Effects of laser guided by optic fiber into rat brain on conditioned avoidance response and brain chemistry

ShenZheng,; Xiaojian,; Lin, Songyi; Wang, Lihua

doi:10.1002/lsm.1900020306

Cited by 9 publications

(1 citation statement)

References 19 publications

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“…(1) This change is not due to heating because it occurs before there is a measurable increase in temperature. Very brief irradiation with a ruby laser (694 nm) results in a large increase in acetylcholine concentration in an isolate vertebrate nerve preparation (2) and introduction of a helium-neon laser (625 nm) into rodent brain via fibre optics procedures behavioural (3) and neurochemical changes. (4) Irradiation of peripheral nerves in humans with a low power helium neon laser produces an evoked potential (5) and depresses spinal reflexes.…”

Section: Introductionmentioning

confidence: 99%

Suppression of Hippocampal Epileptiform Activity in Vitro After Laser Exposure

Walker

Swartzwelder

Bondy³

2004

LASER THERAPY

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Extracellular field potentials were recorded in the stratum pyramidale of CA3 in hippocampal slices prepared from male Sprague-Dawley rats. Electrical stimuli were delivered to s. radiatum of CA3. After stable responses were established, stimulus trains were delivered every 5 mm until stable triggered and spontaneous population bursts were elicited. The slices were then irradiated with a low power (25 mW) argon laser. No changes in the morphology or number of epileptiform bursts were found while the laser was on. However, when the laser was turned off, there was a highly significant reduction in frequency and morphology of bursts. These results indicate that exposure to light alters epileptiform activity within the hippocampus in vitro, and provides evidence indicating that the central nervous system is photosensitive.

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