Effects of inhaled fine dust on lung tissue changes and antibody response induced by spores of opportunistic fungi in goats

Purdy, Charles W.; Layton, Robert C.; Straus, David C.; Ayers, J. R.

doi:10.2460/ajvr.69.4.501

Cited by 3 publications

(1 citation statement)

References 23 publications

(34 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It appears that the common denominator of CAFO dust is endotoxin found in both 10-and 2.5-μm particles, which trigger local and systemic inflammatory reactions upon inhalation (Purdy et al, 2004b). The smaller particles can be inspired deep into the lung alveoli and affect the immune system (Purdy et al, 2008). In addition to endotoxin, allergens, microbial pathogens, bacterial toxins, fungal spores, and mycotoxins can be attached to dust particles that, when inhaled, can cause dramatic local and systemic inflammatory reactions or, in some cases, infections.…”

Section: Discussionmentioning

confidence: 99%

Ambient and indoor particulate aerosols generated by dairies in the southern High Plains

Purdy

Clark

Straus

2009

Journal of Dairy Science

View full text Add to dashboard Cite

The objectives were to quantify and size ambient aerosolized dust in and around the facilities of 4 southern High Plains dairies of New Mexico and to determine where health of workers might be vulnerable to particulate aerosols, based on aerosol concentrations that exceed national air quality standards. Ambient dust air samples were collected upwind (background) and downwind of 3 dairy location sites (loafing pen boundary, commodity, and compost field). The indoor milking parlor, a fourth site, was monitored immediately upwind and downwind. Aerosolized particulate samples were collected using high-volume sequential reference air samplers, laser aerosol monitors, and cyclone air samplers. The overall (main effects and estimable interactions) statistical general linear model statement for particulate matter (PM(10); particulate matter with an aerodynamic diameter of up to 10 microm) and PM(2.5) resulted in a greater mean concentration of dust in the winter (PM(10) = 97.4 +/- 4.4 microg/m(3); PM(2.5) = 32.6 +/- 2.6 microg/m(3)) compared with the summer (PM(10) = 71.9 +/- 5.0 microg/m(3); PM(2.5) = 18.1 +/- 1.2 microg/m(3)). The upwind and downwind boundary PM(10) concentrations were significantly higher in the winter (upwind = 64.3 +/- 9.5 microg/m(3); downwind = 119.8 +/- 13.0 microg/m(3)) compared with the summer (upwind = 35.2 +/- 7.5 microg/m(3); downwind = 66.8 +/- 11.8 microg/m(3)). The milking parlor PM(10) and PM(2.5) concentration data were significantly higher in the winter (PM(10) = 119.5 +/- 5.8 microg/m(3); PM(2.5) = 55.3 +/- 5.8microg/m(3)) compared with the summer (PM(10) = 88.6.0 +/- 5.8 microg/m(3); PM(2.5) = 21.0 +/- 2.1 microg/m(3)). Personnel should be protected from high aerosol concentrations found at the commodity barn, compost field, and milking parlor during the winter.

show abstract

Section: Discussionmentioning

confidence: 99%

Ambient and indoor particulate aerosols generated by dairies in the southern High Plains

Purdy

Clark

Straus

2009

Journal of Dairy Science

View full text Add to dashboard Cite

show abstract

Detection of 3-nitropropionic acid and cytotoxicity inMucor circinelloides

et al. 2008

View full text Add to dashboard Cite

Mucorales are regarded as the aetiological agents of Mucormycosis. Their capabilities to produce mycotoxins are not profoundly investigated, in contrast to those of the fungi from the generaPenicillium, Aspergillus, orFusarium. The aim of this study was to isolate and identify fungi of the order Mucorales and investigate mycotoxins production. Twelve samples of visibly moulded grass silage and eight samples of damaged whole crop maize silage were analysed. Malt extract agar plates were used for sub cultivation. Three fungal species of the order Mucorales were isolated from grass silage, which were identified by their macro-and micro-morphology asAbsidia corymbifera, Mucor circinelloides andRhizopus stolonifer. The cytotoxicity ofMucor circinelloides extract was analysed using the cytotoxicity test (MTT assay) and the result, showed a low cytotoxicity. Additionally extracts fromAbsidia corymbifera, Mucor circinelloides andRhizopus stolonifer were tested for mycotoxin-production using an LC/MS/MS-based multimycotoxin method. 3-nitropropionic acid was detected in the culture extract ofMucor circinelloides.

show abstract

Associations of PM2.5 and aspergillosis: ambient fine particulate air pollution and population-based big data linkage analyses

Liu

Tsan

Chan

et al. 2018

J Ambient Intell Human Comput

View full text Add to dashboard Cite

Effects of inhaled fine dust on lung tissue changes and antibody response induced by spores of opportunistic fungi in goats

Abstract: Fine dust inhalation appeared to decrease the ability of goats to successfully clear fungal spores from the lungs following intratracheal inoculation.

Cited by 3 publications

References 23 publications

Ambient and indoor particulate aerosols generated by dairies in the southern High Plains

Ambient and indoor particulate aerosols generated by dairies in the southern High Plains

Detection of 3-nitropropionic acid and cytotoxicity inMucor circinelloides

Associations of PM2.5 and aspergillosis: ambient fine particulate air pollution and population-based big data linkage analyses

Contact Info

Product

Resources

About