Effects of endurance training on serum lipids

Fikenzer, Kati; Fikenzer, Sven; Laufs, Ulrich; Werner, Christian

doi:10.1016/j.vph.2017.11.005

Cited by 50 publications

(36 citation statements)

References 74 publications

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“…Regular exercise has also been shown to improve the lipid pro le in individuals with T2DM (35,36). In our investigation, only the HIIT group observed signi cant changes in the circulating levels of LDL-C and total cholesterol compared to controls, whereas no changes were observed for the MCT group after 1-year of intervention.…”

Section: Resultscontrasting

confidence: 43%

Impact of Combined Training with Different Exercise Intensities on Inflammatory and Lipid Markers in Type 2 Diabetes: A Secondary Analysis from a 1-Year Randomized Controlled Trial

Magalhães

Santos

Correia

et al. 2020

Preprint

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Background: Exercise is a well-accepted strategy to improve lipid and inflammatory profile in individuals with type 2 diabetes (T2DM). However, the exercise intensity having the most benefits on lipids and inflammatory markers in patients with T2DM remains unclear. We aimed to analyse the impact of a 1-year combined high-intensity interval training (HIIT) with resistance training (RT), and a moderate continuous training (MCT) with RT on inflammatory and lipid profile in individuals with T2DM.Methods: Individuals with T2DM (n=80, aged 59 years) performed a 1-year randomized controlled trial and were randomized into three groups (control, n= 27; HIIT with RT, n=25; MCT with RT, n=28). Exercise sessions were supervised with a frequency of 3 days per week. Inflammatory and lipid profiles were measured at baseline and at 1-year follow-up. Changes in inflammatory and lipid markers were assessed using generalized estimating equations. Results: After adjusting for sex, age and baseline moderate-to-vigorous physical activity (MVPA), circulating levels of Interleukin-6 (IL-6) decreased for both the MCT with RT (β=-0.70, p=0.034) and HIIT with RT (β=-0.62, p=0.049) groups, whereas, only the HIIT with RT group improved total cholesterol (β=-0.03, p=0.045) and LDL-C (β=-0.03, p=0.034), when compared to control. No effect was observed for C-reactive protein (CRP), cortisol, tumour necrosis factor-α (TNF-α), soluble form of the haptoglobin-hemoglobin receptor CD163 (sCD163), triglycerides and HDL-C in both groups (p>0.05).Conclusions: Favorable adaptations on IL-6 were observed in both the HIIT and MCT combined with RT groups following a long-term 1-year exercise intervention in individuals with T2DM. However, the HIIT with RT group improved to a greater extent the values of total cholesterol and LDL-C, when compared to the MCT with RT group. Therefore, in order to encourage exercise participation and improve inflammatory profile, either exercise protocols may be prescribed, however, HIIT with RT may have further benefits on the lipid profile.Trial registration: clinicaltrials.gov ID:NCT03144505

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Section: Resultscontrasting

confidence: 43%

Impact of Combined Training with Different Exercise Intensities on Inflammatory and Lipid Markers in Type 2 Diabetes: A Secondary Analysis from a 1-Year Randomized Controlled Trial

Magalhães

Santos

Correia

et al. 2020

Preprint

View full text Add to dashboard Cite

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“…En individuos con obesidad, un meta-análisis Cochrane que incluyó 43 estudios con 3.476 participantes encontró que una intervención de actividad física que duró al menos 12 semanas indujo una disminución media en la TG en ayunas de 18 mg/dL, independiente de las modificaciones nutricionales (36) . Otro meta-análisis del entrenamiento de resistencia regular entre los hombres, que incluyó 49 estudios y 2.990 participantes, encontró una disminución media de TG de 9 % y una correlación positiva entre la disminución de TG y la intensidad del ejercicio (37) .…”

Section: Impacto Del Ejercicio Sobre Los Triglicéridos Plasmáticosunclassified

Impacto del ejercicio sobre el metabolismo de los lípidos y la dislipidemia

Scher-Nemirovsky¹,

Ruiz-Manco²,

Mendivil³

2019

Rev. Nutr. Clin. Metab.

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The chronic practice of exercise induces a series of cellular and organismal adaptations that modify the way the human body metabolizes all macronutrients, including lipids. Endurance exercise and resistance exercise elicit different responses that result in differential effects on lipid and lipoprotein metabolism. These effects are quantitatively and qualitatively different and mediated by distinct signaling pathways. In this review, we summarize relevant evidence on the impact of exercise on lipid and lipoprotein metabolism, and finalize with some practical recommendations on exercise practice for patients with dyslipidemia in the primary care setting.

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“…Körperliche Aktivität kann das HDL-Cholesterin erhöhen, ein Effekt auf die Triglyzeride ist fast immer zu beobachten. Eine aktuelle Metaanalyse [12] mit Ausdauer-Interventionsstudien (Intensität: 65-80 % VO 2 max, Umfang 40-50 min pro Trainingseinheit, Frequenz 3-4-mal pro Woche, 26-40 Wochen Interventionsdauer) bestätigt dies mit einer Verringerung der Triglyzeride um 8 % (p = 0,0004) und einem Ansteigen des HDL-Cholesterins um 4 % (p = 0,0061). Der Effekt auf das LDL-Cholesterin ist gering [13], jedoch werden Subfraktionen der LDL-Partikel, wie das besonders atherogen wirkende sdLDL-Partikel ("small-dense" LDL-Partikel), durch körperliche Aktivität vermindert und die LDL-Partikelgröße erhöht, worin ein antiatherogener Effekt bestehen soll [14].…”

Section: Lipideunclassified