Effects of fetal involvement of inadvertent radioactive iodine therapy for the treatment of thyroid diseases during an unsuspected pregnancy

Iijima, Shigeo

doi:10.1016/j.ejogrb.2021.02.003

Cited by 7 publications

(3 citation statements)

References 24 publications

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“…Radioactive iodine can cause congenital hypothyroidism or, in extreme cases, birth defects and miscarriage. 44,45 Adequate management of conditions that may become unstable during RAI therapy, such as diabetes and cardiovascular, renal, or pulmonary disease, is essential before RAI administration. 46 Regarding ATD treatment, less than a quarter of videos (23.5%) mentioned potential adverse effects that require physician involvement.…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, for those videos that discussed RAI as a treatment option (60.0%), only a minority (36.1%) mentioned the critical consideration of pregnancy contraindications, and few (8.3%) discussed the necessity of optimizing secondary health issues before administering RAI. Radioactive iodine can cause congenital hypothyroidism or, in extreme cases, birth defects and miscarriage 44,45 . Adequate management of conditions that may become unstable during RAI therapy, such as diabetes and cardiovascular, renal, or pulmonary disease, is essential before RAI administration 46 …”

Section: Discussionmentioning

confidence: 99%

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Evaluation of YouTube As A Source For Graves' Disease Information: Is High‐Quality Guideline‐Based Information Available?

Ayo‐Ajibola,

Davis,

Therriault

et al. 2024

OTO Open

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ObjectiveTo understand the quality of informational Graves' disease (GD) videos on YouTube for treatment decision‐making quality and inclusion of American Thyroid Association (ATA) treatment guidelines.Study DesignCross‐sectional cohort.SettingInformational YouTube videos with subject matter “Graves' Disease treatment.”MethodThe top 50 videos based on our query were assessed using the DISCERN instrument. This validated algorithm discretely rates treatment‐related information from excellent (≥4.5) to very poor (<1.9). Videos were also screened for ATA guideline inclusion. Descriptive statistics were used for cohort characterization. Univariate and multivariate linear regressions characterized factors associated with DISCERN scores. Significance was set at P < .05.ResultsThe videos featured 57,513.43 views (SD = 162,579.25), 1054.70 likes (SD = 2329.77), and 168.80 comments (SD = 292.97). Most were patient education (52%) or patient experience (24%). A minority (40%) were made by thyroid specialists (endocrinologists, endocrine surgeons, or otolaryngologists). Under half did not mention all 3 treatment modalities (44%), and 54% did not mention any ATA recommendations. Overall, videos displayed poor reliability (mean = 2.26, SD = 0.67), treatment information quality (mean = 2.29, SD = 0.75), and overall video quality (mean = 2.47, SD = 1.07). Physician videos were associated with lower likes, views, and comments (P < .001) but higher DISCERN reliability (P = .015) and overall score (P = .019). Longer videos (P = .015), patient accounts (P = .013), and patient experience (P = .002) were associated with lower scores.ConclusionThe most available GD treatment content on YouTube varies significantly in the quality of medical information. This may contribute to suboptimal disease understanding, especially for patients highly engaged with online health information sources.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Evaluation of YouTube As A Source For Graves' Disease Information: Is High‐Quality Guideline‐Based Information Available?

Ayo‐Ajibola,

Davis,

Therriault

et al. 2024

OTO Open

View full text Add to dashboard Cite

show abstract

“…In women wishing to conceive, attempts at conception should therefore be delayed. A negative pregnancy test must be documented prior to RAI therapy, as there also appears to be a dose- and temporal-response relationship to the adverse effects of RAI [ 226 , 229 ]. Thus, current guidelines do not support the use of RAI in preconception states, and thionamides may be a more suitable option ( Table 3 ) [ 226 ].…”

Section: Approach To Management Of Thyroid-related Reproductive Dysfu...mentioning

confidence: 99%

The Thyroid Hormone Axis and Female Reproduction

Brown

Obeng-Gyasi

Hall

et al. 2023

IJMS

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Thyroid function affects multiple sites of the female hypothalamic-pituitary gonadal (HPG) axis. Disruption of thyroid function has been linked to reproductive dysfunction in women and is associated with menstrual irregularity, infertility, poor pregnancy outcomes, and gynecological conditions such as premature ovarian insufficiency and polycystic ovarian syndrome. Thus, the complex molecular interplay between hormones involved in thyroid and reproductive functions is further compounded by the association of certain common autoimmune states with disorders of the thyroid and the HPG axes. Furthermore, in prepartum and intrapartum states, even relatively minor disruptions have been shown to adversely impact maternal and fetal outcomes, with some differences of opinion in the management of these conditions. In this review, we provide readers with a foundational understanding of the physiology and pathophysiology of thyroid hormone interactions with the female HPG axis. We also share clinical insights into the management of thyroid dysfunction in reproductive-aged women.

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Thyroid Nodule and Carcinoma in Pregnancy

Parvathi,

Anantharaju

2023

Thyroid Disease in Pregnancy - A Guide to Clinical Management

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Effects of fetal involvement of inadvertent radioactive iodine therapy for the treatment of thyroid diseases during an unsuspected pregnancy

Cited by 7 publications

References 24 publications

Evaluation of YouTube As A Source For Graves' Disease Information: Is High‐Quality Guideline‐Based Information Available?

Evaluation of YouTube As A Source For Graves' Disease Information: Is High‐Quality Guideline‐Based Information Available?

The Thyroid Hormone Axis and Female Reproduction

Thyroid Nodule and Carcinoma in Pregnancy

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