Effects of Influenza on Pregnancy

Czeizel, Andr̀ew E.; G, Tusnády; Domány, Z; Borsy, Kinga

doi:10.1016/s0140-6736(67)91698-4

Cited by 3 publications

(2 citation statements)

References 12 publications

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“…It is a generally accepted opinion that influenza may be associated with more severe symptoms and a higher mortality in pregnant women, mainly during the last trimester [9,10]. The main message of our study is that maternal influenza does not induce a higher prevalence of pregnancy complications and unsuccessful delivery outcomes.…”

Section: Discussionmentioning

confidence: 51%

Pregnancy complications and delivery outcomes of pregnant women with influenza

Ács

Bánhidy

Puhó

et al. 2006

The Journal of Maternal-Fetal & Neonatal Medicine

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Section: Discussionmentioning

confidence: 51%

Pregnancy complications and delivery outcomes of pregnant women with influenza

Ács

Bánhidy

Puhó

et al. 2006

The Journal of Maternal-Fetal & Neonatal Medicine

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“…Based on observations, he speculated that if an influenza‐induced syndrome of birth defects existed, cleft lip would be among the four major congenital abnormalities most likely observed. However, several studies have disagreed that influenza infection is teratogenic (A. Czeizel, Tusnady, Domany, & Borsy, 1967; Doll, Hill, & Sakula, 1960; Walker & Mc, 1959; Widelock, Csizmas, & Klein, 1963; Wilson & Stein, 1969). Notably, different groups have reached divergent conclusions from the 1957 Asian influenza pandemic.…”

Section: Pathogens and Orofacial Cleftsmentioning

confidence: 99%

Environmental mechanisms of orofacial clefts

Garland

Reynolds

Zhou

2020

Birth Defects Research

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Orofacial clefts (OFCs) are among the most common birth defects and impart a significant burden on afflicted individuals and their families. It is increasingly understood that many nonsyndromic OFCs are a consequence of extrinsic factors, genetic susceptibilities, and interactions of the two. Therefore, understanding the environmental mechanisms of OFCs is important in the prevention of future cases. This review examines the molecular mechanisms associated with environmental factors that either protect against or increase the risk of OFCs. We focus on essential metabolic pathways, environmental signaling mechanisms, detoxification pathways, behavioral risk factors, and biological hazards that may disrupt orofacial development.

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The association between maternal influenza, drug consumption and oral clefts

Saxén

1975

Acta Odontologica Scandinavica

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The linkage between potentially teratogenic factors was studied in a material of 599 children with oral clefts and their matched controls. A method based on Yule's Q coefficient describing the degree of association between two dichotomous variables was applied. All factors studied (five groups of drugs taken by the mothers during early pregnancy, maternal influenza and fever) were significantly associated with the birth of children with clefts. The only factor whose association with clefts was explained by linkage to other factors was fever. In addition, the association between clefts and antipyretic analgesics other than salicylates could be partly explained by controlling the intake of salicylates. Although there was a strong association between influenza and consumption of salicylates, the correlation of neither of the two factors with oral clefts could be even partly explained by controlling the other. The method is considered suitable for epidemiological studies of congenital defects.

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Effects of Influenza on Pregnancy

Cited by 3 publications

References 12 publications

Pregnancy complications and delivery outcomes of pregnant women with influenza

Pregnancy complications and delivery outcomes of pregnant women with influenza

Environmental mechanisms of orofacial clefts

The association between maternal influenza, drug consumption and oral clefts

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