“…In the past few years, only 12 studies have provided experimental data on the biological impacts of PSC-related chemicals (Table and Figure ). Two fishes (zebrafish and Japanese medaka), ,− a water flea, ,,− a phytoplankton, a chironomus, a nematode, , and bacteria were selected as test species. Three soil plants and soil bacteria , were investigated to evaluate the soil ecotoxicology, and five human cell lines (A549 cell, SH-SY5Y cell, Caco-2/TC7 cell, Beas2B cell, and HepG2 cell) and mouse neurons were assessed via in vitro assay. ,, Even though the aquatic toxicity data accumulated were more than those on soil toxicity and cytotoxicity, the number of reports is still very limited.…”