Effects of diquat on the gastrointestinal tract of rats

Crabtree, Helen C.; Lock, Edward A.; Rose, Michael S.

doi:10.1016/s0041-008x(77)80012-4

Cited by 28 publications

(8 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The greenish stool color is due to the bacterial reduction of diquat in the intestine. Due to the acute depletion of water, hemoconcentration may also be noted (Verbetskii and Pushka, 1968;Clark and Hurst, 1970;Crabtree, 1977;Cobb and Grimshaw, 1979). The next phase of diquat oral toxicity is the development of a paralytic illeus.…”

Section: Oral Toxicitymentioning

confidence: 99%

“…Diquat appears to have an effect on the water distribution in the body suggesting a direct action on the stomach and intestinal mucosa. Depending upon the dose, the test animals may demonstrate lethargy, collapse, coma and death (Crabtree, 1977;Cobb and Grimshaw, 1979;Schmidt, 2000).…”

Section: Oral Toxicitymentioning

confidence: 99%

“…The intestinal submucosal epithelium demonstrated infiltration of lymphocytes and polymorphonuclear and mononuclear cells. Death in the test animals was attributed to destruction of the intestinal epithelium and kidney damage (Crabtree, 1977;Cobb and Grimshaw, 1979).…”

Section: Oral Toxicitymentioning

confidence: 99%

“…These incidents have involved mostly suicidal and some accidental diquat ingestion cases. Signs and symptoms associated with skin and inhalation overexposure to diquat concentrate or spray mist are primarily displayed by manifestation of tissue irritation (Schonborn, 1971;Crabtree, 1977;Vanholder, 1981;Van Den Heede, 1982;Hantson, 2000;Schmidt, 2000).…”

Section: Human Case Reports and Studiesmentioning

confidence: 99%

“…Based on the weight of the evidence from the diquat toxicology investigations, occupational use and clinical findings, the chemical is not considered to be a neurotoxin. No neurological effects have been reported from incidental ingesting of spray dilution or swallowing of diquat treated water while swimming or in situations where the treated water was used as a drinking water source (Swan, 1969;Schonborn, 1971;Crabtree, 1977;Vanholder, 1981;Van Den Heede, 1982;Wojeck, 1983;Hantson, 2000;Schmidt, 2000).…”

Section: Human Neurological Case Reportsmentioning

confidence: 99%

See 4 more Smart Citations

Effects of Aquatic Herbicides and Housing Density on Abundance of Pond-Breeding Frogs

Picone

2015

Northeastern Naturalist

View full text Add to dashboard Cite

Section: Oral Toxicitymentioning

confidence: 99%

Section: Oral Toxicitymentioning

confidence: 99%

Section: Oral Toxicitymentioning

confidence: 99%

Section: Human Case Reports and Studiesmentioning

confidence: 99%

Section: Human Neurological Case Reportsmentioning

confidence: 99%

See 3 more Smart Citations

Effects of Aquatic Herbicides and Housing Density on Abundance of Pond-Breeding Frogs

Picone

2015

Northeastern Naturalist

View full text Add to dashboard Cite

Alkylpyridines and Miscellaneous Organic Nitrogen Compounds

Trochimowicz¹,

Kennedy²,

Krivanek³

2001

Patty's Toxicology

View full text Add to dashboard Cite

This chapter covers additional aliphatic and aromatic compounds that contain one or more nitrogen atoms in their structures and follows those discussed in Chapter 59. Pyridine and its many modified structures are described because they serve as a backbone for many industrial compounds. Several pesticides and herbicides, as well as their precursors, are included: the pyridinethiones, the substituted uracils herbicides: bromacil, lenacil, terbacil; the quaternary herbicides: paraquat, diquat, and difenzoquat; the s ‐triazines: atrazine and propazine and other triazine herbicides, such as ametryn, prometryne, and simazine. Simple nitrogen compounds such as azides, nitrosamines, and hydrazines are described because of important toxicological effects they can produce. Finally, two important industrial solvents, dimethylacetamide and dimethylformamide are included because they have a long history of use and have been well studied in the occupational environment.

show abstract

Alkylpyridines and Miscellaneous Organic Nitrogen Compounds

Trochimowicz¹,

Kennedy²,

Krivanek³

2012

Patty's Toxicology

View full text Add to dashboard Cite

This chapter covers additional aliphatic and aromatic compounds that contain one or more nitrogen atoms in their structures and follows those discussed in Chapter 59. Pyridine and its many modified structures are described because they serve as a backbone for many industrial compounds. Several pesticides and herbicides, as well as their precursors, are included: the pyridinethiones; the substituted uracil herbicides—bromacil, lenacil, and terbacil; the quaternary herbicides–paraquat, diquat, and difenzoquat; the s ‐triazines—atrazine and propazine; and other triazine herbicides, such as ametryn, prometryne, and simazine. Simple nitrogen compounds such as azides, nitrosamines, and hydrazines are described because of important toxicological effects they can produce. Finally, two important industrial solvents, dimethylacetamide and dimethylformamide, are included because they have a long history of use and have been well studied in the occupational environment. Other than the pyridine series of chemicals and the nitroso compounds, most of the chemicals reviewed here include significant new information since the last chapter review.

show abstract

Effects of diquat on the gastrointestinal tract of rats

Cited by 28 publications

References 11 publications

Effects of Aquatic Herbicides and Housing Density on Abundance of Pond-Breeding Frogs

Effects of Aquatic Herbicides and Housing Density on Abundance of Pond-Breeding Frogs

Alkylpyridines and Miscellaneous Organic Nitrogen Compounds

Alkylpyridines and Miscellaneous Organic Nitrogen Compounds

Contact Info

Product

Resources

About