Effects of Electromagnetic Field Produced by Mobile Phones on the Oxidant and Antioxidant Status of Rats

Elhag, M. A.; Nabil, Ghada M.; Attia, Atef

doi:10.3923/pjbs.2007.4271.4274

Cited by 15 publications

(2 citation statements)

References 14 publications

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“…No changes in reactive oxygen species formation after 10 min and 30 min of exposure to 900 MHz RF were detected in L929 murine fibrosarcoma cells, whilst several studies on rats reported an increase in oxidative stress (an increase in malondialdehyde as an index of lipid peroxidation) and a decrease in superoxide dismutase, catalase and glutathione peroxidase activity. 28,29,30,31,32 Yurekli et al 33 also reported an increase in oxidative stress and an increase in superoxide dismutase activity, whilst Balci et al 34 reported an increase in oxidative stress and catalase activity in EMF-irradiated rat corneal tissue and no significant changes in rat lens tissue. Our results did not demonstrate any statistically significant differences, even though all the averages of the irradiated samples were less than the controls (H 2 O 2 < 13%, superoxide < 5% and NOS < 4%).…”

Section: Discussionmentioning

confidence: 99%

Effects of non-thermal mobile phone radiation on breast adenocarcinoma cells

et al. 2011

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Mobile phone usage currently exceeds landline communication in Africa. The extent of this usage has raised concerns about the long-term health effects of the ongoing use of mobile phones. To assess the physiological effects of radiation from mobile phones in vitro, MCF-7 breast adenocarcinoma cells were exposed to 2W/kg non-thermal 900-MHz mobile phone radiation. The effects investigated were those on metabolic activity, cell morphology, cell cycle progression, phosphatidylserine (PS) externalisation and the generation of reactive oxygen species and nitrogen species. Statistically insignificant increases in mitochondrial dehydrogenase activity were observed in irradiated cells when compared to controls. Fluorescent detection of F-actin demonstrated an increase in F-actin stress fibre formation in irradiated MCF-7 cells. Cell cycle progression revealed no statistically significant variation. A small increase in early and late apoptotic events in irradiated MCF-7 cells was observed. No statistically significant changes were observed in reactive oxygen and reactive nitrogen species generation. In addition, quantitative and qualitative analyses of cell cycle activity and nuclear and cytosolic changes, respectively, revealed no significant changes. In conclusion, exposure to 1 h of 900-MHz irradiation induced an increase in PS externalisation and an increase in the formation of F-actin stress fibres in MCF-7 cells. Data obtained from this study, and their correlation with other studies, provides intriguing links between radio frequency radiation and cellular events and warrant further investigation.

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Section: Discussionmentioning

confidence: 99%

Effects of non-thermal mobile phone radiation on breast adenocarcinoma cells

et al. 2011

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“…The intracellular enzymatic defense against free radicals involves superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (Guler et al, 2007). There are several reports which indicate that the exposure to EMF reduces antioxidant enzyme activities in the rat tissues (Elhag et al, 2007; Ozguner et al, 2005b).…”

Section: Introductionmentioning

confidence: 99%

The effects of exposure to electromagnetic field on rat myocardium

et al. 2012

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Exposure to electromagnetic fields (EMFs) causes increased adverse effects on biological systems. The aim of this study was to investigate the effects of EMF on heart tissue by biochemical and histomorphological evaluations in EMF-exposed adult rats. In this study, 28 male Wistar rats weighing 200-250 g were used. The rats were divided into two groups: sham group (n = 14) and EMF group (n = 14). Rats in sham group were exposed to same conditions as the EMF group except the exposure to EMF. Rats in EMF group were exposed to a 50-Hz EMF of 3 mT for 4 h/day and 7 days/week for 2 months. After 2 months of exposure, rats were killed; the hearts were excised and evaluated. Determination of oxidative stress parameters was performed spectrophotometrically. To detect apoptotic cells, terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) staining and caspase-3 immunohistochemistry were performed. In EMF-exposed group, levels of lipid peroxidation significantly increased and activities of superoxide dismutase and glutathione peroxidase decreased compared with sham group. The number of TUNEL-positive cells and caspase-3 immunoreactivity increased in EMF-exposed rats compared with sham. Under electron microscopy, there were mitochondrial degeneration, reduction in myofibrils, dilated sarcoplasmic reticulum and perinuclear vacuolization in EMF-exposed rats. In conclusion, the results show that the exposure to EMF causes oxidative stress, apoptosis and morphologic damage in myocardium of adult rats. The results of our study indicate that EMF-related changes in rat myocardium could be the result of increased oxidative stress. Further studies are needed to demonstrate whether the exposure to EMF can induce adverse effects on myocardium.

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Mobile Telephony EMFs Effects on Insect Ovarian Cells. The Necessity for Real Exposures Bioactivity Assessment. The Key Role of Polarization, and the “Ion Forced-Oscillation Mechanism”

Panagopoulos

2017

Microwave Effects on DNA and Proteins

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Effects of Electromagnetic Field Produced by Mobile Phones on the Oxidant and Antioxidant Status of Rats

Cited by 15 publications

References 14 publications

Effects of non-thermal mobile phone radiation on breast adenocarcinoma cells

Effects of non-thermal mobile phone radiation on breast adenocarcinoma cells

The effects of exposure to electromagnetic field on rat myocardium

Mobile Telephony EMFs Effects on Insect Ovarian Cells. The Necessity for Real Exposures Bioactivity Assessment. The Key Role of Polarization, and the “Ion Forced-Oscillation Mechanism”

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