Effects of Halothane, Enflurane, and Isoflurane on Somatosensory Evoked Potentials during Nitrous Oxide Anesthesia

Ação do óxido nitroso no sistema nervoso central: estudo eletrofisiológico como agente único e como agente coadjuvante

“…The addition of nitrous oxide to isoflurane and desflurane produced significant changes, especially in waves N19 and P22 amplitudes, with minor onset time change of the latter. These results are in line with other authors who have shown that the association of 60% nitrous oxide significantly decreases cortical waves amplitude [28][29][30][31] . In our study, the association of nitrous oxide to isoflurane decreased even more brain waves amplitude.…”

“…A associação do óxido nitroso ao isoflurano e desflurano produziu alterações importantes, sobretudo na amplitude das ondas N19 e P22, com pequenas alterações na latência desta última. Estes resultados estão de acordo com os de outros autores mostrando que a adição de 60% de óxido nitroso causa redução significativa na amplitude das ondas corticais [28][29][30][31] . Nesse estudo a adição de óxido nitroso ao isoflurano reduziu ainda mais a amplitude das ondas cerebrais.…”

Nitrous oxide has different effects on the EEG and somatosensory evoked potentials during isoflurane anaesthesia in patients

“…S tive to volatile anaesthetic agents (1). A dose-dependent attenuation of the cortical components of median nerve SEP has been shown with isoflurane anaesthesia (2, 3).…”

Isoflurane compared with nitrous oxide anaesthesia for intraoperative monitoring of somatosensory-evoked potentials

“…6-8 Both Pathak et al 6 and Peterson et al 7 have demonstrated that 1.0 MAC isoflurane caused a reduction in the cortical amplitude, and that the addition of 60% nitrous oxide caused even more deteriorationl Since the completion of our study, Thornton et al 17 have reported their work on the comparative effects of isoflurane and nitrous oxide on evoked potentials. Their primary aim was to investigate the use of evoked potentials as a measure of depth of anaesthesia, but both the experimental design and results were remarkably similar to ours.…”