Effects of Dietary Quercetin on Growth Performance, Blood Biochemical Parameter, Immunoglobulin and Blood Antioxidant Activity in Broiler Chicks

Kim, Dong-Wook; Hong, Eui-Chul; Kim, Ji-Hyuk; Bang, Han-Tae; Choi, Ji-Young; Ji, Sang-Yoon; Lee, Wang-Shik; Kim, Sang-Ho

doi:10.5536/kjps.2014.42.1.33

Cited by 13 publications

(14 citation statements)

References 31 publications

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“…Flavonoids such as quercetin (bioactive compound of POLM), which is a flavone, enhance the secretion of insulin-like growth factor-1, which results due to the increased concentration of growth hormone and stimulation of hepatic growth hormone receptor [ 65 ]. Thus, the supplementation of quercetin improved production performance in broilers [ 66 ]. In the present study, broilers fed on the diet Po8 showed increased growth performance compared to the NC group; these outcomes are parallel to Aroche et al [ 67 ] and Zhou et al [ 68 ] where they reported that supplementation of PFAs mix powder and baicalein flavonoids resulted in increased BWG and improved FCR in broiler chickens.…”

Section: Discussionmentioning

confidence: 99%

Comparative Efficacy of Selected Phytobiotics with Halquinol and Tetracycline on Gut Morphology, Ileal Digestibility, Cecal Microbiota Composition and Growth Performance in Broiler Chickens

Basit

Kadir

Loh

et al. 2020

Animals

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The current experiment was designed to estimate the comparative efficacy of selected phytobiotics Persicaria odorata leaf meal (POLM) and Piper betle leaf meal (PBLM) with halquinol, and tetracycline in broiler chickens. The 150-day-old broiler chickens were randomly assigned to five dietary groups. The dietary supplementation groups were the basal diet (BD), which served as the negative control (NC), and BD + 0.2 g/kg tetracycline, which served as the positive control (PC); BD + 0.03 g/kg halquinol (HAL), BD + 8 g/kg POLM (Po8), and BD + 4 g/kg PBLM (Pb4) were the treatment groups. Growth performance, gut morphology, ileal digestibility, and cecal microbiota composition were measured. On day 21, the body weight gain (BWG) was enhanced (p < 0.05) in the broiler chickens fed on phytobiotics (Po8 and Pb4) relative to the NC group, however, on day 42 and in terms of overall growth performance, BWG was enhanced (p < 0.05 in diets (Po8, Pb4, HAL and PC) in comparison with the NC group. Conversely, feed conversion ratio (FCR) was recorded reduced (p < 0.05) in Pb4, Po8, HAL, and PC group in comparison with the NC group. Supplementation of phytobiotics (Po8 and Pb4), HAL and PC, positively improved the gut morphology compared to the NC group. Furthermore, the maximum (p < 0.05) villus height (VH) in duodenum and jejunum was observed in broilers fed on diet Pb4. Supplementation of phytobiotics, HAL and PC, improved (p < 0.05) the digestibility of dry matter (DM) (except for HAL), organic matter (OM), crude protein (CP), ether extract (EE), and ash compared to the NC group. Dietary supplementation of phytobiotics (Po8 and Pb4), HAL and PC, significantly reduced the E. coli, Salmonella, and Staphylococcus aureus (except for HAL) counts compared to the NC group. However, supplementation of Pb4 resulted in significantly decreased total anaerobic bacteria and Clostridium spp. counts compared to the NC group. In addition, supplementation of phytobiotics significantly increased the Lactobacillus count compared to HAL, PC, and NC groups. In conclusion, dietary supplementation of phytobiotics improved the gut morphology, positively modulated and maintained the dynamics of cecal microbiota with enhanced nutrient digestibility, thus, increased the growth performance. Based on current results, phytobiotics could be used as an alternative to AGPs for sustainable broiler chicken production.

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Section: Discussionmentioning

confidence: 99%

Comparative Efficacy of Selected Phytobiotics with Halquinol and Tetracycline on Gut Morphology, Ileal Digestibility, Cecal Microbiota Composition and Growth Performance in Broiler Chickens

Basit

Kadir

Loh

et al. 2020

Animals

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“…Quercetin is a flavone that should improve growth in birds by upregulating growth hormone, triggering the hepatic growth hormone receptor; this stimulus increases the concentration of insulin-like growth factor-1 [ 39 ]. Kim et al [ 40 ] reported increased broiler growth by supplementing quercetin in broilers. Quercetin can limit the effects of oxidative stress [ 41 ] and pro-inflammatory cytokines such as TNF-α, interleukin, and cyclooxygenase-2 [ 42 ], thus modulating the gut environment to better utilise the nutrients, improving the growth in birds.…”

Section: Discussionmentioning

confidence: 99%

Effects of Inclusion of Different Doses of Persicaria odorata Leaf Meal (POLM) in Broiler Chicken Feed on Biochemical and Haematological Blood Indicators and Liver Histomorphological Changes

Basit

Kadir

Loh

et al. 2020

Animals

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This research was conducted to estimate the effects of Persicaria odorata leaf meal (POLM) on haematological indices, serum biochemical attributes, and internal organs parameters, including histomorphological features of the liver, in broiler chickens. A total of 120 one-day-old male broiler chicks (Cobb-500) were randomly allocated into four experimental groups. The dietary treatments were basal diet (BD), which served as the control (C), along with BD + 2 g/kg POLM (Po2), BD + 4 g/kg POLM (Po4), BD + 8 g/kg POLM (Po8), which were the supplemented groups. The body weight gain (BWG) showed a linear increase and feed conversion ratio (FCR) showed a linear decrease with increasing POLM dosage at day 42 (p ˂ 0.05) and for the overall growth performance period (p ˂ 0.01). On day 21 and day 42, the values of red blood cells (RBCs), white blood cells (WBCs), haemoglobin (Hb), and packed cell volume (PCV) showed linear increases (p ˂0.05) as the dosage of POLM increased in the diet. On day 21, dietary supplementation of POLM linearly decreased (p ˂ 0.05) the serum activity of alkaline phosphatase (ALP), aspartate aminotransaminase (AST), alanine aminotransaminase (ALT), and serum levels of urea and creatinine. On the other hand, serum levels of total protein (TP), albumin, and globulin showed a linear increase (p ˂ 0.05) as the POLM dosage increased. On day 42, the serum activity of AST and ALT and serum levels of glucose, cholesterol, triglycerides, urea, and creatinine showed linear decreases (p ˂ 0.05) with increased levels of POLM in the diet. However, POLM supplementation linearly increased (p ˂ 0.05) the serum levels of TP and globulin. Dietary inclusion of POLM did not influence the organ parameters and showed no adverse effects on the liver histomorphology. In conclusion, supplementation of POLM increased the growth performance, improving haematological indices and serum biochemistry profiles of broiler chickens without any deleterious effects on the liver histomorphology. The results of the present study provide evidence that POLM can be safely used at a dose rate of 8 g/kg of feed as an alternative to conventional antimicrobial growth promoters (AGPs).

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“…In broilers, the supplementation of 0.2 g/kg of quercetin promoted growth and WG (Kim et al, ). Tilapia, Oreochromis niloticus fed diets containing 0.2–0.8 g/kg (J. Li, Liu, et al, ) or 0.2–1.6 g/kg (Zhai & Liu, 2013) of quercetin showed significantly higher WG and lower FCR than the control fish.…”

Section: Discussionmentioning

confidence: 99%

“…In broilers, the supplementation of 0.2 g/kg of quercetin promoted growth and WG (Kim et al, 2015). Tilapia, Note: Values in the same row with different letters indicate significant differences (p < .05) (n = 3).…”

Section: Discussionmentioning

confidence: 99%

“…Quercetin has been reported to have the functions of lowering blood pressure (Yamamoto & Oue, 2006) and antioxidation and antitumor properties (Boots, Haenen, & Bast, 2008). Studies demonstrated that dietary quercetin improved the growth performance and the immunity of chicken (Kim et al, 2015) and promoted sensory scores such as color, texture, and overall acceptability of goat loin (Sung et al, 2010). In aquatic animals, quercetin was reported to improve the growth and immunity and reduce the lipid content in tilapia (Oreochromis spp.)…”

Section: Introductionmentioning

confidence: 99%

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Dietary quercetin improved the growth, antioxidation, and flesh quality of grass carp (Ctenopharyngodon idella)

Yang

et al. 2019

J World Aquaculture Soc

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To investigate the effects of dietary quercetin on growth, antioxidation, and flesh quality of grass carp, Ctenopharyngodon idella, six diets were prepared with quercetin inclusion rates of 0 (control diet), 0.1, 0.2, 0.4, 0.6, and 0.8 g/kg. Grass carp with a body weight of 13.3 ± 0.1 g were fed with one of the six diets for 60 days. The weight gain (WG) showed a quadratic relationship with dietary quercetin levels; the supplementation of 0.4 g/kg quercetin significantly improved WG (+4.73%) and decreased feed conversion ratio (−0.06) (p < .05) when compared to those of the control group. The intestinal fat ratio was reduced by the addition of 0.2 or 0.4 g/kg of quercetin (p < .05), and serum activities of alkaline phosphatase and superoxide dismutase were increased by the addition of 0.4 and 0.6 g/kg of quercetin (p < .05). The inclusion of 0.2–0.6 g/kg of quercetin increased the contents of delicious amino acids and decreased the cooking loss of flesh (p < .05). Flesh collagen content was increased by the addition of 0.4–0.8 g/kg of quercetin (p < .05). In conclusion, dietary quercetin could improve the growth and enhance the antioxidation and flesh quality of grass carp, with the recommended supplemental level of quercetin was 0.37 g/kg.

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Effects of Dietary Quercetin on Growth Performance, Blood Biochemical Parameter, Immunoglobulin and Blood Antioxidant Activity in Broiler Chicks

Cited by 13 publications

References 31 publications

Comparative Efficacy of Selected Phytobiotics with Halquinol and Tetracycline on Gut Morphology, Ileal Digestibility, Cecal Microbiota Composition and Growth Performance in Broiler Chickens

Comparative Efficacy of Selected Phytobiotics with Halquinol and Tetracycline on Gut Morphology, Ileal Digestibility, Cecal Microbiota Composition and Growth Performance in Broiler Chickens

Effects of Inclusion of Different Doses of Persicaria odorata Leaf Meal (POLM) in Broiler Chicken Feed on Biochemical and Haematological Blood Indicators and Liver Histomorphological Changes

Dietary quercetin improved the growth, antioxidation, and flesh quality of grass carp (Ctenopharyngodon idella)

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