“…In this Journal, the authors study, in rat models, the intracellular mechanisms involved in the excess of thyroid hormones (hyperthyroidism) in the contractility and Na+/Ca2+ Exchanger Activity in the heart muscle. 3 However, not all physiological mechanisms can be extrapolated from animals to humans because of their differences and specificities. In clinical practice, we still control heart rate with beta-blockers, and in case of contraindication, with benzothiazepine and calcium channel blocker.…”