Effects of laying breeder hens dietary β-carotene, curcumin, allicin, and sodium butyrate supplementation on the growth performance, immunity, and jejunum morphology of their offspring chicks

Abstract

This study evaluated the growth performance, immunity, and jejunum morphology of chicks hatched from laying breeder hens given dietary additive supplementation, as well as chicks receiving direct antibiotic supplementation in early life. Hy-line breeder hens were allotted to 2 groups with 3 replicates. A control group (CON) was fed a basal diet, and the treatment group (CCAB) received β-carotene, curcumin, allicin, and sodium butyrate in addition to basal diet for 5 wk. Breeder–hen eggs were collected and hatched. The chicks hatched from the CON group were assigned to 2 treatments: a chick control group (cCON) and a chick treatment group (Cipro) given ciprofloxacin lactate into drinking water; the cCON group, Cipro group, and the chicks hatched from the CCAB group (cCCAB) were fed the same diet for 4 wk. The results demonstrated that there were significant differences between the CON and CCAB groups in the serum levels of IgA, IgG, IgM (triple P < 0.01), lysozyme ( P < 0.05), and β-defensin ( P < 0.05). The body weights of the cCCAB group's chicks increased at 1, 7, and 28 D of age ( P < 0.05, P < 0.05, P < 0.01, respectively), and those of the Cipro group's chicks increased at 7 and 21 D of age ( P < 0.01, P < 0.05). The tibial lengths of the cCCAB group's chicks increased at 1, 7, 14, 21, and 28 D of age ( P < 0.01, P < 0.05, triple P < 0.01), and the lengths in the Cipro group increased at 7 and 14 D of age ( P < 0.01, P < 0.01). Intestinal development, including intestinal length, jejunum morphology, and IgA positive cells, helps to explain these results. The breeder eggs from the CCAB group had higher IgG ( P < 0.05) and IgM ( P < 0.05) levels in the egg whites and higher IgA, IgG, and IgM levels (triple P < 0.01) in the egg yolks. In conclusion, β-carotene, curcumin, allicin, and sodium butyrate supplementation of laying breeder hen diets produced more advantages in growth performance and intestinal development in offspring than in chicks directly supplemented with antibiotics.

Effects on Intestinal Mucosal Morphology, Productive Parameters and Microbiota Composition after Supplementation with Fermented Defatted Alperujo (FDA) in Laying Hens

“…The majority of these studies focused on the small intestine, mainly the jejunum mucosa, with only a few evaluating the duodenum [30][31][32][33][34][35][36][37], despite its very high absorption potential [38]. In one case, supplementation with bamboo vinegar or polyunsaturated fatty acid from an extruded flax product resulted in a significant increase in duodenal villi height in aged hens, suggesting that diet composition affects the duodenal mucosal structure [29,36].…”

Effects of laying breeder hens dietary β-carotene, curcumin, allicin, and sodium butyrate supplementation on the jejunal microbiota and immune response of their offspring chicks

“…The methods of bird management and experimental design have been published in detail in our previous study ( Gong et al., 2020 ). Briefly, a total of 162 Hy-Line Brown laying breeder hens were randomly allotted to 2 groups (a control group [ CON ] and the β-carotene, curcumin, allicin, and sodium butyrate supplementation group [ CCAB ]).…”

“…The chicks were fed for 4 wk. The detailed chick-brooding management, and basal diet composition of experimental laying breeder hens and chicks are listed in Supplementary Tables 1 and 2 , and we declare that these 2 tables have been published in our previous study ( Gong et al., 2020 ).…”

“…Moreover, we noticed that chicks supplemented with ciprofloxacin lactate demonstrated enhanced growth performance before 14 D of age, but the promotion effects decreased when ciprofloxacin lactate administration was extended, which was also explained with regard to the changed jejunal immune development and morphology. Hence, we suggest that the variation in growth performance between groups was associated with their intestinal immunity ( Gong et al., 2020 ).…”

Alpha‐lipoic acid improves the reproduction performance of breeder hens during the late egg‐laying period

“…It works as an integral component of mitochondria, which can chelate metals, quench specific radicals and regenerate other antioxidants (Liu, 2008;Ma et al, 2015). In polycystic ovary syndrome women, ALA improves reproductive function and metabolic parameters (Cappelli, Di Sabatino, Musacchio, & De Leo, 2013;Genazzani et al, 2018). ALA increases follicular antioxidant capacity levels and finally improves the developmental competence of preantral follicles in vitro (Zoheir et al, 2017).…”