Effects of different regimens of iron prophylaxis on maternal iron status and pregnancy outcome: a randomized control trial

Parisi, Francesca; Berti, Cristiana; Mandò, Chiara; Martinelli, Anna; Mazzali, Cristina; Cetin, Irene

doi:10.1080/14767058.2016.1224841

Cited by 50 publications

(56 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The distinguishing features of Fisiogen Ferro Forte® make it possible to use it in all those patients, who are intolerant to oral treatment or who present a malabsorption of conventional oral iron preparations whose bioavailability is excessively limited, thus guaranteeing therapeutic adherence to treatment with oral iron and the consequent recovery of blood parameters [7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Budget Impact Analysis of Oral Fisiogen Ferro Forte® versus Intravenous Iron for the Management of Iron Deficiency in Chronic Kidney Disease in Spain

Darbà

Ascanio

2018

Clin Drug Investig

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Budget Impact Analysis of Oral Fisiogen Ferro Forte® versus Intravenous Iron for the Management of Iron Deficiency in Chronic Kidney Disease in Spain

Darbà

Ascanio

2018

Clin Drug Investig

View full text Add to dashboard Cite

show abstract

“…However, Olmos et al . showed that glycemic control in GDM patients was not enough to reduce macrosomia, and that iron supplementation was positively correlated with birthweight. We carried out multivariate regression analysis, showing that a high level of plasma ferritin (>70 ng/mL) was an independent risk factor for macrosomia, which could not be adjusted by PG and pre‐pregnancy BMI (Table ).…”

Section: Discussionmentioning

confidence: 94%

Correlation between plasma ferritin level and gestational diabetes mellitus and its impact on fetal macrosomia

Wang

Fan

Yang

et al. 2018

J of Diabetes Invest

View full text Add to dashboard Cite

Aims/IntroductionTo explore the relationship between plasma iron levels and gestational diabetes mellitus, as well as its impact on macrosomia.Materials and MethodsWe retrospectively compared ferritin level and other characteristics between pregnant women with gestational diabetes mellitus (GDM) and pregnant women without GDM. The correlation between the levels of plasma ferritin, glucose and hemoglobin was explored. Meanwhile, we assessed the risk factors of macrosomia. Furthermore, we explored the relationship between ferritin level and the incidence of macrosomia.ResultsA total of 793 pregnant women were enrolled in the present study, of which 92 pregnant women had GDM and 701 pregnant women were healthy. Meanwhile, 51 pregnant women gave birth to infants with macrosomia and another 742 women had normal infants. Compared with non‐GDM women, pregnant women with GDM were older, with higher pre‐pregnancy body mass index, plasma ferritin, fasting plasma glucose, 1‐h postprandial glucose, 2‐h plasma glucose and hemoglobin. In addition, our results showed a significant positive correlation between the levels of ferritin and fasting plasma glucose when ferritin levels were >70 ng/mL. Our results also showed that pre‐pregnancy overweight or obesity, a high concentration of ferritin, as well as abnormal levels of fasting plasma glucose, 1‐h plasma glucose and 2 h plasma glucose were risk factors for macrosomia. Furthermore, as the level of ferritin increased, so did the incidence of macrosomia.ConclusionsThe current study provides evidence that pregnant women with high levels of ferritin might be prone to GDM. In addition, a high level of ferritin might be an independent risk factor for macrosomia. Therefore, the negative effect of iron supplementation in non‐anemic pregnant women might be noteworthy.

show abstract

“…Parisi et al [28] Numerically, drop-outs were higher in control (n = 6), SF and FF14 (n = 5 each) than FF28 (n = 2).…”

Section: Clinical Evidence In Pregnant Femalesmentioning

confidence: 90%

Liposomal Iron for Iron Deficiency Anemia in Women of Reproductive Age: Review of Current Evidence

Biniwale¹,

Pal²,

Sundari³

et al. 2018

OJOG

View full text Add to dashboard Cite

Iron deficiency anemia is the most frequent nutritional deficiency disorder. Conventionally administered oral iron is associated with gastrointestinal intolerance that affects the outcomes and compliance. Liposomal iron is associated with increased absorption without causing significant adverse effects. In this review, we have discussed the technology of liposomal iron preparation, mechanisms of its absorption and clinical evidence on its utility in iron deficiency states in pregnant and non-pregnant women. Based on the available evidence, we compared liposomal iron to conventional oral iron. Encapsulation of micronized iron in liposomes is associated with lesser exposure to gastric contents, lesser interaction with food contents, no exposure to different digestive juices, targeted delivery of iron and allows lower doses to be administered in lieu of direct absorption without need for protein carriers. The available evidence suggests that liposomal iron significantly increases hemoglobin, ferritin levels in pregnant women as well as in women with iron deficiency.

show abstract

Effects of different regimens of iron prophylaxis on maternal iron status and pregnancy outcome: a randomized control trial

Abstract: Our data show the effectiveness of 28 mg and 14 mg LI on maternal anemia prevention, as previously reported with FI 40 mg. LI has similar effects of higher doses of ferrous iron on maternal hematological parameters, thus allowing to reduce iron doses and side effects.

Cited by 50 publications

References 29 publications

Budget Impact Analysis of Oral Fisiogen Ferro Forte® versus Intravenous Iron for the Management of Iron Deficiency in Chronic Kidney Disease in Spain

Budget Impact Analysis of Oral Fisiogen Ferro Forte® versus Intravenous Iron for the Management of Iron Deficiency in Chronic Kidney Disease in Spain

Correlation between plasma ferritin level and gestational diabetes mellitus and its impact on fetal macrosomia

Liposomal Iron for Iron Deficiency Anemia in Women of Reproductive Age: Review of Current Evidence

Contact Info

Product

Resources

About