Effects of high-intensity interval exercise versus continuous moderate-intensity exercise on postprandial glycemic control assessed by continuous glucose monitoring in obese adults

Abstract

The purpose of this study was to examine the impact of acute high-intensity interval training (HIIT) compared with continuous moderate-intensity (CMI) exercise on postprandial hyperglycemia in overweight or obese adults. Ten inactive, overweight or obese adults (41 ± 11 yrs, BMI = 36 ± 7 kg/m(2)) performed an acute bout of HIIT (10 × 1 min at approximately 90% peak heart rate (HRpeak) with 1-min recovery periods) or matched work CMI (30 min at approximately 65% HRpeak) in a randomized, counterbalanced fashion. Exercise was performed 2 h after breakfast, and glucose control was assessed by continuous glucose monitoring under standardized dietary conditions over 24 h. Postprandial glucose (PPG) responses to lunch, dinner, and the following day's breakfast were analyzed and compared with a no-exercise control day. Exercise did not affect the PPG responses to lunch, but performing both HIIT and CMI in the morning significantly reduced the PPG incremental area under the curve (AUC) following dinner when compared with control (HIIT = 110 ± 35, CMI = 125 ± 34, control = 162 ± 46 mmol/L × 2 h, p < 0.05). The PPG AUC (HIIT = 125 ± 53, CMI = 186 ± 55, control = 194 ± 96 mmol/L × 2 h) and the PPG spike (HIIT = Δ2.1 ± 0.9, CMI = Δ3.0 ± 0.9, control = Δ3.0 ± 1.5 mmol/l) following breakfast on the following day were significantly lower following HIIT compared with both CMI and control (p < 0.05). Absolute AUC and absolute glucose spikes were not different between HIIT, CMI, or control for any meal (p > 0.05 for all). We conclude that a single session of HIIT has greater and more lasting effects on reducing incremental PPG when compared with CMI.

¿Puede el ejercicio físico per se disminuir el peso corporal en sujetos con sobrepeso/obesidad?

“…Este modelo de ejercicio ha sido tradicionalmente el más utilizado en el tratamiento del sobrepeso/obesidad, y ha mostrado ser efectivo en la protección cardio-metabólica, en la elevación de la capacidad de trabajo físico 24,25 , en el incremento de la biogénesis mitocondrial 26 , expresión y traslocación de los transportadores de glucosa de tipo 4 (GLUT-4) 27,28 , aumentos en la sensibilidad a la insulina 29 , en una mejor regulación de la glicemia 30 y de los lípidos en sangre 31 . Debido a esto, algunos consideran este modelo de ejercicio como el fármaco ideal en el tratamiento de diabetes mellitus tipo 2, síndrome metabólico e hipertensión arterial 32 .…”

A single bout of exercise and postprandial hyperglycemia caused by high-fat diet

“…In one study, the glucoselowering effect of a single bout of exercise was greater with 60-min of low-intensity, continuous exercise (35% watt max) than with 30 min of high-intensity continuous exercise (70% watt max) 32) . Moreover, despite a shorter duration than continuous exercise, a single bout of highintensity interval exercise has positive effects on 24-h post-exercise blood glucose concentration and frequency of hyperglycemia [37][38][39][40][41] . With matched oxygen consumption during exercise and exercise duration, the blood glucoselowering effect is higher with high-intensity interval exercise than with continuous exercise 40) .…”

Impacto del Ejercicio en pacientes con Síndrome Post Trombótico: Una propuesta de intervención

“…Sin embargo, en los últimos años se han realizado estudios que miden la eficacia del ejercicio de alta intensidad en protocolo interválico (HIIT, Highintensity Intervalic training) en diferentes patologías y situaciones de salud. [56][57] La evidencia muestra que el entrenamiento interválico de alta intensidad genera cambios importantes y mayormente beneficiosos que cuando se compara con el entrenamiento continuo de moderada intensidad. Estas mejoras en relación con el ejercicio continuo se ven en las adaptaciones metabólicas y de la composición corporal, posicionando a este tipo de ejercicio como una estrategia prometedora en sujetos sanos y en múltiples enfermedades.…”