisole on vaccination stress. All the bulls were vaccinated with Trio-vac vaccine as per routine schedule of the farm. In treatment group (4 bulls) levamisole was injected 1 week prior to vaccination, whereas in control normal saline was injected. Semen ejaculates were evaluated during pre-vaccination (1 week) and post-vaccination (8 week) period. Results revealed significantly lesser reaction time, sperm abnormalities and higher sperm concentration (million/ml), total motile spermatozoa (×106), total live spermatozoa/ml (×106), total sperm (×106) and total dose harvested in treated group. Individual motility, mass motility, NEC, HOST and IA (%) was higher in levamisole treated group, but it was not statistically significant. Vaccination stress was evident in both group, however the stress was prominent in control. Level of serum Zn and immunoglobulin improved significantly in treated bulls. Levamisole treatment in vaccinated bulls has positive effect to some extent in amelioration of stress.

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confidence: 99%

Levamisole as an immunomodulator to ameliorate vaccination stress in crossbred bulls

Rao

Mohanty

Bhakat

2017

Indian J of Anim Sci

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Effects of levamisole and ranitidine on antibody‐forming responses induced by killed Mycoplasma vaccine antigens in Saanen goats

Cited by 1 publication

References 17 publications

Levamisole as an immunomodulator to ameliorate vaccination stress in crossbred bulls

Levamisole as an immunomodulator to ameliorate vaccination stress in crossbred bulls

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