Effects of dietary selenium on differentiation, morphology and functions of spermatozoa of the house rat, Ratuus rattus L.

Kaur, Rajinder; Parshad, V. R.

doi:10.1016/0027-5107(94)90039-6

Cited by 23 publications

(7 citation statements)

References 21 publications

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“…However, there are several reports in the literature associating high seminal plasma selenium with impaired sperm motility in humans (Bleau et al, 1984;Takasaki et al, 1987;Hansen and Deguchi, 1996). Supplementation of rat diets with levels of selenium approximately 4 times higher than was used in the present study has also been reported to cause a decrease in sperm motility (Kaur and Parshad, 1994).…”

Section: Discussionsupporting

confidence: 49%

The Effects of Dietary Selenium on the Immune System in Healthy Men

Hawkes

Kelley

Taylor

2001

BTER

170

110

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Eleven men were fed foods naturally high or low in selenium for 120 d. Selenium intake was stabilized at 47 microg/d for 21 d, then changed to either 13 or 297 microg/d for 99 d, leading to significantly different blood selenium and glutathione peroxidase concentrations. Serum immunoglobulins, complement components, and primary antibody responses to influenza vaccine were unchanged. Antibody titers against diphtheria vaccine were 2.5-fold greater after reinoculation in the high selenium group. White blood cell counts decreased in the high-selenium group and increased in the low-selenium group, resulting primarily from changes in granulocytes. Apparent increases in cytotoxic T-lymphocytes and activated T-cells in the high-selenium group only approached statistical significance. Lymphocyte counts increased on d 45 in the high-selenium group. In vitro proliferation of peripheral lymphocytes in autologous serum in response to pokeweed mitogen was stimulated in the high-selenium group by d 45 and remained elevated throughout the study, whereas proliferation in the low selenium group did not increase until d 100. This study indicates that the immune-enhancing properties of selenium in humans are the result, at least in part, of improved activation and proliferation of B-lymphocytes and perhaps enhanced T-cell function.

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Section: Discussionsupporting

confidence: 49%

The Effects of Dietary Selenium on the Immune System in Healthy Men

Hawkes

Kelley

Taylor

2001

BTER

170

110

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“…The homogenate was diluted with sperm count solution. Sperm numbers per milliliter were determined using a hemocytometer [Rao et al, 1993;Flores et al, 1994;Kaur and Parshad, 1994]. To determine normal and abnormal sperm morphology, two hematoxylin-eosin stained slides were prepared for each rat.…”

Section: Examination Of Epididymal Sperm Counts and Morphologymentioning

confidence: 99%

Whole body exposure of rats to microwaves emitted from a cell phone does not affect the testes

Daşdağ¹,

Akdağ²,

Aksen³

et al. 2003

Bioelectromagnetics

150

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The objective of this study was to investigate the effects of radiofrequency radiation emitted from cellular phones on the lipid composition, malondialdehyde concentration, p53 immune reactivity, sperm count, morphology, histological structure of testes, and on rectal temperature of rats exposed to microwave radiation emitted from cellular phones. Sixteen Spraque-Dawley rats were separated into two groups of eight, sham exposed (control) and experimental. The rats were confined in plexiglas cages specially designed for this study, and cellular phones were placed 0.5 cm under the cages. For the experimental group, cellular phones were activated 20 min per day (7 days a week) for 1 month. For the control group, the cellular phones were placed beneath the cages for 20 min a day, but the phones were turned off. Rectal temperatures were measured weekly. For 250 mW radiated power, the whole body average SAR (rms) is 0.52 W/kg and 1 g averaged peak SAR (rms) is 3.13 W/kg. The Mann-Whitney U-test was used for statistical comparisons of groups. No statistically significant alteration in any of the endpoints was noted. This study found no evidence suggesting an adverse effect of cell phone exposure on measures of testicular function or structure.

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“…In testes, Se, an essential trace element, is of fundamental importance, as any deficiency in its nutritional levels reduces testicular mass and morphology, besides causing other flagellar defects in sperms [5]. Even the supranutritional levels of Se can cause severe abnormalities in sperms [6] due to increased oxidative stress. Deficiency in Se causes oxidative stress in testes due to the diminished antioxidant property of this element as part of GSH-Px [7].…”

Section: Introductionmentioning

confidence: 99%