Effects of “in vivo” exposure to toxic sediments on juveniles of sea bass (Dicentrarchus labrax)

Domenico, Elena De; Mauceri, Angela; Giordano, Daniela; Gioffrè, Giuseppina; Natalotto, Antonino; D'Agata, Alessia; Ferrante, Margherita; Brundo, Maria Violetta; Fasulo, Salvatore

doi:10.1016/j.aquatox.2011.08.026

Cited by 38 publications

(23 citation statements)

References 44 publications

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“…Only a few studies reported a significant change in hepatic MT levels after exposure to contaminated sediment or water [87, 102, 124, 134], and in some of these the response was not observed in all fish exposed to the same contaminants [87, 102]. In contrast, MT levels exhibited a significant positive response in the gills of three different fish species [128, 129, 135], and in the muscle in two other studies [128, 132]. In laboratory toxicity tests, MT levels increased in Aphanius fasciatus , Atherinops affnis , Gobius niger , Sparus aurata and T .…”

Section: Resultsmentioning

confidence: 99%

“…Na+ / K+ ATPase (NKA) is an enzyme in the plasma membrane involved in ion transport and osmoregulation, and has been used in five studies to assess the response to metal exposure [84, 106, 135, 144, 163](S21 Table). Exposure to contaminated sediment resulted in an increase in NKA in A .…”

Section: Resultsmentioning

confidence: 99%

“…anguilla [106] but not in D . labrax [135]. Activity of NKA showed seasonal variation in fish from Brazilian estuaries likely related to ionic changes in the water rather than changes in metal contamination [84].…”

Section: Resultsmentioning

confidence: 99%

“…Single studies were identified using other osmoregulatory and respiratory markers, such as aquaporins (AQPs), Ca 2+ -ATPase, trimethylamine oxide (TMAO), urea, PaO 2 , PaCO 2 , arterial pH, K, Ca, NH 4 , Na and Cl [135, 144, 163] (S21 Table). These were not further considered for Gladstone Harbour.…”

Section: Resultsmentioning

confidence: 99%

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A protocol for identifying suitable biomarkers to assess fish health: A systematic review

2017

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BackgroundBiomarkers have been used extensively to provide the connection between external levels of contaminant exposure, internal levels of tissue contamination, and early adverse effects in organisms.ObjectivesTo present a three-step protocol for identifying suitable biomarkers to assess fish health in coastal and marine ecosystems, using Gladstone Harbour (Australia) as a case study.MethodsPrior to applying our protocol, clear working definitions for biomarkers were developed to ensure consistency with the global literature on fish health assessment. First, contaminants of concern were identified based on the presence of point and diffuse sources of pollution and available monitoring data for the ecosystem of interest. Second, suitable fish species were identified using fisheries dependent and independent data, and prioritised based on potential pathways of exposure to the contaminants of concern. Finally, a systematic and critical literature review was conducted on the use of biomarkers to assess the health of fish exposed to the contaminants of concern.Results/DiscussionWe present clear working definitions for bioaccumulation markers, biomarkers of exposure, biomarkers of effect and biomarkers of susceptibility. Based on emission and concentration information, seven metals were identified as contaminants of concern for Gladstone Harbour. Twenty out of 232 fish species were abundant enough to be potentially suitable for biomarker studies; five of these were prioritised based on potential pathways of exposure and susceptibility to metals. The literature search on biomarkers yielded 5,035 articles, of which 151met the inclusion criteria. Based on our review, the most suitable biomarkers include bioaccumulation markers, biomarkers of exposure (CYP1A, EROD, SOD, LPOX, HSP, MT, DNA strand breaks, micronuclei, apoptosis), and biomarkers of effect (histopathology, TAG:ST).ConclusionOur protocol outlines a clear pathway to identify suitable biomarkers to assess fish health in coastal and marine ecosystems, which can be applied to biomarker studies in aquatic ecosystems around the world.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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A protocol for identifying suitable biomarkers to assess fish health: A systematic review

2017

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“…As reported previously (Ausili et al, 2008;De Domenico et al, 2011Fasulo et al, 2012b), the petrochemical area of "Augusta-MelilliPriolo" was declared a "site of national interest" by the Italian Ministry of Environment (Law No. 426/98;Ministerial Decree of 10.01.2000) owing to the high level of pollution, mainly due to Hg and PAHs, and subsequent risk for human health.…”

Section: Study Areamentioning

confidence: 98%

Neurotoxicological effects on marine mussel Mytilus galloprovincialis caged at petrochemical contaminated areas (eastern Sicily, Italy): 1H NMR and immunohistochemical assays

Cappello

Maisano

Giannetto

et al. 2015

Comparative Biochemistry and Physiology Part C: Toxicology &

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Morphostructural and immunohistochemical study on the role of metallothionein in the detoxification of heavy metals in Apis mellifera L., 1758

Salvaggio

Pecoraro

Scalisi

et al. 2017

Microscopy Res & Technique

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Honey is a valuable food produced by bees from sugary substances that they gather in nature. The transformation the nectar into honey, by bees, is long and complex. Except for honey, where heavy metals are absent or are found only in traces, the bees and their products have always been considered excellent biomarkers of such contaminants. We have assumed that the absence of heavy metals in honey is due to the presence of a detoxification system in the digestive system of bees, which involves metallothioneins, proteins that have a role in the homeostatic control of essential and non-essential metals. We have placed the beehives in three different zones: industrial, urban and rural. Investigations were carried out with ICP-MS method for the detection of heavy metals in the guts of honey bees and honey. The metallothioneins have been identified by Immunohistochemical and Western-blotting analisys. The investigations have shown the presence of heavy metals only in bees guts but not in honey, while the presence of metallothionein has been highlighted only in epithelium of the honey sac, demonstrating the existence of an efficient system of detoxification of heavy metals.

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Effects of “in vivo” exposure to toxic sediments on juveniles of sea bass (Dicentrarchus labrax)

Cited by 38 publications

References 44 publications

A protocol for identifying suitable biomarkers to assess fish health: A systematic review

A protocol for identifying suitable biomarkers to assess fish health: A systematic review

Neurotoxicological effects on marine mussel Mytilus galloprovincialis caged at petrochemical contaminated areas (eastern Sicily, Italy): 1H NMR and immunohistochemical assays

Morphostructural and immunohistochemical study on the role of metallothionein in the detoxification of heavy metals in Apis mellifera L., 1758

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